Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Glycophorin-C

Gene

Gypc

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Glycophorin-C
Alternative name(s):
CD_antigen: CD236
Gene namesi
Name:Gypc
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 18

Organism-specific databases

MGIiMGI:1098566. Gypc.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 25ExtracellularSequence analysisAdd BLAST25
Transmembranei26 – 46Helical; Signal-anchor for type III membrane proteinSequence analysisAdd BLAST21
Topological domaini47 – 95CytoplasmicSequence analysisAdd BLAST49

GO - Cellular componenti

  • cortical cytoskeleton Source: MGI
  • integral component of membrane Source: UniProtKB-KW
  • membrane Source: MGI
  • plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003784541 – 95Glycophorin-CAdd BLAST95

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei71PhosphoserineBy similarity1
Modified residuei78PhosphoserineCombined sources1
Modified residuei89PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

EPDiQ78HU7.
MaxQBiQ78HU7.
PaxDbiQ78HU7.
PRIDEiQ78HU7.

PTM databases

iPTMnetiQ78HU7.
PhosphoSitePlusiQ78HU7.

Expressioni

Gene expression databases

BgeeiENSMUSG00000090523.
ExpressionAtlasiQ78HU7. baseline and differential.
GenevisibleiQ78HU7. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000134317.

Structurei

3D structure databases

ProteinModelPortaliQ78HU7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycophorin-C family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410J2G2. Eukaryota.
ENOG410YT9G. LUCA.
GeneTreeiENSGT00510000049102.
InParanoidiQ78HU7.
KOiK06576.
OMAiHTNEDKG.
OrthoDBiEOG091G1481.
PhylomeDBiQ78HU7.
TreeFamiTF337016.

Family and domain databases

InterProiIPR003585. Neurexin-like.
[Graphical view]
SMARTiSM00294. 4.1m. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q78HU7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSPVSKPPP ELLEPNPGKS YGIMEIAIIA AVITAVALVL VCLLFLMLRY
60 70 80 90
LYRHKGTYHT NEAKGTEFAE SADAALQSDP ALQDAGDTSK KEYFI
Length:95
Mass (Da):10,329
Last modified:December 16, 2008 - v2
Checksum:iBF40FA45AFDF2B46
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY234183 mRNA. Translation: AAP70024.1.
BC027408 mRNA. Translation: AAH27408.2.
CCDSiCCDS57118.1.
RefSeqiNP_001041672.1. NM_001048207.1.
UniGeneiMm.292145.

Genome annotation databases

EnsembliENSMUST00000174459; ENSMUSP00000134317; ENSMUSG00000090523.
GeneIDi71683.
KEGGimmu:71683.
UCSCiuc008ejk.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY234183 mRNA. Translation: AAP70024.1.
BC027408 mRNA. Translation: AAH27408.2.
CCDSiCCDS57118.1.
RefSeqiNP_001041672.1. NM_001048207.1.
UniGeneiMm.292145.

3D structure databases

ProteinModelPortaliQ78HU7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000134317.

PTM databases

iPTMnetiQ78HU7.
PhosphoSitePlusiQ78HU7.

Proteomic databases

EPDiQ78HU7.
MaxQBiQ78HU7.
PaxDbiQ78HU7.
PRIDEiQ78HU7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000174459; ENSMUSP00000134317; ENSMUSG00000090523.
GeneIDi71683.
KEGGimmu:71683.
UCSCiuc008ejk.1. mouse.

Organism-specific databases

CTDi2995.
MGIiMGI:1098566. Gypc.

Phylogenomic databases

eggNOGiENOG410J2G2. Eukaryota.
ENOG410YT9G. LUCA.
GeneTreeiENSGT00510000049102.
InParanoidiQ78HU7.
KOiK06576.
OMAiHTNEDKG.
OrthoDBiEOG091G1481.
PhylomeDBiQ78HU7.
TreeFamiTF337016.

Miscellaneous databases

PROiQ78HU7.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000090523.
ExpressionAtlasiQ78HU7. baseline and differential.
GenevisibleiQ78HU7. MM.

Family and domain databases

InterProiIPR003585. Neurexin-like.
[Graphical view]
SMARTiSM00294. 4.1m. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiGLPC_MOUSE
AccessioniPrimary (citable) accession number: Q78HU7
Secondary accession number(s): Q6XFR5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 7, 2009
Last sequence update: December 16, 2008
Last modified: November 2, 2016
This is version 82 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.