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Protein

Gag polyprotein

Gene
N/A
Organism
Human immunodeficiency virus 1
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRNA-bindingUniRule annotationSAAS annotation, Viral nucleoproteinUniRule annotation
Biological processHost-virus interactionUniRule annotationSAAS annotation, Viral release from host cellSAAS annotation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Gag polyproteinUniRule annotation
OrganismiHuman immunodeficiency virus 1Imported
Taxonomic identifieri11676 [NCBI]
Taxonomic lineageiVirusesRetro-transcribing virusesRetroviridaeOrthoretrovirinaeLentivirusPrimate lentivirus group
Virus hostiHomo sapiens (Human) [TaxID: 9606]

Subcellular locationi

  • Virion UniRule annotation
  • Host nucleus UniRule annotation
  • Host cytoplasm UniRule annotation
  • Host cytoplasm UniRule annotationSAAS annotation
  • Host nucleus UniRule annotationSAAS annotation
  • Virion UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Capsid proteinUniRule annotationSAAS annotation, Host cytoplasmUniRule annotationSAAS annotation, Host nucleusUniRule annotationSAAS annotation, Virion

PTM / Processingi

Post-translational modificationi

Gag-Pol polyprotein: Specific enzymatic cleavages by the viral protease yield mature proteins.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliQ77804
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini386 – 401CCHC-typeInterPro annotationAdd BLAST16
Domaini408 – 423CCHC-typeInterPro annotationAdd BLAST16

Keywords - Domaini

RepeatSAAS annotation, Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Family and domain databases

Gene3Di1.10.1200.30, 1 hit
1.10.150.90, 1 hit
1.10.375.10, 1 hit
InterProiView protein in InterPro
IPR000721 Gag_p24
IPR014817 Gag_p6
IPR000071 Lentvrl_matrix_N
IPR012344 Matrix_HIV/RSV_N
IPR008916 Retrov_capsid_C
IPR008919 Retrov_capsid_N
IPR010999 Retrovr_matrix
IPR001878 Znf_CCHC
IPR036875 Znf_CCHC_sf
PfamiView protein in Pfam
PF00540 Gag_p17, 1 hit
PF00607 Gag_p24, 1 hit
PF08705 Gag_p6, 1 hit
PF00098 zf-CCHC, 2 hits
PRINTSiPR00234 HIV1MATRIX
SMARTiView protein in SMART
SM00343 ZnF_C2HC, 2 hits
SUPFAMiSSF47836 SSF47836, 1 hit
SSF47943 SSF47943, 1 hit
SSF57756 SSF57756, 1 hit
PROSITEiView protein in PROSITE
PS50158 ZF_CCHC, 2 hits

Sequencei

Sequence statusi: Fragment.

Q77804-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGARASVLSG GKLDSWEKIR LRPGGKKKYR LKHLVWASRE LERFALNPGL
60 70 80 90 100
LETAEGCQQL MEQLQSALGT ESKELKSLYN TIAVLWCVHQ RIDIKDTKEA
110 120 130 140 150
LDKIEAVQNK SKQKTQQAAA ATGSSSQNYP IVQNAQGQMV HQPMSPRTLN
160 170 180 190 200
AWVKVIEEKA FSPEVIPMFT ALSEGATPQD LNMMLNIVGG HQAAMQMLKD
210 220 230 240 250
TINEEAAEWD RVHPVHAGPI PPGQMREPRG SDIAGTTSTL QEQIGWMTSN
260 270 280 290 300
PPIPVGDIYK RWIILGLNKI VRMYSPVSIL DIRQGPKEPF RDYVDRFFKT
310 320 330 340 350
LRAEQATQEV KNWMTETLLV QNANPDCKSI LRALGPGATL EEMMTSCQGV
360 370 380 390 400
GGPGHKARVL AEAMSQVQQS NIMMQRGDFR GQRTIKCFNC GKEGHLARNC
410 420 430 440 450
KAPRKKGCWK CGKEGHQMKD CTERQANFLG KIWPSTKGRP GNFPQSRPEP
460 470 480
TAPLAESFGM GEEITSPPKQ EPREQGLYPP LTSLKS
Length:486
Mass (Da):54,094
Last modified:November 1, 1996 - v1
Checksum:i74DE60C3E2D08277
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L11763 Genomic DNA Translation: AAA44317.1
PIRiS49086

Keywords - Coding sequence diversityi

Ribosomal frameshiftingSAAS annotation

Similar proteinsi

Entry informationi

Entry nameiQ77804_9HIV1
AccessioniPrimary (citable) accession number: Q77804
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: March 28, 2018
This is version 112 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health