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Protein
Submitted name:

Embryonic transglutaminase

Gene

eTGase

Organism
Oryzias latipes (Medaka fish) (Japanese ricefish)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

Cofactori

Note: Binds 1 calcium ion per subunit.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei330 – 3301UniRule annotation
Active sitei389 – 3891UniRule annotation
Active sitei412 – 4121UniRule annotation
Metal bindingi452 – 4521CalciumUniRule annotation
Metal bindingi454 – 4541CalciumUniRule annotation
Metal bindingi501 – 5011CalciumUniRule annotation
Metal bindingi506 – 5061CalciumUniRule annotation

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. protein-glutamine gamma-glutamyltransferase activity Source: InterPro

GO - Biological processi

  1. peptide cross-linking Source: InterPro
Complete GO annotation...

Keywords - Ligandi

CalciumUniRule annotation, Metal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Embryonic transglutaminaseImported
Gene namesi
Name:eTGaseImported
OrganismiOryzias latipes (Medaka fish) (Japanese ricefish)Imported
Taxonomic identifieri8090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiNeoteleosteiAcanthomorphataOvalentariaAtherinomorphaeBeloniformesAdrianichthyidaeOryziinaeOryzias

Interactioni

Protein-protein interaction databases

STRINGi8090.ENSORLP00000009823.

Structurei

3D structure databases

ProteinModelPortaliQ764P8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiNOG80379.
HOVERGENiHBG004342.
KOiK03917.

Family and domain databases

Gene3Di2.60.40.10. 3 hits.
3.90.260.10. 1 hit.
InterProiIPR023608. Gln_gamma-glutamylTfrase_euk.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002931. Transglutaminase-like.
IPR008958. Transglutaminase_C.
IPR001102. Transglutaminase_N.
[Graphical view]
PANTHERiPTHR11590. PTHR11590. 1 hit.
PfamiPF00927. Transglut_C. 2 hits.
PF01841. Transglut_core. 1 hit.
PF00868. Transglut_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000459. TGM_EBP42. 1 hit.
SMARTiSM00460. TGc. 1 hit.
[Graphical view]
SUPFAMiSSF49309. SSF49309. 2 hits.
SSF81296. SSF81296. 1 hit.

Sequencei

Sequence statusi: Complete.

Q764P8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDTSATPTS PPAPTPTPSK GNRRGRKAGP ADNSNSEFAN FPEVEYFIAP
60 70 80 90 100
GPRGYPPLTE FLDIWDVDMI RRIDESNKLE HHTELYNSEN LIVRRGQEFQ
110 120 130 140 150
IKLTFNRPYK PDEDKFAVEF TIGSSPQFSK GTYIPVFFTK ERQSSWAGRA
160 170 180 190 200
IANSDNIVTV GITPATNCIV GKYNLYVAVV TPYGVRRQRP DKSREMYILF
210 220 230 240 250
NPWAKDDAVF LDDEMERQEC VMNEMGIIYH GAYNDVAERS WNYGQFNYGV
260 270 280 290 300
LDACLFILDH SEMPIINRGD PVKVTRQASA MMNSQDDNGV LVGDWSGDYI
310 320 330 340 350
YGVSPTSWTG STDILISYAR SKAPVRYAQC WVYAGVFNTF LRCLGIPSRV
360 370 380 390 400
VTNFFSAHDN DGNLKTDIIL DENGKIDKNR TRDSVWNYHC WNECYMSRPD
410 420 430 440 450
LPQGYGGWQI VDATPQETSD GMYRCGPASV HAIKHGEICF PYDAAFVFAE
460 470 480 490 500
VNSDVVFYSR RRDGTLDLVK VNRTHIGRMV LTKAPGEETR RDITSQYKFP
510 520 530 540 550
EGSAEERTVL EKAEEYGCKR VKDNPSLADV DLTLPTLEIS VGDDFELDLE
560 570 580 590 600
FVNHTKEKRT VAAYISGSVV YYTGVPAMSP VQTPHCSNWP QKSVKELVQI
610 620 630 640 650
ESKKYMQHLV EQCNLNFIVT GKIKETGKIV TATKLVTLHN PKLTVEVSGN
660 670 680 690 700
AKVNEEMMVT VEFTNPFSFS LEDVNVRMEG PGVMLPRRKT FSLILGGSHL
710 720 730
TWTELFSPQR PGKTRIIATL DCPSLRQVDG QVSLTVEP
Length:738
Mass (Da):83,154
Last modified:July 4, 2004 - v1
Checksum:i12C913262DC7AFC8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB116366 mRNA. Translation: BAC84967.1.
RefSeqiNP_001098300.1. NM_001104830.1.
UniGeneiOla.6381.

Genome annotation databases

GeneIDi100049464.
KEGGiola:100049464.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB116366 mRNA. Translation: BAC84967.1.
RefSeqiNP_001098300.1. NM_001104830.1.
UniGeneiOla.6381.

3D structure databases

ProteinModelPortaliQ764P8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi8090.ENSORLP00000009823.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi100049464.
KEGGiola:100049464.

Organism-specific databases

CTDi100049464.

Phylogenomic databases

eggNOGiNOG80379.
HOVERGENiHBG004342.
KOiK03917.

Family and domain databases

Gene3Di2.60.40.10. 3 hits.
3.90.260.10. 1 hit.
InterProiIPR023608. Gln_gamma-glutamylTfrase_euk.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002931. Transglutaminase-like.
IPR008958. Transglutaminase_C.
IPR001102. Transglutaminase_N.
[Graphical view]
PANTHERiPTHR11590. PTHR11590. 1 hit.
PfamiPF00927. Transglut_C. 2 hits.
PF01841. Transglut_core. 1 hit.
PF00868. Transglut_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000459. TGM_EBP42. 1 hit.
SMARTiSM00460. TGc. 1 hit.
[Graphical view]
SUPFAMiSSF49309. SSF49309. 2 hits.
SSF81296. SSF81296. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Medaka, Oryzias Latipes embryonic Transglutaminase."
    Koh D., Kudo A., Imai Y., Inohaya K.
    Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ764P8_ORYLA
AccessioniPrimary (citable) accession number: Q764P8
Entry historyi
Integrated into UniProtKB/TrEMBL: July 4, 2004
Last sequence update: July 4, 2004
Last modified: November 25, 2014
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.