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Protein
Submitted name:

Vif

Gene

vif

Organism
Human immunodeficiency virus 1
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Biological processi

  1. viral life cycle Source: InterPro
Complete GO annotation...

Keywords - Biological processi

Host-virus interactionSAAS annotation, Ubl conjugation pathwaySAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
VifImported
Submitted name:
Vif (Viral infectivity factor)Imported
Submitted name:
Vif proteinImported
Gene namesi
Name:vifImported
OrganismiHuman immunodeficiency virus 1Imported
Taxonomic identifieri11676 [NCBI]
Taxonomic lineageiVirusesRetro-transcribing virusesRetroviridaeOrthoretrovirinaeLentivirusPrimate lentivirus group
Virus hostiHomo sapiens (Human) [TaxID: 9606]

Subcellular locationi

Host cytoplasm SAAS annotation. Host cell membrane SAAS annotation; Peripheral membrane protein SAAS annotation; Cytoplasmic side SAAS annotation. Virion SAAS annotation

GO - Cellular componenti

  1. host cell cytoplasm Source: UniProtKB-SubCell
  2. host cell plasma membrane Source: UniProtKB-SubCell
  3. membrane Source: UniProtKB-KW
  4. virion Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Host cell membraneSAAS annotation, Host cytoplasmSAAS annotation, Host membrane, Membrane, VirionSAAS annotation

Pathology & Biotechi

Keywords - Diseasei

AIDSUniRule annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 1818integraseImportedPRO_5000053727Add
BLAST

Keywords - PTMi

PhosphoproteinSAAS annotation

Interactioni

Protein-protein interaction databases

DIPiDIP-46350N.

Structurei

3D structure databases

ProteinModelPortaliQ77YG0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Family and domain databases

InterProiIPR000475. Viral_infect.
[Graphical view]
PfamiPF00559. Vif. 1 hit.
[Graphical view]
PRINTSiPR00349. VIRIONINFFCT.

Sequencei

Sequence statusi: Complete.

Q77YG0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MENRWQVMIV WQVDRMRIRT WKSLVKHHMY VSGKARGWFY RHHYESPHPR
60 70 80 90 100
ISSEVHIPLG DARLVITTYW GLHTGERDWH LGQGVSIEWR KKRYSTQVDP
110 120 130 140 150
ELADQLIHLY YFDCFSDSAI RKALLGHIVS PRCEYQAGHN KVGSLQYLAL
160 170 180 190
AALITPKKIK PPLPSVTKLT EDRWNKPQKT KGHRGSHTMN GH
Length:192
Mass (Da):22,513
Last modified:July 5, 2004 - v1
Checksum:iD22589F3955CBE40
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF033819 Genomic RNA. Translation: AAC82594.1.
DQ167216 Genomic RNA. Translation: AAZ95229.1.
KJ925006 Genomic RNA. Translation: AIJ50270.1.
D86068 Genomic DNA. Translation: BAA12990.1.
Z30632 Genomic DNA. Translation: CAA83109.1.
RefSeqiNP_057851.1. NC_001802.1.

Genome annotation databases

GeneIDi155459.
KEGGivg:155459.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF033819 Genomic RNA. Translation: AAC82594.1.
DQ167216 Genomic RNA. Translation: AAZ95229.1.
KJ925006 Genomic RNA. Translation: AIJ50270.1.
D86068 Genomic DNA. Translation: BAA12990.1.
Z30632 Genomic DNA. Translation: CAA83109.1.
RefSeqiNP_057851.1. NC_001802.1.

3D structure databases

ProteinModelPortaliQ77YG0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-46350N.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi155459.
KEGGivg:155459.

Family and domain databases

InterProiIPR000475. Viral_infect.
[Graphical view]
PfamiPF00559. Vif. 1 hit.
[Graphical view]
PRINTSiPR00349. VIRIONINFFCT.
ProtoNetiSearch...

Publicationsi

  1. "Spectrum of biological properties of human immunodeficiency virus (HIV-1) isolates."
    Cloyd M.W., Moore B.E.
    Virology 174:103-116(1989) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MCK1Imported.
  2. Cited for: NUCLEOTIDE SEQUENCE.
  3. Iwatani Y.
    Submitted (MAY-1996) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MCK1Imported.
  4. "Appendix 2: Retroviral taxonomy, protein structure, sequences, and genetic maps."
    Petropoulos C.J.
    (In) Coffin J.M. (eds.); RETROVIRUSES, pp.757-0, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York, NY, USA (1996)
    Cited for: NUCLEOTIDE SEQUENCE.
  5. Chappey C.
    Submitted (FEB-1999) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  6. "Predominance of a Rare Type of HIV-1 in Estonia."
    Adojaan M., Kivisild T., Mannik A., Krispin T., Ustina V., Zilmer K., Liebert E., Jaroslavtsev N., Priimagi L., Tefanova V., Schmidt J., Krohn K., Villems R., Salminen M., Ustav M.
    J. Acquir. Immune Defic. Syndr. 39:598-605(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: EST2002-394Imported.
  7. Partridge T.S.
    Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: IIIBImported.
  8. "The First Glance at the HLA Class I-Associated Immunopeptidome from HIV-1-Infected Cells."
    Ternette N., Yang H., Partridge T., Llano A., Cedeno S., Fischer R., Charles P., Dudek N., Purcell A., Borrow P., Mothe B., Crespo M., Dorrell L., Brander C., Kessler B., Hanke T.
    Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: IIIBImported.

Entry informationi

Entry nameiQ77YG0_9HIV1
AccessioniPrimary (citable) accession number: Q77YG0
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: April 1, 2015
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.