Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

DNA-directed RNA polymerase subunit

Gene

MVA088R

Organism
Vaccinia virus (strain Ankara) (VACV)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Part of the DNA-dependent RNA polymerase which catalyzes the transcription of viral DNA into RNA using the four ribonucleoside triphosphates as substrates. Responsible for the transcription of early, intermediate and late genes.UniRule annotation

Catalytic activityi

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionNucleotidyltransferaseUniRule annotation, Transferase
Biological processTranscription

Names & Taxonomyi

Protein namesi
Recommended name:
DNA-directed RNA polymerase subunitUniRule annotation (EC:2.7.7.6UniRule annotation)
Gene namesi
Name:MVA088RImported
ORF Names:ACAM3000_MVA_088Imported, CVA102Imported
OrganismiVaccinia virus (strain Ankara) (VACV)Imported
Taxonomic identifieri126794 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stagePoxviridaeChordopoxvirinaeOrthopoxvirusVaccinia virus
Virus hostiHomo sapiens (Human) [TaxID: 9606]
Proteomesi
  • UP000136916 Componenti: Genome
  • UP000172909 Componenti: Genome
  • UP000159908 Componenti: Genome

Subcellular locationi

GO - Cellular componenti

  • virion Source: UniProtKB-UniRule

Keywords - Cellular componenti

DNA-directed RNA polymeraseUniRule annotation, VirionUniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the poxviridae DNA-directed RNA polymerase 22 kDa subunit family.UniRule annotation

Family and domain databases

InterProiView protein in InterPro
IPR007937. RNA_Pol_22kDa_poxvir.
PfamiView protein in Pfam
PF05273. Pox_RNA_Pol_22. 1 hit.
PIRSFiPIRSF000744. RPO22. 1 hit.
ProDomiView protein in ProDom or Entries sharing at least one domain
PD011187. RNA_Pol_22kDa_poxvir. 1 hit.

Sequencei

Sequence statusi: Complete.

Q76RC8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNQYNVKYLA KILCLKTEIA RDPYAVINRN VLLRYTTDIE YNDLVTLITV
60 70 80 90 100
RHKIDSMKTV FQVFNESSIN YTPVDDDYGE PIIITSYLQK GHNKFPVNFL
110 120 130 140 150
YIDVVISDLF PSFVRLDTTE TNIVNSVLQT GDGKKTLRLP KMLETEIVVK
160 170 180
ILYRPNIPLK IVRFFRNNMV TGVEIADRSV ISVAD
Length:185
Mass (Da):21,342
Last modified:April 18, 2006 - v1
Checksum:iE4A289D674B3B9E0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U94848 Genomic DNA. Translation: AAB96505.1.
AY603355 Genomic DNA. Translation: AAT10486.1.
AM501482 Genomic DNA. Translation: CAM58266.1.
RefSeqiYP_232978.1. NC_006998.1.

Genome annotation databases

GeneIDi3707552.
KEGGivg:3707552.

Similar proteinsi

Entry informationi

Entry nameiQ76RC8_VACCA
AccessioniPrimary (citable) accession number: Q76RC8
Secondary accession number(s): A9J1R2
Entry historyiIntegrated into UniProtKB/TrEMBL: April 18, 2006
Last sequence update: April 18, 2006
Last modified: July 5, 2017
This is version 45 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported