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Protein

Glutathione peroxidase

Gene

Gpx4

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase, PeroxidaseUniRule annotationSAAS annotationImported
LigandSeleniumImported

Names & Taxonomyi

Protein namesi
Recommended name:
Glutathione peroxidaseUniRule annotation
Gene namesi
Name:Gpx4Imported
Synonyms:GPx4Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:104767. Gpx4.

PTM / Processingi

Proteomic databases

MaxQBiQ76LV0.
PRIDEiQ76LV0.

Expressioni

Gene expression databases

BgeeiENSMUSG00000075706.

Structurei

3D structure databases

ProteinModelPortaliQ76LV0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glutathione peroxidase family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG1651. Eukaryota.
COG0386. LUCA.
HOVERGENiHBG004333.
KOiK05361.
OrthoDBiEOG091G0OJG.
TreeFamiTF338735.

Family and domain databases

CDDicd00340. GSH_Peroxidase. 1 hit.
InterProiView protein in InterPro
IPR000889. Glutathione_peroxidase.
IPR029759. GPX_AS.
IPR029760. GPX_CS.
IPR012336. Thioredoxin-like_fold.
PANTHERiPTHR11592. PTHR11592. 1 hit.
PfamiView protein in Pfam
PF00255. GSHPx. 1 hit.
PRINTSiPR01011. GLUTPROXDASE.
SUPFAMiSSF52833. SSF52833. 1 hit.
PROSITEiView protein in PROSITE
PS00460. GLUTATHIONE_PEROXID_1. 1 hit.
PS00763. GLUTATHIONE_PEROXID_2. 1 hit.
PS51355. GLUTATHIONE_PEROXID_3. 1 hit.

Sequencei

Sequence statusi: Complete.

Q76LV0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGRAAARKRG RCRQRGGSPR GRRRRGPGRQ SPRKRPGPRR RKARARRRRR
60 70 80 90 100
ARPRRMEPIP EPFNPGPLLQ EPPQYCNSSE FLGLCASRDD WRCARSMHEF
110 120 130 140 150
SAKDIDGHMV CLDKYRGFVC IVTNVASQUG KTDVNYTQLV DLHARYAECG
160 170 180 190 200
LRILAFPCNQ FGRQEPGSNQ EIKEFAAGYN VKFDMYSKIC VNGDDAHPLW
210 220 230 240 250
KWMKVQPKGR GMLGNAIKWN FTKFLIDKNG CVVKRYGPME EPQVIEKDLP

CYL
Length:253
Mass (Da):29,194
Last modified:February 26, 2008 - v2
Checksum:iC55E2827533CDBF3
GO

Non-standard residue

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-standard residuei129SelenocysteineImported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB072797 mRNA. Translation: BAC87835.1.
RefSeqiNP_001032830.2. NM_001037741.3.
UniGeneiMm.332810.
Mm.359573.

Genome annotation databases

GeneIDi625249.
KEGGimmu:625249.
UCSCiuc007gbl.2. mouse.

Keywords - Coding sequence diversityi

SelenocysteineImported

Similar proteinsi

Entry informationi

Entry nameiQ76LV0_MOUSE
AccessioniPrimary (citable) accession number: Q76LV0
Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: February 26, 2008
Last modified: September 27, 2017
This is version 116 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)