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Protein

Mitogen-activated protein kinase

Gene

Mapk10

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.SAAS annotation

GO - Molecular functioni

Keywordsi

Molecular functionKinase, Serine/threonine-protein kinaseSAAS annotation, Transferase
LigandATP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Mitogen-activated protein kinaseSAAS annotation (EC:2.7.11.24SAAS annotation)
Gene namesi
Name:Mapk10Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1346863. Mapk10.

Subcellular locationi

PTM / Processingi

Proteomic databases

MaxQBiQ78GB8.
PRIDEiQ78GB8.

Structurei

3D structure databases

ProteinModelPortaliQ78GB8.
SMRiQ78GB8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiKOG0665. Eukaryota.
ENOG410XSHI. LUCA.
HOGENOMiHOG000233024.
HOVERGENiHBG014652.
KOiK04440.

Family and domain databases

InterProiView protein in InterPro
IPR011009. Kinase-like_dom.
IPR003527. MAP_kinase_CS.
IPR008351. MAPK_JNK.
IPR000719. Prot_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
PfamiView protein in Pfam
PF00069. Pkinase. 1 hit.
PRINTSiPR01772. JNKMAPKINASE.
SMARTiView protein in SMART
SM00220. S_TKc. 1 hit.
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiView protein in PROSITE
PS01351. MAPK. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.

Sequencei

Sequence statusi: Complete.

Q78GB8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSKSKVDNQF YSVEVGDSTF TVLKRYQNLK PIGSGAQGIV CAAYDAVLDR
60 70 80 90 100
NVAIKKLSRP FQNQTHAKRA YRELVLMKCV NHKNIISLLN VFTPQKTLEE
110 120 130 140 150
FQDVYLVMEL MDANLCQVIQ MELDHERMSY LLYQMLCGIK HLHSAGIIHR
160 170 180 190 200
DLKPSNIVVK SDCTLKILDF GLARTAGTSF MMTPYVVTRY YRAPEVILGM
210 220 230 240 250
GYKENVDIWS VGCIMGEMVR HKILFPGRDY IDQWNKVIEQ LGTPCPEFMK
260 270 280 290 300
KLQPTVRNYV ENRPKYAGLT FPKLFPDSLF PADSEHNKLK ASQARDLLSK
310 320 330 340 350
MLVIDPAKRI SVDDALQHPY INVWYDPAEV EAPPPQIYDK QLDEREHTIE
360 370 380 390 400
EWKELIYKEV MNSEEKTKNG VVKGQPSPSG AAVNSSESLP PSSSVNDISS
410 420
MSTDQTLASD TDSSLEASAG PLGCCR
Length:426
Mass (Da):48,128
Last modified:April 17, 2007 - v1
Checksum:i1022B6AC7774A666
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC046625 mRNA. Translation: AAH46625.2.
RefSeqiNP_001075036.1. NM_001081567.2.
NP_001297612.1. NM_001310683.1.
NP_001297615.1. NM_001310686.2.
NP_001305031.1. NM_001318102.1.
NP_001305060.1. NM_001318131.1.
XP_017176377.1. XM_017320888.1.
UniGeneiMm.39253.
Mm.472459.

Genome annotation databases

GeneIDi26414.
KEGGimmu:26414.
UCSCiuc008yjf.1. mouse.

Similar proteinsi

Entry informationi

Entry nameiQ78GB8_MOUSE
AccessioniPrimary (citable) accession number: Q78GB8
Entry historyiIntegrated into UniProtKB/TrEMBL: April 17, 2007
Last sequence update: April 17, 2007
Last modified: August 30, 2017
This is version 86 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)