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Protein

Virion infectivity factor

Gene

vif

Organism
Human immunodeficiency virus 1
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Biological processi

Keywordsi

Biological processHost-virus interactionSAAS annotation, Ubl conjugation pathwaySAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Virion infectivity factorUniRule annotation
Gene namesi
Name:vifImported
OrganismiHuman immunodeficiency virus 1Imported
Taxonomic identifieri11676 [NCBI]
Taxonomic lineageiVirusesRetro-transcribing virusesRetroviridaeOrthoretrovirinaeLentivirusPrimate lentivirus group
Virus hostiHomo sapiens (Human) [TaxID: 9606]
Proteomesi
  • UP000130908 Componenti: Genome
  • UP000171086 Componenti: Genome

Subcellular locationi

  • Host cell membrane SAAS annotation; Peripheral membrane protein SAAS annotation; Cytoplasmic side SAAS annotation
  • Host cytoplasm UniRule annotation
  • Host cell membrane UniRule annotation; Peripheral membrane protein UniRule annotation; Cytoplasmic side UniRule annotation
  • Virion UniRule annotation
  • Note: In the cytoplasm, seems to colocalize with intermediate filament vimentin. A fraction is associated with the cytoplasmic side of cellular membranes, presumably via the interaction with Pr55Gag precursor.UniRule annotation
  • Virion SAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

Host cell membraneSAAS annotation, Host cytoplasmSAAS annotation, Host membrane, Membrane, VirionSAAS annotation

Interactioni

Protein-protein interaction databases

DIPiDIP-46350N.

Family & Domainsi

Sequence similaritiesi

Belongs to the primate lentivirus group Vif protein family.UniRule annotationSAAS annotation

Family and domain databases

InterProiView protein in InterPro
IPR000475. Viral_infect.
PfamiView protein in Pfam
PF00559. Vif. 1 hit.
PRINTSiPR00349. VIRIONINFFCT.

Sequencei

Sequence statusi: Complete.

Q77YG0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MENRWQVMIV WQVDRMRIRT WKSLVKHHMY VSGKARGWFY RHHYESPHPR
60 70 80 90 100
ISSEVHIPLG DARLVITTYW GLHTGERDWH LGQGVSIEWR KKRYSTQVDP
110 120 130 140 150
ELADQLIHLY YFDCFSDSAI RKALLGHIVS PRCEYQAGHN KVGSLQYLAL
160 170 180 190
AALITPKKIK PPLPSVTKLT EDRWNKPQKT KGHRGSHTMN GH
Length:192
Mass (Da):22,513
Last modified:July 5, 2004 - v1
Checksum:iD22589F3955CBE40
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ167216 Genomic RNA. Translation: AAZ95229.1.
KJ925006 Genomic RNA. Translation: AIJ50270.1.
D86068 Genomic DNA. Translation: BAA12990.1.
Z30632 Genomic DNA. Translation: CAA83109.1.
RefSeqiNP_057851.1. NC_001802.1.

Genome annotation databases

GeneIDi155459.

Similar proteinsi

Entry informationi

Entry nameiQ77YG0_9HIV1
AccessioniPrimary (citable) accession number: Q77YG0
Secondary accession number(s): A0A076PX61
Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: November 22, 2017
This is version 94 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported