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Protein

POU domain protein

Gene

Pou4f1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi357 – 416HomeoboxPROSITE-ProRule annotationAdd BLAST60

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation
Biological processTranscription, Transcription regulationPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
POU domain proteinUniRule annotation
Gene namesi
Name:Pou4f1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

PTM / Processingi

Proteomic databases

PaxDbiQ78NA5.

Structurei

3D structure databases

ProteinModelPortaliQ78NA5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini262 – 339POU-specificInterPro annotationAdd BLAST78
Domaini355 – 415HomeoboxInterPro annotationAdd BLAST61

Sequence similaritiesi

Belongs to the POU transcription factor family.UniRule annotationSAAS annotation

Keywords - Domaini

HomeoboxPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG1168. Eukaryota.
ENOG410XPNX. LUCA.
HOVERGENiHBG031829.
PhylomeDBiQ78NA5.

Family and domain databases

CDDicd00086. homeodomain. 1 hit.
InterProiView protein in InterPro
IPR009057. Homeobox-like.
IPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR010982. Lambda_DNA-bd_dom.
IPR013847. POU.
IPR015584. POU4-TF1.
IPR000327. POU_dom.
PANTHERiPTHR11636:SF90. PTHR11636:SF90. 1 hit.
PfamiView protein in Pfam
PF00046. Homeobox. 1 hit.
PF00157. Pou. 1 hit.
PRINTSiPR00028. POUDOMAIN.
SMARTiView protein in SMART
SM00389. HOX. 1 hit.
SM00352. POU. 1 hit.
SUPFAMiSSF46689. SSF46689. 1 hit.
SSF47413. SSF47413. 1 hit.
PROSITEiView protein in PROSITE
PS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
PS00035. POU_1. 1 hit.
PS00465. POU_2. 1 hit.
PS51179. POU_3. 1 hit.

Sequencei

Sequence statusi: Complete.

Q78NA5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMSMNSKQPH FAMHPTLPEH KYPSLHSSSE AIRRACLPTP PLQSNLFASL
60 70 80 90 100
DETLLARAEA LAAVDIAVSQ GKSHPFKPDA TYHTMNSVPC TSTSTVPLAH
110 120 130 140 150
HHHHHHHHQA LEPGDLLDHI SSPSLALMAG AGGAGAAGGG GGAHDGPGGG
160 170 180 190 200
GGPGGGGGPG GGGPGGGGGG GGPGGGGGAP GGGLLGGSAH PHPHMHGLGH
210 220 230 240 250
LSHPAAAAAM NMPSGLPHPG LVAAAAHHGA AAAAAAAAAG QVAAASAAAA
260 270 280 290 300
VVGAAGLASI CDSDTDPREL EAFAERFKQR RIKLGVTQAD VGSALANLKI
310 320 330 340 350
PGVGSLSQST ICRFESLTLS HNNMIALKPI LQAWLEEAEG AQREKMNKPE
360 370 380 390 400
LFNGGEKKRK RTSIAAPEKR SLEAYFAVQP RPSSEKIAAI AEKLDLKKNV
410 420
VRVWFCNQRQ KQKRMKFSAT Y
Length:421
Mass (Da):42,781
Last modified:May 10, 2005 - v1
Checksum:i34EC99D789EBE939
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY217089 Genomic DNA. Translation: AAO60105.1.
UniGeneiMm.246550.

Similar proteinsi

Entry informationi

Entry nameiQ78NA5_MOUSE
AccessioniPrimary (citable) accession number: Q78NA5
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: September 27, 2017
This is version 96 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)