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Protein

DNA-directed RNA polymerase subunit

Gene

CPXV107 CDS

Organism
Cowpox virus (CPV)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Part of the DNA-dependent RNA polymerase which catalyzes the transcription of viral DNA into RNA using the four ribonucleoside triphosphates as substrates. Responsible for the transcription of early, intermediate and late genes.UniRule annotation

Catalytic activityi

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionNucleotidyltransferaseUniRule annotation, Transferase
Biological processTranscription

Names & Taxonomyi

Protein namesi
Recommended name:
DNA-directed RNA polymerase subunitUniRule annotation (EC:2.7.7.6UniRule annotation)
Gene namesi
Name:CPXV107 CDSImported
Synonyms:CPXV107Imported, O2RImported
ORF Names:CPXV_AUS1999_867_101Imported, CPXV_FIN2000_MAN_101Imported, CPXV_GER1980_EP4_101Imported, CPXV_GER2002_MKY_101Imported, CPXV_UK2000_K2984_101Imported
OrganismiCowpox virus (CPV)Imported
Taxonomic identifieri10243 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stagePoxviridaeChordopoxvirinaeOrthopoxvirus
Virus hostiApodemus sylvaticus (European woodmouse) [TaxID: 10129]
Bos taurus (Bovine) [TaxID: 9913]
Felis catus (Cat) (Felis silvestris catus) [TaxID: 9685]
Homo sapiens (Human) [TaxID: 9606]
Loxodonta africana (African elephant) [TaxID: 9785]
Microtus agrestis (Short-tailed field vole) [TaxID: 29092]
Mus musculus (Mouse) [TaxID: 10090]
Myodes glareolus (Bank vole) (Clethrionomys glareolus) [TaxID: 447135]
Proteomesi
  • UP000152733 Componenti: Genome
  • UP000098423 Componenti: Genome
  • UP000107082 Componenti: Genome
  • UP000099759 Componenti: Genome
  • UP000173670 Componenti: Genome
  • UP000154367 Componenti: Genome
  • UP000151407 Componenti: Genome
  • UP000137723 Componenti: Genome
  • UP000149052 Componenti: Genome
  • UP000159199 Componenti: Genome
  • UP000126894 Componenti: Genome
  • UP000115255 Componenti: Genome
  • UP000174976 Componenti: Genome
  • UP000113999 Componenti: Genome
  • UP000148121 Componenti: Genome
  • UP000163863 Componenti: Genome
  • UP000097445 Componenti: Genome
  • UP000123982 Componenti: Genome
  • UP000172256 Componenti: Genome
  • UP000168833 Componenti: Genome
  • UP000131496 Componenti: Genome

Subcellular locationi

GO - Cellular componenti

  • virion Source: UniProtKB-UniRule

Keywords - Cellular componenti

DNA-directed RNA polymeraseUniRule annotation, VirionUniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the poxviridae DNA-directed RNA polymerase 22 kDa subunit family.UniRule annotation

Family and domain databases

InterProiView protein in InterPro
IPR007937. RNA_Pol_22kDa_poxvir.
PfamiView protein in Pfam
PF05273. Pox_RNA_Pol_22. 1 hit.
PIRSFiPIRSF000744. RPO22. 1 hit.
ProDomiView protein in ProDom or Entries sharing at least one domain
PD011187. RNA_Pol_22kDa_poxvir. 1 hit.

Sequencei

Sequence statusi: Complete.

Q77DT3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNQYNVKYLA KILCLKTEIA RDPYAVINRN VLLRYTTDIE YNDLVTLITV
60 70 80 90 100
RHKIDSMKTV FQVFNESSIN YTPVDDDYGE PIIITSYLQK GHNKFPVNFL
110 120 130 140 150
YIDVVISDLF PSFVRLDTTE TNIVNSVLQT GDGKKTLRLP KMLETEIVVK
160 170 180
ILYRPNIPLK IVRFFRNNMV TGVEIADRSV ISVAD
Length:185
Mass (Da):21,342
Last modified:July 5, 2004 - v1
Checksum:iE4A289D674B3B9E0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF482758 Genomic DNA. Translation: AAM13550.1.
HQ407377 Genomic DNA. Translation: ADZ24105.1.
HQ420893 Genomic DNA. Translation: ADZ29218.1.
HQ420895 Genomic DNA. Translation: ADZ29646.1.
HQ420898 Genomic DNA. Translation: ADZ30289.1.
HQ420900 Genomic DNA. Translation: ADZ30712.1.
KC813491 Genomic DNA. Translation: AGY97155.1.
KC813492 Genomic DNA. Translation: AGY97368.1.
KC813493 Genomic DNA. Translation: AGY97584.1.
KC813494 Genomic DNA. Translation: AGY97803.1.
KC813496 Genomic DNA. Translation: AGY98229.1.
KC813497 Genomic DNA. Translation: AGY98443.1.
KC813498 Genomic DNA. Translation: AGY98659.1.
KC813499 Genomic DNA. Translation: AGY98880.1.
KC813500 Genomic DNA. Translation: AGY99092.1.
KC813502 Genomic DNA. Translation: AGY99506.1.
KC813504 Genomic DNA. Translation: AGY99933.1.
KC813507 Genomic DNA. Translation: AGZ00574.1.
KC813509 Genomic DNA. Translation: AGZ00992.1.
KC813511 Genomic DNA. Translation: AGZ01417.1.
KY369926 Genomic DNA. Translation: AQQ12964.1.
KY463519 Genomic DNA. Translation: ARB50330.1.
LN864566 Genomic DNA. Translation: CRL86867.1.
RefSeqiNP_619892.1. NC_003663.2.

Genome annotation databases

GeneIDi1485984.
KEGGivg:1485984.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiQ77DT3_COWPX
AccessioniPrimary (citable) accession number: Q77DT3
Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: June 7, 2017
This is version 40 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported