Q76ZX2 (VK07_VACCA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Protein K7

Gene names

Ordered Locus Names:

MVA028R, ACAM3000_MVA_028

Organism

Vaccinia virus (strain Ankara) (VACV)

Taxonomic identifier

126794 [NCBI]

Taxonomic lineage

Viruses › dsDNA viruses, no RNA stage › Poxviridae › Chordopoxvirinae › Orthopoxvirus › Vaccinia virus

Virus host

Homo sapiens (Human) [TaxID: 9606]

Protein attributes

Sequence length	149 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the poxviruses K7 family.

Ontologies

Keywords
Biological process	Host-virus interaction Inhibition of host IFN-mediated response initiation by virus Inhibition of host TBK1-IKBKE-DDX3 complex by virus Inhibition of host innate immune response by virus Viral immunoevasion
Gene Ontology (GO)
Biological process	evasion by virus of host immune response Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 149	149	Protein K7		PRO_0000099607

Sequences

	Sequence		Length	Mass (Da)
	Q76ZX2 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: B3E972A93DF97DC8	FASTA	149	17,468
	10 20 30 40 50 60 MATKLDYEDA VFYFVDDDKI CSRDSIIDLI DEYITWRNHV IVFNKDITSC GRLYKELMKF 70 80 90 100 110 120 DDVAIRYYGI DKINEIVEAM SEGDHYINFT KVHDQESLFA TIGICAKITE HWGYKKISES 130 140 RFQSLGNITD LMTDDNINIL ILFLEKKLN

References

[1]	"The complete genomic sequence of the modified vaccinia Ankara strain: comparison with other orthopoxviruses." Antoine G., Scheiflinger F., Dorner F., Falkner F.G. Virology 244:365-396(1998) [PubMed: 9601507] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	Esposito J.J., Frace M., Sammons S.A., Olsen-Rasmussen M.S., Osborne J., Khristova M., Wohlhueter R.M. Submitted (APR-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Isolate Acambis 3000.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U94848 Genomic DNA. Translation: AAB96484.1. AY603355 Genomic DNA. Translation: AAT10426.1.
RefSeq	YP_232921.1. NC_006998.1.
3D structure databases
ProteinModelPortal	Q76ZX2.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3707496.
Phylogenomic databases
ProtClustDB	PHA2933.
Family and domain databases
InterPro	IPR009174. Orthopox_K7. IPR022819. Poxvirus. [Graphical view]
Pfam	PF06227. Orthopox_N1. 1 hit. [Graphical view]
PIRSF	PIRSF003764. VAC_K7R. 1 hit.
ProtoNet	Search...

Entry information

Entry name

VK07_VACCA

Accession

Primary (citable) accession number: Q76ZX2

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 7, 2004
Last sequence update:	July 5, 2004
Last modified:	September 21, 2011
This is version 24 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Viral Protein Annotation Program