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Protein

Ubiquitin domain-containing protein UBFD1

Gene

Ubfd1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Ubiquitin domain-containing protein UBFD1
Gene namesi
Name:Ubfd1
Synonyms:D7Wsu128e
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 7

Organism-specific databases

MGIiMGI:107301. Ubfd1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002830761 – 368Ubiquitin domain-containing protein UBFD1Add BLAST368

Proteomic databases

EPDiQ78JW9.
MaxQBiQ78JW9.
PaxDbiQ78JW9.
PeptideAtlasiQ78JW9.
PRIDEiQ78JW9.

PTM databases

iPTMnetiQ78JW9.
PhosphoSitePlusiQ78JW9.

Expressioni

Gene expression databases

BgeeiENSMUSG00000030870.
CleanExiMM_UBFD1.
ExpressionAtlasiQ78JW9. baseline and differential.
GenevisibleiQ78JW9. MM.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000033158.

Structurei

Secondary structure

1368
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi145 – 151Combined sources7
Beta strandi154 – 160Combined sources7
Helixi166 – 177Combined sources12
Beta strandi187 – 191Combined sources5
Beta strandi194 – 197Combined sources4
Helixi198 – 201Combined sources4
Beta strandi207 – 211Combined sources5

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1V86NMR-A135-216[»]
ProteinModelPortaliQ78JW9.
SMRiQ78JW9.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ78JW9.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini143 – 218Ubiquitin-likePROSITE-ProRule annotationAdd BLAST76

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi12 – 15Poly-Arg4

Sequence similaritiesi

Contains 1 ubiquitin-like domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG1872. Eukaryota.
ENOG410XP96. LUCA.
GeneTreeiENSGT00390000012857.
HOGENOMiHOG000247033.
HOVERGENiHBG052799.
InParanoidiQ78JW9.
OMAiPLRERWV.
OrthoDBiEOG091G0HGN.
PhylomeDBiQ78JW9.
TreeFamiTF333280.

Family and domain databases

InterProiIPR029071. Ubiquitin-rel_dom.
IPR019954. Ubiquitin_CS.
IPR000626. Ubiquitin_dom.
[Graphical view]
PfamiPF00240. ubiquitin. 1 hit.
[Graphical view]
SMARTiSM00213. UBQ. 1 hit.
[Graphical view]
SUPFAMiSSF54236. SSF54236. 1 hit.
PROSITEiPS00299. UBIQUITIN_1. 1 hit.
PS50053. UBIQUITIN_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q78JW9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLKRGRGRPG KRRRRVSIET STCFRPACVK LGAGAGANLR QLASSRRPLR
60 70 80 90 100
SWWVLYTIIM AAAGAPDGME EPGMDTEAEA VATEAPARPL NCVEAEAAVG
110 120 130 140 150
AAAEDSCDAR GNLQPAPAQP PGDPAAQASV SNGEDAGGGV GKELVDLKII
160 170 180 190 200
WNKTKHDVKV PLDSTGSELK QKIHSITGLP PAMQKVMYKG LVPEDKTLRE
210 220 230 240 250
IKVTSGAKIM VVGSTINDVL AVNTPKDAAQ QDAKAEENKK EPLCRQKQHR
260 270 280 290 300
KVLDKGKPED VMPSVKGAQE RLPTVPLSGM YNKSGGKVRL TFKLEQDQLW
310 320 330 340 350
IGTKERTEKL PMGSIKNVVS EPIEGHEDYH MMAFQLGPTE ASYYWVYWVP
360
TQYVDAIKDT VLGKWQYF
Length:368
Mass (Da):40,143
Last modified:September 19, 2006 - v2
Checksum:iE253230620385FD2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC011313 mRNA. Translation: AAH11313.2.
CCDSiCCDS21808.1.
RefSeqiNP_613055.2. NM_138589.2.
UniGeneiMm.282122.

Genome annotation databases

EnsembliENSMUST00000033158; ENSMUSP00000033158; ENSMUSG00000030870.
GeneIDi28018.
KEGGimmu:28018.
UCSCiuc009jof.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC011313 mRNA. Translation: AAH11313.2.
CCDSiCCDS21808.1.
RefSeqiNP_613055.2. NM_138589.2.
UniGeneiMm.282122.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1V86NMR-A135-216[»]
ProteinModelPortaliQ78JW9.
SMRiQ78JW9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000033158.

PTM databases

iPTMnetiQ78JW9.
PhosphoSitePlusiQ78JW9.

Proteomic databases

EPDiQ78JW9.
MaxQBiQ78JW9.
PaxDbiQ78JW9.
PeptideAtlasiQ78JW9.
PRIDEiQ78JW9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000033158; ENSMUSP00000033158; ENSMUSG00000030870.
GeneIDi28018.
KEGGimmu:28018.
UCSCiuc009jof.1. mouse.

Organism-specific databases

CTDi56061.
MGIiMGI:107301. Ubfd1.

Phylogenomic databases

eggNOGiKOG1872. Eukaryota.
ENOG410XP96. LUCA.
GeneTreeiENSGT00390000012857.
HOGENOMiHOG000247033.
HOVERGENiHBG052799.
InParanoidiQ78JW9.
OMAiPLRERWV.
OrthoDBiEOG091G0HGN.
PhylomeDBiQ78JW9.
TreeFamiTF333280.

Miscellaneous databases

ChiTaRSiUbfd1. mouse.
EvolutionaryTraceiQ78JW9.
PROiQ78JW9.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000030870.
CleanExiMM_UBFD1.
ExpressionAtlasiQ78JW9. baseline and differential.
GenevisibleiQ78JW9. MM.

Family and domain databases

InterProiIPR029071. Ubiquitin-rel_dom.
IPR019954. Ubiquitin_CS.
IPR000626. Ubiquitin_dom.
[Graphical view]
PfamiPF00240. ubiquitin. 1 hit.
[Graphical view]
SMARTiSM00213. UBQ. 1 hit.
[Graphical view]
SUPFAMiSSF54236. SSF54236. 1 hit.
PROSITEiPS00299. UBIQUITIN_1. 1 hit.
PS50053. UBIQUITIN_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiUBFD1_MOUSE
AccessioniPrimary (citable) accession number: Q78JW9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 3, 2007
Last sequence update: September 19, 2006
Last modified: November 30, 2016
This is version 92 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.