Q77Y31 (Q77Y31_9PLVG) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Vpx EMBL AAB99961.1

Submitted name:
Vpx protein EMBL AAC57422.1

Gene names

Name:

vpx EMBL AAB99961.1

Organism

Simian-Human immunodeficiency virus EMBL AAB99961.1

Taxonomic identifier

57667 [NCBI]

Taxonomic lineage

Viruses › Retro-transcribing viruses › Retroviridae › Orthoretrovirinae › Lentivirus › Primate lentivirus group › unclassified Primate lentivirus group

Protein attributes

Sequence length	112 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Disease	AIDS RuleBase RU003343
Gene Ontology (GO)
Biological process	viral infectious cycle Inferred from electronic annotation. Source: InterPro
Cellular component	host cell nucleus Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q77Y31 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: 7FD3BF982AFD7BEA	FASTA	112	12,873
	10 20 30 40 50 60 MSDPRERIPP GNSGEETIGE AFEWLNRTVE EINREAVNHL PRELIFQVWQ RSWEYWHDEQ 70 80 90 100 110 GMSPSYVKYR YLCLIQKALF MHCKKGCRCL GEGHGAGGWR PGPPPPPPPG LA

References

[1]	"Viral outcome of simian-human immunodeficiency virus SHIV-89.6P adapted to cynomolgus monkeys." Borsetti A., Baroncelli S., Maggiorella M.T., Bellino S., Moretti S., Sernicola L., Belli R., Ridolfi B., Farcomeni S., Negri D.R., Cafaro A., Ensoli B., Titti F. Arch. Virol. 153:463-472(2008) [PubMed: 18080858] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: SHIV-89.6Pcy243 EMBL ABS11164.1.
[2]	"Derivation and biological characterization of a molecular clone of SHIV(KU-2) that causes AIDS, neurological disease, and renal disease in rhesus macaques." Liu Z.Q., Muhkerjee S., Sahni M., McCormick-Davis C., Leung K., Li Z., Gattone V.H.II., Tian C., Doms R.W., Hoffman T.L., Raghavan R., Narayan O., Stephens E.B. Virology 260:295-307(1999) [PubMed: 10417264] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: SHIVku2 EMBL AAV28697.1.
[3]	"A noninfectious simian/human immunodeficiency virus DNA vaccine that protects macaques against AIDS." Singh D.K., Liu Z., Sheffer D., Mackay G.A., Smith M., Dhillon S., Hegde R., Jia F., Adany I., Narayan O. J. Virol. 79:3419-3428(2005) [PubMed: 15731236] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: SHIVku2 EMBL AAV28697.1.
[4]	"An env gene derived from a primary human immunodeficiency virus type 1 isolate confers high in vivo replicative capacity to a chimeric simian/human immunodeficiency virus in rhesus monkeys." Reimann K.A., Li J.T., Voss G., Lekutis C., Tenner-Racz K., Racz P., Lin W., Montefiori D.C., Lee-Parritz D.E., Lu Y., Collman R.G., Sodroski J., Letvin N.L. J. Virol. 70:3198-3206(1996) [PubMed: 8627800] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: SHIV-89.6 EMBL AAB99961.1.
[5]	"Infection of cynomolgus monkeys with a chimeric HIV-1/SIVmac virus that expresses the HIV-1 envelope glycoproteins." Li J., Lord C.I., Haseltine W., Letvin N.L., Sodroski J. J. Acquir. Immune Defic. Syndr. 5:639-646(1992) [PubMed: 1613662] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: SHIV-4 EMBL AAB99971.1.
[6]	"Characterization of molecularly cloned simian-human immunodeficiency viruses causing rapid CD4+ lymphocyte depletion in rhesus monkeys." Karlsson G.B., Halloran M., Li J., Park I.W., Gomila R., Reimann K.A., Axthelm M.K., Iliff S.A., Letvin N.L., Sodroski J. J. Virol. 71:4218-4225(1997) [PubMed: 9151808] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: SHIV-89.6P EMBL AAC57422.1.
[7]	"Changes in human immunodeficiency virus type 1 envelope glycoproteins responsible for the pathogenicity of a multiply passaged simian-human immunodeficiency virus (SHIV-HXBc2)." Cayabyab M., Karlsson G.B., Etemad-Moghadam B.A., Hofmann W., Steenbeke T., Halloran M., Fanton J.W., Axthelm M.K., Letvin N.L., Sodroski J.G. J. Virol. 73:976-984(1999) [PubMed: 9882298] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[8]	"Generation of the pathogenic R5-tropic simian/human immunodeficiency virus SHIVAD8 by serial passaging in rhesus macaques." Nishimura Y., Shingai M., Willey R., Sadjadpour R., Lee W.R., Brown C.R., Brenchley J.M., Buckler-White A., Petros R., Eckhaus M., Hoffman V., Igarashi T., Martin M.A. J. Virol. 84:4769-4781(2010) [PubMed: 20147396] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[9]	"Rapid dissemination of a pathogenic simian/human immunodeficiency virus to systemic organs and active replication in lymphoid tissues following intrarectal infection." Miyake A., Ibuki K., Enose Y., Suzuki H., Horiuchi R., Motohara M., Saito N., Nakasone T., Honda M., Watanabe T., Miura T., Hayami M. J. Gen. Virol. 87:1311-1320(2006) [PubMed: 16603534] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: SHIV-C2/1 EMBL AAL55641.1.
[10]	Nishimura Y., Shingai M., Willey R., Sadjadpour R., Lee W.R., Brown C.R., Brenchley J.M., Buckler-White A., Petros R., Eckhaus M., Hoffman V., Igarashi T., Martin M.A. Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[11]	"Comparative genetic analysis of simian/human immunodeficiency viruses (SHIVs) with pathogenic property." Sakai K., Shinohara K., Takahashi E., Ami Y., Sasaki Y., Suzaki Y., Nakasone T., Honda M. Submitted (DEC-1999) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: SHIV-C2/1 EMBL AAL55641.1.
[12]	Reimann K.A., Li J.T., Voss G., Lekutis C., Tenner-Racz K., Racz P., Lin W., Montefiori D.C., Lee-Parritz D.E., Lu Y., Collman R.G., Sodroski J., Letvin N.L. Submitted (DEC-1997) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: SHIV-4 EMBL AAB99971.1 and SHIV-89.6 EMBL AAB99961.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF038398 Other DNA. Translation: AAB99961.1. AF038399 Other DNA. Translation: AAB99971.1. U89134 Other DNA. Translation: AAC57422.1. AF041850 Other DNA. Translation: AAD12137.1. AF217181 Other RNA. Translation: AAL55641.1. AY751799 Other RNA. Translation: AAV28697.1. EF672090 Other RNA. Translation: ABS11164.1. JN560959 Other DNA. Translation: AEM54724.1. JN560960 Other DNA. Translation: AEM54734.1. JN560961 Other DNA. Translation: AEM54744.1.
RefSeq	NP_046125.1. NC_001870.1.
3D structure databases
ProteinModelPortal	Q77Y31.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1446395.
Family and domain databases
InterPro	IPR000012. RetroV_VpR/X. [Graphical view]
Pfam	PF00522. VPR. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q77Y31_9PLVG

Accession

Primary (citable) accession number: Q77Y31

Entry history

Integrated into UniProtKB/TrEMBL:	July 5, 2004
Last sequence update:	July 5, 2004
Last modified:	October 19, 2011
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)