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Protein

Ankyrin repeat domain-containing protein 46

Gene

Ankrd46

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Ankyrin repeat domain-containing protein 46
Alternative name(s):
Ankyrin repeat small protein
Short name:
ANK-S
Gene namesi
Name:Ankrd46
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 7

Organism-specific databases

RGDi1309382. Ankrd46.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei195 – 21521HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 228228Ankyrin repeat domain-containing protein 46PRO_0000244580Add
BLAST

Proteomic databases

PaxDbiQ76K24.
PRIDEiQ76K24.

Expressioni

Gene expression databases

GenevisibleiQ76K24. RN.

Interactioni

Protein-protein interaction databases

BioGridi256400. 1 interaction.
STRINGi10116.ENSRNOP00000034048.

Structurei

3D structure databases

ProteinModelPortaliQ76K24.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati11 – 4030ANK 1Add
BLAST
Repeati44 – 7431ANK 2Add
BLAST
Repeati77 – 10327ANK 3Add
BLAST
Repeati107 – 13832ANK 4Add
BLAST

Sequence similaritiesi

Contains 4 ANK repeats.PROSITE-ProRule annotation

Keywords - Domaini

ANK repeat, Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0508. Eukaryota.
COG0666. LUCA.
GeneTreeiENSGT00790000123078.
HOGENOMiHOG000033966.
HOVERGENiHBG080854.
InParanoidiQ76K24.
OMAiATEYQGN.
OrthoDBiEOG7B5WWW.
PhylomeDBiQ76K24.
TreeFamiTF330790.

Family and domain databases

Gene3Di1.25.40.20. 1 hit.
InterProiIPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
[Graphical view]
PfamiPF12796. Ank_2. 1 hit.
[Graphical view]
SMARTiSM00248. ANK. 3 hits.
[Graphical view]
SUPFAMiSSF48403. SSF48403. 1 hit.
PROSITEiPS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q76K24-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSYVFVNDSS QTNVPLLQAC IDGDFTYSKR LLESGFDPNI RDSRGRTGLH
60 70 80 90 100
LAAARGNVDI CQLLHKFGAD PLATDYQGNT ALHLCGHVDT IQFLVSNGLK
110 120 130 140 150
IDICNHQGAT PLVLAKRRGV NKDVIRLLES LEEQEVKGFN RGTHSKLETM
160 170 180 190 200
QTAESESAME SHSLLNPNLQ QGEGVLSSFR TTWQEFVEDL GFWRVLLLIL
210 220
VIALLSLGIA YYVSGVLPFV DNQPGLVH
Length:228
Mass (Da):25,181
Last modified:July 5, 2004 - v1
Checksum:i18FED588F822528C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB095364 mRNA. Translation: BAD05179.1.
BC105616 mRNA. Translation: AAI05617.1.
RefSeqiNP_001013970.1. NM_001013948.1.
XP_006241592.1. XM_006241530.2.
XP_006241593.1. XM_006241531.2.
XP_006241594.1. XM_006241532.2.
XP_006241595.1. XM_006241533.2.
UniGeneiRn.11978.

Genome annotation databases

EnsembliENSRNOT00000036904; ENSRNOP00000034048; ENSRNOG00000025504.
GeneIDi299982.
KEGGirno:299982.
UCSCiRGD:1309382. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB095364 mRNA. Translation: BAD05179.1.
BC105616 mRNA. Translation: AAI05617.1.
RefSeqiNP_001013970.1. NM_001013948.1.
XP_006241592.1. XM_006241530.2.
XP_006241593.1. XM_006241531.2.
XP_006241594.1. XM_006241532.2.
XP_006241595.1. XM_006241533.2.
UniGeneiRn.11978.

3D structure databases

ProteinModelPortaliQ76K24.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi256400. 1 interaction.
STRINGi10116.ENSRNOP00000034048.

Proteomic databases

PaxDbiQ76K24.
PRIDEiQ76K24.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000036904; ENSRNOP00000034048; ENSRNOG00000025504.
GeneIDi299982.
KEGGirno:299982.
UCSCiRGD:1309382. rat.

Organism-specific databases

CTDi157567.
RGDi1309382. Ankrd46.

Phylogenomic databases

eggNOGiKOG0508. Eukaryota.
COG0666. LUCA.
GeneTreeiENSGT00790000123078.
HOGENOMiHOG000033966.
HOVERGENiHBG080854.
InParanoidiQ76K24.
OMAiATEYQGN.
OrthoDBiEOG7B5WWW.
PhylomeDBiQ76K24.
TreeFamiTF330790.

Miscellaneous databases

NextBioi646080.
PROiQ76K24.

Gene expression databases

GenevisibleiQ76K24. RN.

Family and domain databases

Gene3Di1.25.40.20. 1 hit.
InterProiIPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
[Graphical view]
PfamiPF12796. Ank_2. 1 hit.
[Graphical view]
SMARTiSM00248. ANK. 3 hits.
[Graphical view]
SUPFAMiSSF48403. SSF48403. 1 hit.
PROSITEiPS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 2 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Human and rat homologues of a novel gene ank-s expressed in the senescence accelerated mouse prone 8 (SAMP8)."
    Yamamura N., Koike N., Ohkuma Y., Uehara T., Nomura Y., Sakaki Y., Tashiro T., Furihata C.
    Submitted (NOV-2002) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Tissue: Brain.
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Testis.

Entry informationi

Entry nameiANR46_RAT
AccessioniPrimary (citable) accession number: Q76K24
Secondary accession number(s): Q0VGK7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: July 5, 2004
Last modified: November 11, 2015
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.