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Protein
Submitted name:

Interleukin-1 receptor type 1

Gene

Il1r1

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. interleukin-1, Type I, activating receptor activity Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

ReceptorImported

Names & Taxonomyi

Protein namesi
Submitted name:
Interleukin-1 receptor type 1Imported
Gene namesi
Name:Il1r1Imported
Synonyms:il1r-1Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi2892. Il1r1.

Expressioni

Gene expression databases

GenevestigatoriQ76LI4.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000019673.

Structurei

3D structure databases

ProteinModelPortaliQ76LI4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOVERGENiHBG052103.

Family and domain databases

Gene3Di2.60.40.10. 2 hits.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003599. Ig_sub.
IPR015621. IL-1_rcpt_fam.
IPR004076. IL-1_rcpt_I-typ.
IPR004074. IL-1_rcpt_I/II-typ.
[Graphical view]
PANTHERiPTHR11890. PTHR11890. 1 hit.
PRINTSiPR01538. INTRLEUKN1R1.
PR01536. INTRLKN1R12F.
SMARTiSM00409. IG. 2 hits.
[Graphical view]
PROSITEiPS50835. IG_LIKE. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q76LI4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
AKMEDSGYYY CIMRNSTYCL KTKITMSVLE NDPGLCYNTQ ASFIQRLHVA
60 70 80 90 100
GDGSLVCPYL DFFKDENNEL PKVQWYKNCK PLPLDDGNFF GFKNKLMVMN
110 120 130 140 150
VAEEHRGNYT CRTSYTYQGK QYPVTRVITF ITIDDSKRDR PVIMSPRDET
160 170 180 190 200
MEADPGSTIQ LICNVTGQFT DLVYWKWNGS EIEWDDPILA EDYQFLEHPS
210 220 230 240
AKRKYTLITT LNVSEVKSQF YRYPFICFVK NTHILETAHV RLVYPVPDF
Length:249
Mass (Da):29,078
Last modified:July 5, 2004 - v1
Checksum:i5169FA0A1979249C
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei249 – 2491Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB079118 mRNA. Translation: BAD15353.1.
UniGeneiRn.9758.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB079118 mRNA. Translation: BAD15353.1.
UniGeneiRn.9758.

3D structure databases

ProteinModelPortaliQ76LI4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000019673.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

RGDi2892. Il1r1.

Phylogenomic databases

HOVERGENiHBG052103.

Gene expression databases

GenevestigatoriQ76LI4.

Family and domain databases

Gene3Di2.60.40.10. 2 hits.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003599. Ig_sub.
IPR015621. IL-1_rcpt_fam.
IPR004076. IL-1_rcpt_I-typ.
IPR004074. IL-1_rcpt_I/II-typ.
[Graphical view]
PANTHERiPTHR11890. PTHR11890. 1 hit.
PRINTSiPR01538. INTRLEUKN1R1.
PR01536. INTRLKN1R12F.
SMARTiSM00409. IG. 2 hits.
[Graphical view]
PROSITEiPS50835. IG_LIKE. 2 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Up-regulation of IL-1 receptor through PI3K/Akt is essential for the induction of iNOS gene expression in hepatocytes."
    Teshima S., Nakanishi H., Nishizawa M., Kitagawa K., Kaibori M., Yamada M., Habara K., Kwon A.H., Kamiyama Y., Ito S., Okumura T.
    J. Hepatol. 40:616-623(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ76LI4_RAT
AccessioniPrimary (citable) accession number: Q76LI4
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: October 29, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.