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Q76NI1

- VKIND_HUMAN

UniProt

Q76NI1 - VKIND_HUMAN

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Protein

Protein very KIND

Gene

KNDC1

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at transcript leveli

Functioni

Probable guanine nucleotide exchange factor (GEF).

GO - Molecular functioni

  1. protein serine/threonine kinase activity Source: Ensembl
  2. Ras guanyl-nucleotide exchange factor activity Source: Ensembl

GO - Biological processi

  1. cerebellar granule cell differentiation Source: Ensembl
  2. positive regulation of protein phosphorylation Source: Ensembl
  3. regulation of dendrite morphogenesis Source: Ensembl
  4. small GTPase mediated signal transduction Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Guanine-nucleotide releasing factor

Names & Taxonomyi

Protein namesi
Recommended name:
Protein very KIND
Alternative name(s):
Cerebral protein 9
KIND domain-containing protein 1
Kinase non-catalytic C-lobe domain-containing protein 1
Ras-GEF domain-containing family member 2
Gene namesi
Name:KNDC1
Synonyms:C10orf23, KIAA1768, RASGEF2, VKIND
ORF Names:hucep-9
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 10

Organism-specific databases

HGNCiHGNC:29374. KNDC1.

Subcellular locationi

GO - Cellular componenti

  1. dendrite Source: Ensembl
  2. guanyl-nucleotide exchange factor complex Source: Ensembl
  3. neuronal cell body Source: Ensembl
Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134983621.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 17491749Protein very KINDPRO_0000307141Add
BLAST

Proteomic databases

PaxDbiQ76NI1.
PRIDEiQ76NI1.

PTM databases

PhosphoSiteiQ76NI1.

Expressioni

Tissue specificityi

Expressed specifically in the cerebral cortex.1 Publication

Gene expression databases

BgeeiQ76NI1.
CleanExiHS_KNDC1.
ExpressionAtlasiQ76NI1. baseline.
GenevestigatoriQ76NI1.

Organism-specific databases

HPAiHPA039624.

Interactioni

Protein-protein interaction databases

BioGridi124529. 2 interactions.
IntActiQ76NI1. 2 interactions.
STRINGi9606.ENSP00000304437.

Structurei

3D structure databases

ProteinModelPortaliQ76NI1.
SMRiQ76NI1. Positions 1508-1703.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini37 – 217181KIND 1PROSITE-ProRule annotationAdd
BLAST
Domaini444 – 608165KIND 2PROSITE-ProRule annotationAdd
BLAST
Domaini1246 – 1371126N-terminal Ras-GEFPROSITE-ProRule annotationAdd
BLAST
Domaini1468 – 1719252Ras-GEFPROSITE-ProRule annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili1133 – 119058Sequence AnalysisAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi724 – 885162Pro-richAdd
BLAST

Sequence similaritiesi

Contains 2 KIND domains.PROSITE-ProRule annotation
Contains 1 N-terminal Ras-GEF domain.PROSITE-ProRule annotation
Contains 1 Ras-GEF domain.PROSITE-ProRule annotation

Keywords - Domaini

Coiled coil, Repeat

Phylogenomic databases

eggNOGiNOG81994.
GeneTreeiENSGT00390000011408.
HOVERGENiHBG108658.
InParanoidiQ76NI1.
OrthoDBiEOG7P5T00.
PhylomeDBiQ76NI1.
TreeFamiTF336009.

Family and domain databases

Gene3Di1.10.840.10. 1 hit.
InterProiIPR011009. Kinase-like_dom.
IPR011019. KIND.
IPR000651. Ras-like_Gua-exchang_fac_N.
IPR023578. Ras_GEF_dom.
IPR001895. RASGEF_cat_dom.
[Graphical view]
PfamiPF00617. RasGEF. 1 hit.
PF00618. RasGEF_N. 1 hit.
[Graphical view]
SMARTiSM00750. KIND. 2 hits.
SM00229. RasGEFN. 1 hit.
[Graphical view]
SUPFAMiSSF48366. SSF48366. 3 hits.
SSF56112. SSF56112. 1 hit.
PROSITEiPS51377. KIND. 2 hits.
PS50009. RASGEF_CAT. 1 hit.
PS50212. RASGEF_NTER. 1 hit.
[Graphical view]

Sequences (6)i

Sequence statusi: Complete.

This entry describes 6 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: Q76NI1-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MQAMDPAAAD LYEEDGKDLD FYDFEPLPTL PEDEENVSLA DILSLRDRGL
60 70 80 90 100
SEQEAWAVCL ECSLSMRSVA HAAIFQSLCI TPDTLAFNTS GNVCFMEQLS
110 120 130 140 150
DDPEGAFVPP EFDVTGNTFE AHIYSLGATL KAALEYVAEP TLEPRLSQDL
160 170 180 190 200
EALLSRMQAE DPGDRPDLES IIALCEEKLQ LTSSCRVCRS LSAVGRRVLS
210 220 230 240 250
IESFGALQDV SESSWRERPA PGNAGPRRPP GDPSTDPEVL PTPEGPESET
260 270 280 290 300
SRGPRASPTK ALLSTPVRNG ESHSREGLAG LVLDAERTLG ELDRDALRRS
310 320 330 340 350
RLRKVQTFPR LLSDSPEATL CLPLTRGKSQ LPISELFSPD PRKAFLDRKN
360 370 380 390 400
GLSSFQAQPK CRLWPEQEPE HQLGRVPCAG RSTDRGPGVP GSPGQPETSH
410 420 430 440 450
PSQGPAEAPA DPRDASGEAQ TPRDDERIPE GARQLESAAA EQWVSLQDLL
460 470 480 490 500
SQLGRPFREY ELWALCLACL RALQTRPEHP AYLCLDSVLV AEDGAVLFQP
510 520 530 540 550
PPANGSYDSF FLAPELAEER LVTEKASVYC VAAVLWTAAK FSVPRNHKLA
560 570 580 590 600
LPRRLKTLLL DMARRSAPER PSAAEAIKVC GSYLLQRGMD SRKILAHLRA
610 620 630 640 650
SICQVYQEEE TISLQNAFSV VELKPSVAPA PEPSPGFLPV NSDTGLVAVP
660 670 680 690 700
GPVPGQHPCG EEATQLPAAF TSEATHFKPI VLAQNASVAR DQPALAQEES
710 720 730 740 750
EERGGQREGE GEEKLSLEAH AGSPSLKTPD GPVPGPGPQG AAPEPLGASV
760 770 780 790 800
QRDSAQGRPC PPPQAPANQP EGASSAAPGS PVPAPPTKAS ALPVEQGPAE
810 820 830 840 850
PIPPGVASGG LRPDALGPTT AHHGPRHPPK PPRSKATERP GQEPEGPGAT
860 870 880 890 900
PAGERDDQSP DSVPERPRPA DRRLCLPCVD ASPLPGRTAC PSLQEATRLI
910 920 930 940 950
QEEFAFDGYL DNGLEALIMG EYIFALKDLT FATFCGAISE KFCDLYWDEK
960 970 980 990 1000
LLQNLFKVVN GQASPSPSTA EEAGSQLEGS QSPRSPSSKR PSLHRLGKEK
1010 1020 1030 1040 1050
PAMARTSSRA PCSPTSVSDV DSDALSRGNF EVGFRPQRSV KAERAQQPEA
1060 1070 1080 1090 1100
GEDRRPAGGA SDVEAVTRLA RSKGVGPALS PGPAGFQSCS PGWCSAFYEA
1110 1120 1130 1140 1150
DCFGADVHNY VKDLGRQQAD GALPDAQSPE LEQQLMMEKR NYRKTLKFYQ
1160 1170 1180 1190 1200
KLLQKEKRNK GSDVKTMLSK LKGQLEEMKS RVQFLSLVKK YLQVMYAERW
1210 1220 1230 1240 1250
GLEPCTLPVI VNIAAAPCDT LDFSPLDESS SLIFYNVNKH PGGRQKARIL
1260 1270 1280 1290 1300
QAGTPLGLMA YLYSSDAFLE GYVQQFLYTF RYFCTPHDFL HFLLDRINST
1310 1320 1330 1340 1350
LTRAHQDPTS TFTKIYRRSL CVLQAWVEDC YAVDFPRNSG LLGKLEDFIS
1360 1370 1380 1390 1400
SKILPLDGSA KHLLGLLEVG MDRRAEGNPR GTDLENPREA EEDARPFNAL
1410 1420 1430 1440 1450
CKRLSEDGIS RKSFPWRLPR GNGLVLPPHK ERPYTIAAAL PKPCFLEDFY
1460 1470 1480 1490 1500
GPCAKTSEKG PYFLTEYSTH QLFSQLTLLQ QELFQKCHPV HFLNSRALGV
1510 1520 1530 1540 1550
MDKSTAIPKA SSSESLSAKT CSLFLPNYVQ DKYLLQLLRN ADDVSTWVAA
1560 1570 1580 1590 1600
EIVTSHTSKL QVNLLSKFLL IAKSCYEQRN FATAMQILSG LEHLAVRQSP
1610 1620 1630 1640 1650
AWRILPAKIA EVMEELKAVE VFLKSDSLCL MEGRRFRAQP TLPSAHLLAM
1660 1670 1680 1690 1700
HIQQLETGGF TMTNGAHRWS KLRNIAKVVS QVHAFQENPY TFSPDPKLQS
1710 1720 1730 1740
YLKQRIARFS GADISTLAAD SRANFHQVSS EKHSRKIQDK LRRMKATFQ
Length:1,749
Mass (Da):191,397
Last modified:October 23, 2007 - v2
Checksum:iFB5F6C6692BBCB06
GO
Isoform 2 (identifier: Q76NI1-2) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-65: Missing.
     1194-1206: VMYAERWGLEPCT → ASGLRAPLCPVRQ
     1207-1749: Missing.

Show »
Length:1,141
Mass (Da):122,639
Checksum:i631124F7586C846F
GO
Isoform 3 (identifier: Q76NI1-3) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-65: Missing.

Show »
Length:1,684
Mass (Da):184,133
Checksum:i2FE7062F7447A263
GO
Isoform 4 (identifier: Q76NI1-4) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1130-1396: ELEQQLMMEK...PREAEEDARP → VSPRPWHCRV...LSCRLLACTL
     1397-1749: Missing.

Show »
Length:1,397
Mass (Da):148,552
Checksum:i898CFE93F843B2E5
GO
Isoform 5 (identifier: Q76NI1-5) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-1258: Missing.

Show »
Length:491
Mass (Da):55,823
Checksum:iA8F9C33FB112DCA3
GO
Isoform 6 (identifier: Q76NI1-6) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-1584: Missing.

Show »
Length:165
Mass (Da):18,783
Checksum:iEC85325473AD06D2
GO

Sequence cautioni

The sequence BAB21859.1 differs from that shown. Reason: Erroneous initiation. Curated
The sequence CAI17339.1 differs from that shown. Reason: Erroneous gene model prediction. Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti346 – 3461L → P in BAD12625. 1 PublicationCurated
Sequence conflicti806 – 8061V → D in BAD12625. 1 PublicationCurated
Sequence conflicti925 – 9251A → G in BAD12625. 1 PublicationCurated
Sequence conflicti971 – 9711E → G in BAD12625. 1 PublicationCurated
Sequence conflicti1072 – 10721S → P in BAD12625. 1 PublicationCurated
Sequence conflicti1084 – 10841A → V in BAD12625. 1 PublicationCurated
Sequence conflicti1260 – 12601A → T in BAD12625. 1 PublicationCurated
Sequence conflicti1315 – 13151I → T in BAD12625. 1 PublicationCurated
Sequence conflicti1468 – 14681S → G in BAD12625. 1 PublicationCurated
Sequence conflicti1624 – 16241K → R in BAD12625. 1 PublicationCurated

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti436 – 4361E → G.1 Publication
Corresponds to variant rs3810964 [ dbSNP | Ensembl ].
VAR_035358
Natural varianti581 – 5811G → S.
Corresponds to variant rs35152544 [ dbSNP | Ensembl ].
VAR_035359
Natural varianti717 – 7171L → P.1 Publication
Corresponds to variant rs2998139 [ dbSNP | Ensembl ].
VAR_035360
Natural varianti1038 – 10381R → W.
Corresponds to variant rs35604376 [ dbSNP | Ensembl ].
VAR_061786
Natural varianti1332 – 13321A → T.
Corresponds to variant rs11101642 [ dbSNP | Ensembl ].
VAR_051902

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1 – 15841584Missing in isoform 6. 1 PublicationVSP_028592Add
BLAST
Alternative sequencei1 – 12581258Missing in isoform 5. 1 PublicationVSP_028593Add
BLAST
Alternative sequencei1 – 6565Missing in isoform 2 and isoform 3. 2 PublicationsVSP_028594Add
BLAST
Alternative sequencei1130 – 1396267ELEQQ…EDARP → VSPRPWHCRVGQGVSFQQSF LVTAGDRWHRVPRAPNRVTL VLVPPPRGCQDGQGPLPGLS STSRDRLVCTGAPGGSTSED REGLFSHGRPGDGFTGGPSM LVTRLRSVVFSVGQAQPPGP WAASLCSERKHQKRLPSKSR LGLVAAAWSGLSGQQCHPGS GAAATPPWPAGRGGLRPGSP GCRRGLQSSGRKVGPVTHSP DLGCILESPGTPGWMTGGAQ WPSAPGTSPTTVCLELSHRG KPPPASGHRSPSWGSSLLLS CRLLACTL in isoform 4. 1 PublicationVSP_028595Add
BLAST
Alternative sequencei1194 – 120613VMYAE…LEPCT → ASGLRAPLCPVRQ in isoform 2. 1 PublicationVSP_028596Add
BLAST
Alternative sequencei1207 – 1749543Missing in isoform 2. 1 PublicationVSP_028597Add
BLAST
Alternative sequencei1397 – 1749353Missing in isoform 4. 1 PublicationVSP_028598Add
BLAST

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB000781 mRNA. Translation: BAD12625.1.
AB051555 mRNA. Translation: BAB21859.1. Different initiation.
AK057756 mRNA. Translation: BAB71561.1.
AK131205 mRNA. Translation: BAD18397.1.
AL445199 Genomic DNA. Translation: CAM24665.1.
AL445199 Genomic DNA. Translation: CAI17339.1. Sequence problems.
AK074179 mRNA. Translation: BAB85005.1.
CCDSiCCDS7674.1. [Q76NI1-1]
RefSeqiNP_689856.6. NM_152643.6. [Q76NI1-1]
UniGeneiHs.530685.

Genome annotation databases

EnsembliENST00000304613; ENSP00000304437; ENSG00000171798. [Q76NI1-1]
ENST00000368571; ENSP00000357560; ENSG00000171798. [Q76NI1-2]
GeneIDi85442.
KEGGihsa:85442.
UCSCiuc001llz.1. human. [Q76NI1-1]
uc001lma.1. human. [Q76NI1-2]
uc001lmb.1. human. [Q76NI1-4]

Polymorphism databases

DMDMi160013711.

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB000781 mRNA. Translation: BAD12625.1 .
AB051555 mRNA. Translation: BAB21859.1 . Different initiation.
AK057756 mRNA. Translation: BAB71561.1 .
AK131205 mRNA. Translation: BAD18397.1 .
AL445199 Genomic DNA. Translation: CAM24665.1 .
AL445199 Genomic DNA. Translation: CAI17339.1 . Sequence problems.
AK074179 mRNA. Translation: BAB85005.1 .
CCDSi CCDS7674.1. [Q76NI1-1 ]
RefSeqi NP_689856.6. NM_152643.6. [Q76NI1-1 ]
UniGenei Hs.530685.

3D structure databases

ProteinModelPortali Q76NI1.
SMRi Q76NI1. Positions 1508-1703.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 124529. 2 interactions.
IntActi Q76NI1. 2 interactions.
STRINGi 9606.ENSP00000304437.

PTM databases

PhosphoSitei Q76NI1.

Polymorphism databases

DMDMi 160013711.

Proteomic databases

PaxDbi Q76NI1.
PRIDEi Q76NI1.

Protocols and materials databases

DNASUi 85442.
Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000304613 ; ENSP00000304437 ; ENSG00000171798 . [Q76NI1-1 ]
ENST00000368571 ; ENSP00000357560 ; ENSG00000171798 . [Q76NI1-2 ]
GeneIDi 85442.
KEGGi hsa:85442.
UCSCi uc001llz.1. human. [Q76NI1-1 ]
uc001lma.1. human. [Q76NI1-2 ]
uc001lmb.1. human. [Q76NI1-4 ]

Organism-specific databases

CTDi 85442.
GeneCardsi GC10P134974.
HGNCi HGNC:29374. KNDC1.
HPAi HPA039624.
neXtProti NX_Q76NI1.
PharmGKBi PA134983621.
HUGEi Search...
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG81994.
GeneTreei ENSGT00390000011408.
HOVERGENi HBG108658.
InParanoidi Q76NI1.
OrthoDBi EOG7P5T00.
PhylomeDBi Q76NI1.
TreeFami TF336009.

Miscellaneous databases

ChiTaRSi KNDC1. human.
GenomeRNAii 85442.
NextBioi 76025.
PROi Q76NI1.

Gene expression databases

Bgeei Q76NI1.
CleanExi HS_KNDC1.
ExpressionAtlasi Q76NI1. baseline.
Genevestigatori Q76NI1.

Family and domain databases

Gene3Di 1.10.840.10. 1 hit.
InterProi IPR011009. Kinase-like_dom.
IPR011019. KIND.
IPR000651. Ras-like_Gua-exchang_fac_N.
IPR023578. Ras_GEF_dom.
IPR001895. RASGEF_cat_dom.
[Graphical view ]
Pfami PF00617. RasGEF. 1 hit.
PF00618. RasGEF_N. 1 hit.
[Graphical view ]
SMARTi SM00750. KIND. 2 hits.
SM00229. RasGEFN. 1 hit.
[Graphical view ]
SUPFAMi SSF48366. SSF48366. 3 hits.
SSF56112. SSF56112. 1 hit.
PROSITEi PS51377. KIND. 2 hits.
PS50009. RASGEF_CAT. 1 hit.
PS50212. RASGEF_NTER. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Molecular cloning of a novel gene which is specifically expressed in human cerebral cortex."
    Yoshimoto M., Yazaki M., Matsumoto K., Takayama K.
    Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3), TISSUE SPECIFICITY, VARIANTS GLY-436 AND PRO-717.
    Tissue: Brain cortex.
  2. "Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."
    Nagase T., Kikuno R., Hattori A., Kondo Y., Okumura K., Ohara O.
    DNA Res. 7:347-355(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
    Tissue: Brain.
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 5 AND 6).
    Tissue: Brain and Cerebellum.
  4. "The DNA sequence and comparative analysis of human chromosome 10."
    Deloukas P., Earthrowl M.E., Grafham D.V., Rubenfield M., French L., Steward C.A., Sims S.K., Jones M.C., Searle S., Scott C., Howe K., Hunt S.E., Andrews T.D., Gilbert J.G.R., Swarbreck D., Ashurst J.L., Taylor A., Battles J.
    , Bird C.P., Ainscough R., Almeida J.P., Ashwell R.I.S., Ambrose K.D., Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Bates K., Beasley H., Bray-Allen S., Brown A.J., Brown J.Y., Burford D.C., Burrill W., Burton J., Cahill P., Camire D., Carter N.P., Chapman J.C., Clark S.Y., Clarke G., Clee C.M., Clegg S., Corby N., Coulson A., Dhami P., Dutta I., Dunn M., Faulkner L., Frankish A., Frankland J.A., Garner P., Garnett J., Gribble S., Griffiths C., Grocock R., Gustafson E., Hammond S., Harley J.L., Hart E., Heath P.D., Ho T.P., Hopkins B., Horne J., Howden P.J., Huckle E., Hynds C., Johnson C., Johnson D., Kana A., Kay M., Kimberley A.M., Kershaw J.K., Kokkinaki M., Laird G.K., Lawlor S., Lee H.M., Leongamornlert D.A., Laird G., Lloyd C., Lloyd D.M., Loveland J., Lovell J., McLaren S., McLay K.E., McMurray A., Mashreghi-Mohammadi M., Matthews L., Milne S., Nickerson T., Nguyen M., Overton-Larty E., Palmer S.A., Pearce A.V., Peck A.I., Pelan S., Phillimore B., Porter K., Rice C.M., Rogosin A., Ross M.T., Sarafidou T., Sehra H.K., Shownkeen R., Skuce C.D., Smith M., Standring L., Sycamore N., Tester J., Thorpe A., Torcasso W., Tracey A., Tromans A., Tsolas J., Wall M., Walsh J., Wang H., Weinstock K., West A.P., Willey D.L., Whitehead S.L., Wilming L., Wray P.W., Young L., Chen Y., Lovering R.C., Moschonas N.K., Siebert R., Fechtel K., Bentley D., Durbin R.M., Hubbard T., Doucette-Stamm L., Beck S., Smith D.R., Rogers J.
    Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  5. "The nucleotide sequence of a long cDNA clone isolated from human spleen."
    Jikuya H., Takano J., Nomura N., Kikuno R., Nagase T., Ohara O.
    Submitted (JAN-2002) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 579-1749 (ISOFORM 4).
    Tissue: Spleen.

Entry informationi

Entry nameiVKIND_HUMAN
AccessioniPrimary (citable) accession number: Q76NI1
Secondary accession number(s): B0QZC5
, Q5T233, Q6ZNH8, Q8TEE5, Q96LV7, Q9C095
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 23, 2007
Last sequence update: October 23, 2007
Last modified: October 29, 2014
This is version 87 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 10
    Human chromosome 10: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3