Q778I0 (Q778I0_HPV16) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Protein E7 PIRNR PIRNR003407

Gene names

Name:

E7 EMBL CAB45111.1

Organism

Human papillomavirus type 16 EMBL CAB45111.1

Taxonomic identifier

333760 [NCBI]

Taxonomic lineage

Viruses › dsDNA viruses, no RNA stage › Papillomaviridae › Alphapapillomavirus › Alphapapillomavirus 9

Virus host

Homo sapiens (Human) [TaxID: 9606]

Protein attributes

Sequence length	98 AA.
Sequence status	Fragment.
Protein existence	Inferred from homology

General annotation (Comments)

Function	E7 protein has both transforming and trans-activating activities By similarity. PIRNR PIRNR003407
Sequence similarities	Belongs to the papillomaviridae E7 protein family. PIRNR PIRNR003407

Ontologies

Keywords
Biological process	Host-virus interaction SAAS SAAS000148 Transcription Transcription regulation PIRNR PIRNR003407 SAAS SAAS000148
Developmental stage	Early protein PIRNR PIRNR003407
Domain	Zinc-finger SAAS SAAS000148
Ligand	DNA-binding PIRNR PIRNR003407 SAAS SAAS000148 Metal-binding Zinc
Molecular function	Activator PIRNR PIRNR003407 SAAS SAAS000148
Gene Ontology (GO)
Biological_process	transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW virus-host interaction Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	intracellular Inferred from electronic annotation. Source: InterPro
Molecular_function	DNA binding Inferred from electronic annotation. Source: UniProtKB-KW metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW sequence-specific DNA binding transcription factor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	98	1	EMBL CAB45111.1

Sequences

	Sequence		Length	Mass (Da)
	Q778I0 [UniParc]. Last modified May 10, 2005. Version 1. Checksum: 9BD612534CD2C9EB	FASTA	98	11,022
	10 20 30 40 50 60 MHGDTPTLHE YMLDLQPETT DLYCYEQLND SSEEEDEIDG PAGQAEPDRA HYNIVTFCCK 70 80 90 CDSTLRLCVQ STHVDIRTLE DLLMGTLGIV CPICSQKP

References

[1]

"Analysis of human papillomavirus type 16 E6 variants in relation to p53 codon 72 polymorphism genotypes in cervical carcinogenesis." van Duin M., Snijders P.J., Vossen M.T., Klaassen E., Voorhorst F., Verheijen R.H., Helmerhorst T.J., Meijer C.J., Walboomers J.M. J. Gen. Virol. 81:317-325(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: EA246T.2 EMBL CAB45111.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AJ388059 Genomic DNA. Translation: CAB45111.1.
RefSeq	NP_041326.1. NC_001526.2.
3D structure databases
ProteinModelPortal	Q778I0.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1489079.
Family and domain databases
InterPro	IPR000148. Papilloma_E7. [Graphical view]
Pfam	PF00527. E7. 1 hit. [Graphical view]
PIRSF	PIRSF003407. Papvi_E7. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q778I0_HPV16

Accession

Primary (citable) accession number: Q778I0

Entry history

Integrated into UniProtKB/TrEMBL:	May 10, 2005
Last sequence update:	May 10, 2005
Last modified:	April 3, 2013
This is version 39 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)