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Q76353 (Q76353_9HIV1) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 98. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Interactions·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein names
OrganismHuman immunodeficiency virus 1 EMBL AAC37875.1
Taxonomic identifier11676 [NCBI]
Taxonomic lineageVirusesRetro-transcribing virusesRetroviridaeOrthoretrovirinaeLentivirusPrimate lentivirus group
Virus hostHomo sapiens (Human) [TaxID: 9606]

Protein attributes

Sequence length288 AA.
Sequence statusFragment.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). SAAS SAAS003308

Sequence similarities

Contains 1 integrase-type DNA-binding domain.

Contains RNase H domain. SAAS SAAS003308

Contains integrase catalytic domain. SAAS SAAS003308

Contains integrase-type DNA-binding domain. SAAS SAAS001584

Contains integrase-type zinc finger. SAAS SAAS001584

Contains reverse transcriptase domain. SAAS SAAS003308

Ontologies

Keywords
   Biological processDNA integration SAAS SAAS001037
   DomainZinc-finger SAAS SAAS001584
   LigandChloride PDB 1HYV PDB 3ZSZ PDB 1HYZ PDB 4CF8 PDB 4CES PDB 4CFC PDB 4CGD PDB 4CGG PDB 4CHZ PDB 4CIF PDB 4CJ4 PDB 4CJ5 PDB 4CJE PDB 4CJF PDB 4CJK PDB 4CJL PDB 4CJP PDB 4CJR PDB 4CJS PDB 4CK1
DNA-binding SAAS SAAS001584
Metal-binding
Zinc
   Molecular functionEndonuclease SAAS SAAS003308
Hydrolase
Nuclease
Nucleotidyltransferase
RNA-directed DNA polymerase SAAS SAAS003308
Transferase
   Technical term3D-structure PDB 3ZT4 PDB 3ZCM PDB 4CEE PDB 4CEZ PDB 4CF1 PDB 3ZSO PDB 1HYV PDB 3ZSQ PDB 3ZSR PDB 3ZSV PDB 3ZSW PDB 3ZSX PDB 3ZSY PDB 3ZSZ PDB 3ZT0 PDB 3ZT1 PDB 3ZT2 PDB 1HYZ PDB 4CE9 PDB 4CEA PDB 4CEB PDB 4CEC PDB 4CED PDB 4CF8 PDB 4CEF PDB 4CEO PDB 4CEQ PDB 4CER PDB 4CES PDB 4CF0 PDB 4CF2 PDB 4OVL PDB 4CF9 PDB 3ZT3 PDB 4CFA PDB 4CFB PDB 4CFC PDB 4CFD PDB 4CGD PDB 4CGF PDB 4CGG PDB 4CGH PDB 4CGI PDB 4CGJ PDB 4CHN PDB 4CHO PDB 4CHP PDB 4CHQ PDB 4CHY PDB 4CHZ PDB 4CIE PDB 4CIF PDB 4CIG PDB 4CJ3 PDB 4CJ4 PDB 4CJ5 PDB 4CJE PDB 4CJF PDB 4CJK PDB 4CJL PDB 4CJP PDB 4CJQ PDB 4CJR PDB 4CJS PDB 4CJT PDB 4CJU PDB 4CJV PDB 4CJW PDB 4CK1 PDB 4CK2 PDB 4CK3 PDB 4LH4 PDB 4LH5
Gene Ontology (GO)
   Biological_processDNA integration

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionDNA binding

Inferred from electronic annotation. Source: UniProtKB-KW

RNA-directed DNA polymerase activity

Inferred from electronic annotation. Source: UniProtKB-KW

endonuclease activity

Inferred from electronic annotation. Source: UniProtKB-KW

protein binding

Inferred from physical interaction PubMed 22190034. Source: IntAct

zinc ion binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Binary interactions

With

Entry

#Exp.

IntAct

Notes

HDDC2Q7Z4H32EBI-6248077,EBI-6163836From a different organism.
HEATR1Q9H5833EBI-6248077,EBI-1048716From a different organism.
MCM6Q145662EBI-6248077,EBI-374900From a different organism.
PDIA4P136673EBI-6248077,EBI-1054653From a different organism.
PLAAQ9Y2633EBI-6248077,EBI-1994037From a different organism.
RANBP6O605182EBI-6248077,EBI-1055771From a different organism.
UBA1P223142EBI-6248077,EBI-709688From a different organism.
YWHABP319463EBI-6248077,EBI-359815From a different organism.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Region66 – 672Sulfate 1 binding PDB 3ZT4 PDB 3ZCM PDB 4CEE PDB 4CEZ PDB 4CF1 PDB 3ZSO PDB 3ZSQ PDB 3ZSR PDB 3ZSV PDB 3ZSW PDB 3ZSX PDB 3ZSY PDB 3ZSZ PDB 3ZT0 PDB 3ZT1 PDB 3ZT2 PDB 4CE9 PDB 4CEA PDB 4CEB PDB 4CEC PDB 4CED PDB 4CEF PDB 4CEO PDB 4CEQ PDB 4CER PDB 4CES PDB 4CF0 PDB 4CF2 PDB 4CF9 PDB 3ZT3 PDB 4CFA PDB 4CFC PDB 4CFD PDB 4CGD PDB 4CGF PDB 4CGG PDB 4CGH PDB 4CGI PDB 4CGJ PDB 4CHN PDB 4CHO PDB 4CHP PDB 4CHQ PDB 4CHY PDB 4CIE PDB 4CIG PDB 4CJ4 PDB 4CJ5 PDB 4CJE PDB 4CJF PDB 4CJK PDB 4CJL PDB 4CJP PDB 4CJQ PDB 4CJR PDB 4CJT PDB 4CJU PDB 4CJV PDB 4CJW PDB 4CK1 PDB 4CK2 PDB 4CK3
Region85 – 873Acetate 4 binding PDB 3ZSY PDB 3ZT2 PDB 4CEO PDB 4CEQ PDB 4CF9 PDB 4CFD PDB 4CGF PDB 4CHN PDB 4CHO PDB 4CHP PDB 4CHQ PDB 4CHZ PDB 4CJ4 PDB 4CJ5 PDB 4CJE PDB 4CJF PDB 4CJK PDB 4CJQ PDB 4CJT PDB 4CJU PDB 4CJV PDB 4CK1
Region85 – 873Acetate 5 binding PDB 3ZSZ PDB 4CHO PDB 4CHP PDB 4CJF
Region85 – 873Acetate 6 binding PDB 3ZSZ PDB 3ZT1 PDB 3ZT2 PDB 4CEO PDB 4CEQ PDB 4CF9 PDB 4CFD PDB 4CGF PDB 4CHN PDB 4CHO PDB 4CHP PDB 4CHQ PDB 4CHZ PDB 4CJ4 PDB 4CJ5 PDB 4CJE PDB 4CJF PDB 4CJK PDB 4CJQ PDB 4CJT PDB 4CJU PDB 4CJV PDB 4CK1
Region85 – 873Sulfate 3 binding
Region85 – 873Sulfate 5 binding PDB 3ZCM PDB 4CEE PDB 4CEZ PDB 4CF1 PDB 3ZSO PDB 3ZSR PDB 3ZSW PDB 3ZSX PDB 3ZT1 PDB 4CEA PDB 4CEC PDB 4CED PDB 4CEF PDB 4CER PDB 4CES PDB 4CF0 PDB 4CFA PDB 4CFC PDB 4CGG PDB 4CGJ PDB 4CIE PDB 4CIF PDB 4CIG PDB 4CJ3 PDB 4CJP PDB 4CJQ PDB 4CJR PDB 4CJS PDB 4CJW PDB 4CK1
Region99 – 1035Acetate 4 binding PDB 3ZT2 PDB 4CEO PDB 4CEQ PDB 4CFD PDB 4CGF PDB 4CHN PDB 4CHO PDB 4CHQ PDB 4CHZ PDB 4CJ4 PDB 4CJE PDB 4CJF PDB 4CJK PDB 4CJQ PDB 4CJT PDB 4CJU PDB 4CK1
Region100 – 1078Acetate 5 binding PDB 3ZSZ PDB 4CHO PDB 4CJF
Region100 – 1034Acetate 6 binding PDB 3ZSZ PDB 3ZT1 PDB 3ZT2 PDB 4CEO PDB 4CEQ PDB 4CFD PDB 4CGF PDB 4CHN PDB 4CHO PDB 4CHQ PDB 4CHZ PDB 4CJE PDB 4CJF PDB 4CJK PDB 4CJQ PDB 4CJT PDB 4CJU PDB 4CK1
Region100 – 1034Sulfate 3 binding
Region100 – 1034Sulfate 5 binding PDB 3ZCM PDB 4CEE PDB 4CEZ PDB 4CF1 PDB 3ZSO PDB 3ZSR PDB 3ZSW PDB 3ZSX PDB 3ZT1 PDB 4CEA PDB 4CEC PDB 4CED PDB 4CEF PDB 4CER PDB 4CES PDB 4CF0 PDB 4CFA PDB 4CFC PDB 4CGG PDB 4CGJ PDB 4CIE PDB 4CIF PDB 4CIG PDB 4CJ3 PDB 4CJP PDB 4CJQ PDB 4CJR PDB 4CJS PDB 4CJW PDB 4CK1
Region105 – 1095Sulfate 10 binding PDB 4CK1
Region105 – 1084Sulfate 11 binding PDB 4CK3
Region106 – 1094Acetate 15 binding PDB 4CGF PDB 4CGJ PDB 4CHO PDB 4CIF PDB 4CIG PDB 4CJF PDB 4CJS
Region106 – 1094Acetate 16 binding PDB 4CIG PDB 4CJS
Region107 – 1093Acetate 2 binding PDB 4CIG PDB 4CJS
Region123 – 1253Acetate 18 binding PDB 4CGF
Region123 – 1253Sulfate 10 binding PDB 4CK1
Region123 – 1253Sulfate 13 binding PDB 4CF2 PDB 4CHP
Region123 – 1253Sulfate 7 binding PDB 3ZT4 PDB 4CEE PDB 4CF1 PDB 3ZSO PDB 3ZSY PDB 3ZSZ PDB 3ZT0 PDB 3ZT1 PDB 3ZT2 PDB 4CEO PDB 4CEQ PDB 4CER PDB 4CES PDB 4CF2 PDB 4CF9 PDB 4CFA PDB 4CFB PDB 4CFC PDB 4CFD PDB 4CGG PDB 4CGH PDB 4CGI PDB 4CGJ PDB 4CHP PDB 4CHQ PDB 4CHY PDB 4CHZ PDB 4CIE PDB 4CIF PDB 4CIG PDB 4CJ3 PDB 4CJ4 PDB 4CJ5 PDB 4CJE PDB 4CJK PDB 4CJL PDB 4CJP PDB 4CJQ PDB 4CJR PDB 4CJS PDB 4CJU PDB 4CJW PDB 4CK1 PDB 4CK2 PDB 4CK3
Region123 – 1253Sulfate 8 binding PDB 4CEE PDB 3ZT1 PDB 4CER PDB 4CFA PDB 4CGJ PDB 4CHP PDB 4CK1
Region170 – 1745Sulfate 14 binding PDB 4CHN PDB 4CHO PDB 4CJT
Region171 – 1744Chloride 5 binding PDB 1HYV
Region171 – 1722Sulfate 3 binding PDB 3ZT4 PDB 3ZCM PDB 4CEE PDB 4CEZ PDB 4CF1 PDB 3ZSO PDB 1HYV PDB 3ZSQ PDB 3ZSR PDB 3ZSV PDB 3ZSW PDB 3ZSX PDB 3ZSY PDB 3ZSZ PDB 3ZT0 PDB 3ZT1 PDB 3ZT2 PDB 1HYZ PDB 4CE9 PDB 4CEA PDB 4CEB PDB 4CEC PDB 4CED PDB 4CEF PDB 4CEO PDB 4CEQ PDB 4CER PDB 4CES PDB 4CF0 PDB 4CF2 PDB 4CF9 PDB 3ZT3 PDB 4CFA PDB 4CFC PDB 4CFD PDB 4CGD PDB 4CGF PDB 4CGG PDB 4CGH PDB 4CGI PDB 4CGJ PDB 4CHN PDB 4CHO PDB 4CHP PDB 4CHQ PDB 4CHY PDB 4CIE PDB 4CIG PDB 4CJ4 PDB 4CJ5 PDB 4CJE PDB 4CJF PDB 4CJK PDB 4CJL PDB 4CJP PDB 4CJQ PDB 4CJR PDB 4CJT PDB 4CJU PDB 4CJV PDB 4CJW PDB 4CK1 PDB 4CK2 PDB 4CK3

Sites

Binding site651Chloride 1; via amide nitrogen PDB 4CF8 PDB 4CIF
Binding site671Acetate 1 PDB 4CIG PDB 4CJU PDB 4CK2 PDB 4CK3
Binding site671Sulfate 2 PDB 4CGH
Binding site711Sulfate 3 PDB 3ZT4 PDB 3ZCM PDB 4CEE PDB 4CEZ PDB 4CF1 PDB 3ZSO PDB 1HYV PDB 3ZSQ PDB 3ZSR PDB 3ZSV PDB 3ZSW PDB 3ZSX PDB 3ZSY PDB 3ZSZ PDB 3ZT0 PDB 3ZT1 PDB 3ZT2 PDB 1HYZ PDB 4CE9 PDB 4CEA PDB 4CEB PDB 4CEC PDB 4CED PDB 4CEF PDB 4CEO PDB 4CEQ PDB 4CER PDB 4CES PDB 4CF0 PDB 4CF2 PDB 4CF9 PDB 3ZT3 PDB 4CFA PDB 4CFC PDB 4CFD PDB 4CGD PDB 4CGF PDB 4CGG PDB 4CGH PDB 4CGI PDB 4CGJ PDB 4CHN PDB 4CHO PDB 4CHP PDB 4CHQ PDB 4CHY PDB 4CIE PDB 4CIG PDB 4CJ4 PDB 4CJ5 PDB 4CJE PDB 4CJF PDB 4CJK PDB 4CJL PDB 4CJP PDB 4CJQ PDB 4CJR PDB 4CJT PDB 4CJU PDB 4CJV PDB 4CJW PDB 4CK1 PDB 4CK2 PDB 4CK3
Binding site871Acetate 1 PDB 4CK2
Binding site871Acetate 7 PDB 3ZCM PDB 4CEE PDB 4CF1 PDB 3ZSX PDB 3ZT2 PDB 4CF0 PDB 4CFD PDB 4CGF PDB 4CHZ PDB 4CJ4 PDB 4CJF PDB 4CJK PDB 4CJQ PDB 4CJR PDB 4CJU PDB 4CJV PDB 4CJW PDB 4CK2 PDB 4CK3
Binding site871Acetate 8 PDB 3ZSZ PDB 4CFC PDB 4CIG PDB 4CJL
Binding site871Acetate 9
Binding site871Sulfate 6 PDB 4CJR
Binding site921Acetate 1; via amide nitrogen PDB 4CIG PDB 4CJU PDB 4CK2 PDB 4CK3
Binding site921Chloride 2; via amide nitrogen PDB 4CF8 PDB 4CHZ PDB 4CIF PDB 4CJS PDB 4CK1
Binding site921Chloride 3; via amide nitrogen PDB 4CHZ
Binding site921Sulfate 2; via amide nitrogen PDB 4CGH
Binding site951Acetate 10; via amide nitrogen PDB 4CEC
Binding site951Sulfate 3 PDB 4CHO
Binding site951Sulfate 7 PDB 4CGH PDB 4CJ3 PDB 4CJU
Binding site991Acetate 11 PDB 3ZCM PDB 4CEE PDB 4CF1 PDB 3ZSX PDB 3ZT2 PDB 4CF0 PDB 4CFD PDB 4CGF PDB 4CHZ PDB 4CJ4 PDB 4CJF PDB 4CJK PDB 4CJQ PDB 4CJR PDB 4CJU PDB 4CJV PDB 4CJW PDB 4CK2 PDB 4CK3
Binding site991Acetate 12 PDB 3ZT2 PDB 4CFD PDB 4CJK PDB 4CJU
Binding site991Acetate 8 PDB 3ZSZ PDB 4CFC PDB 4CIG PDB 4CJL
Binding site991Sulfate 9 PDB 4CJR
Binding site1031Acetate 11 PDB 3ZCM PDB 4CEE PDB 4CF1 PDB 3ZSX PDB 3ZT2 PDB 4CF0 PDB 4CFD PDB 4CGF PDB 4CHZ PDB 4CJ4 PDB 4CJF PDB 4CJK PDB 4CJQ PDB 4CJR PDB 4CJU PDB 4CJV PDB 4CJW PDB 4CK2 PDB 4CK3
Binding site1031Acetate 12 PDB 3ZT2 PDB 4CFD PDB 4CJU
Binding site1031Acetate 8 PDB 3ZSZ PDB 4CFC PDB 4CIG PDB 4CJL
Binding site1031Sulfate 6 PDB 4CJR
Binding site1031Sulfate 9 PDB 4CJR
Binding site1071Acetate 12 PDB 3ZT2 PDB 4CJK
Binding site1071Acetate 13; via carbonyl oxygen PDB 4CF1
Binding site1071Acetate 17 PDB 3ZT1 PDB 4CEO PDB 4CHN PDB 4CJE PDB 4CJU
Binding site1071Acetate 4 PDB 4CHO PDB 4CJ5 PDB 4CJT
Binding site1071Acetate 6 PDB 4CHO PDB 4CJ5 PDB 4CJT
Binding site1071Sulfate 12 PDB 4CJP PDB 4CJQ
Binding site1071Sulfate 3 PDB 4CEE
Binding site1071Sulfate 5 PDB 3ZCM PDB 4CEZ PDB 4CF1 PDB 3ZSO PDB 3ZSR PDB 3ZSW PDB 3ZSX PDB 4CEA PDB 4CEC PDB 4CED PDB 4CEF PDB 4CES PDB 4CF0 PDB 4CFC PDB 4CGG PDB 4CGJ PDB 4CIE PDB 4CIF PDB 4CIG PDB 4CJ3 PDB 4CJR PDB 4CJS PDB 4CJW
Binding site1071Sulfate 7 PDB 4CEE PDB 4CER PDB 4CFA PDB 4CK1
Binding site1071Sulfate 8 PDB 4CEE PDB 3ZT1 PDB 4CER PDB 4CFA PDB 4CK1
Binding site1251Acetate 10 PDB 4CEC
Binding site1591Sulfate 1 PDB 3ZT4 PDB 3ZCM PDB 4CEE PDB 4CEZ PDB 4CF1 PDB 3ZSO PDB 3ZSQ PDB 3ZSR PDB 3ZSV PDB 3ZSW PDB 3ZSX PDB 3ZSY PDB 3ZSZ PDB 3ZT0 PDB 3ZT1 PDB 3ZT2 PDB 4CE9 PDB 4CEA PDB 4CEB PDB 4CEC PDB 4CED PDB 4CEF PDB 4CEO PDB 4CEQ PDB 4CER PDB 4CES PDB 4CF0 PDB 4CF2 PDB 4CF9 PDB 3ZT3 PDB 4CFA PDB 4CFC PDB 4CFD PDB 4CGD PDB 4CGF PDB 4CGG PDB 4CGH PDB 4CGI PDB 4CGJ PDB 4CHN PDB 4CHO PDB 4CHP PDB 4CHQ PDB 4CHY PDB 4CIE PDB 4CIG PDB 4CJ4 PDB 4CJ5 PDB 4CJE PDB 4CJF PDB 4CJK PDB 4CJL PDB 4CJP PDB 4CJQ PDB 4CJR PDB 4CJT PDB 4CJU PDB 4CJV PDB 4CJW PDB 4CK1 PDB 4CK2 PDB 4CK3
Binding site1661Sulfate 3 PDB 4CF9 PDB 4CHN
Binding site1721Sulfate 15; via amide nitrogen PDB 4CFA PDB 4CJT
Binding site1841Acetate 15; via carbonyl oxygen PDB 4CGF
Binding site1841Acetate 16; via carbonyl oxygen PDB 4CIG
Binding site1841Sulfate 4; via carbonyl oxygen PDB 4CK1
Binding site1971Acetate 2; via carbonyl oxygen PDB 4CIG PDB 4CJS

Experimental info

Non-terminal residue11 EMBL AAC37875.1

Sequences

Sequence LengthMass (Da)Tools
Q76353 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: 0680E5CD1E201580

FASTA28832,199
        10         20         30         40         50         60 
FLDGIDKAQE EHEKYHSNWR AMASDFNLPP VVAKEIVASC DKCQLKGEAM HGQVDCSPGI 

        70         80         90        100        110        120 
WQLDCTHLEG KVILVAVHVA SGYIEAEVIP AETGQETAYF LLKLAGRWPV KTVHTDNGSN 

       130        140        150        160        170        180 
FTSTTVKAAC WWAGIKQEFG IPYNPQSQGV IESMNKELKK IIGQVRDQAE HLKTAVQMAV 

       190        200        210        220        230        240 
FIHNFKRKGG IGGYSAGERI VDIIATDIQT KELQKQITKI QNFRVYYRDS RDPVWKGPAK 

       250        260        270        280 
LLWKGEGAVV IQDNSDIKVV PRRKAKIIRD YGKQMAGDDC VASRQDED 

« Hide

References

[1]"HIV1 integrase expressed in Escherichia coli from a synthetic gene."
Holler T.P., Foltin S.K., Ye Q.Z., Hupe D.J.
Gene 136:323-328(1993) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: NY5 EMBL AAC37875.1.
[2]"Identification of a small-molecule binding site at the dimer interface of the HIV integrase catalytic domain."
Molteni V., Greenwald J., Rhodes D., Hwang Y., Kwiatkowski W., Bushman F.D., Siegel J.S., Choe S.
Acta Crystallogr. D 57:536-544(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (1.70 ANGSTROMS) OF 47-212 IN COMPLEX WITH CHLORIDE AND SULFATE.
[3]"Small molecule inhibitors of the LEDGF site of human immunodeficiency virus integrase identified by fragment screening and structure based design."
Peat T.S., Rhodes D.I., Vandegraaff N., Le G., Smith J.A., Clark L.J., Jones E.D., Coates J.A., Thienthong N., Newman J., Dolezal O., Mulder R., Ryan J.H., Savage G.P., Francis C.L., Deadman J.J.
PLoS ONE 7:e40147-e40147(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (1.70 ANGSTROMS) OF 56-212 IN COMPLEX WITH ACETATE AND SULFATE.
[4]"Dual inhibition of HIV-1 replication by integrase-LEDGF allosteric inhibitors is predominant at the post-integration stage."
Le Rouzic E., Bonnard D., Chasset S., Bruneau J.M., Chevreuil F., Le Strat F., Nguyen J., Beauvoir R., Amadori C., Brias J., Vomscheid S., Eiler S., Levy N., Delelis O., Deprez E., Saib A., Zamborlini A., Emiliani S. expand/collapse author list , Ruff M., Ledoussal B., Moreau F., Benarous R.
Retrovirology 10:144-144(2013) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (1.80 ANGSTROMS) OF 50-212.
[5]"Interrogating HIV integrase for compounds that bind- a SAMPL challenge."
Peat T.S., Dolezal O., Newman J., Mobley D., Deadman J.J.
J. Comput. Aided Mol. Des. 0:0-0(2014) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (1.65 ANGSTROMS) OF 50-212 IN COMPLEX WITH ACETATE; CHLORIDE AND SULFATE.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L21188 Unassigned RNA. Translation: AAC37875.1.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1HYVX-ray1.70A47-212[»]
1HYZX-ray2.30A47-212[»]
3ZCMX-ray1.80A/B56-212[»]
3ZSOX-ray1.75A/B56-212[»]
3ZSQX-ray1.70A/B56-212[»]
3ZSRX-ray1.70A/B56-212[»]
3ZSVX-ray1.75A/B56-212[»]
3ZSWX-ray1.80A/B56-212[»]
3ZSXX-ray1.95A/B56-212[»]
3ZSYX-ray2.20A/B56-212[»]
3ZSZX-ray2.00A/B56-212[»]
3ZT0X-ray1.95A/B56-212[»]
3ZT1X-ray1.75A/B56-212[»]
3ZT2X-ray1.70A/B56-212[»]
3ZT3X-ray1.95A/B56-212[»]
3ZT4X-ray2.20A/B56-212[»]
4CE9X-ray2.10A/B50-212[»]
4CEAX-ray1.80A/B50-212[»]
4CEBX-ray1.75A/B50-212[»]
4CECX-ray1.75A/B50-212[»]
4CEDX-ray1.75A/B50-212[»]
4CEEX-ray1.80A/B50-212[»]
4CEFX-ray1.70A/B50-212[»]
4CEOX-ray1.90A/B50-212[»]
4CEQX-ray1.70A/B50-212[»]
4CERX-ray1.70A/B50-212[»]
4CESX-ray1.85A/B50-212[»]
4CEZX-ray1.70A/B50-212[»]
4CF0X-ray1.85A/B50-212[»]
4CF1X-ray1.95A/B50-212[»]
4CF2X-ray1.95A/B50-212[»]
4CF8X-ray1.65A/B50-212[»]
4CF9X-ray2.10A/B50-212[»]
4CFAX-ray2.05A/B50-212[»]
4CFBX-ray1.95A/B50-212[»]
4CFCX-ray1.90A/B50-212[»]
4CFDX-ray2.15A/B50-212[»]
4CGDX-ray2.00A/B50-212[»]
4CGFX-ray1.70A/B50-212[»]
4CGGX-ray1.75A/B50-212[»]
4CGHX-ray1.76A/B50-212[»]
4CGIX-ray2.07A/B50-212[»]
4CGJX-ray2.15A/B50-212[»]
4CHNX-ray2.00A/B50-212[»]
4CHOX-ray1.70A/B50-212[»]
4CHPX-ray1.90A/B50-212[»]
4CHQX-ray1.95A/B50-212[»]
4CHYX-ray1.70A/B50-212[»]
4CHZX-ray1.80A/B50-212[»]
4CIEX-ray1.70A/B50-212[»]
4CIFX-ray1.80A/B50-212[»]
4CIGX-ray1.70A/B50-212[»]
4CJ3X-ray1.70A/B50-212[»]
4CJ4X-ray1.80A/B50-212[»]
4CJ5X-ray1.95A/B50-212[»]
4CJEX-ray1.90A/B50-212[»]
4CJFX-ray1.90A/B50-212[»]
4CJKX-ray1.75A/B50-212[»]
4CJLX-ray1.77A50-212[»]
4CJPX-ray2.00A/B50-212[»]
4CJQX-ray1.70A/B50-212[»]
4CJRX-ray1.80A/B50-212[»]
4CJSX-ray1.80A/B50-212[»]
4CJTX-ray1.71A/B50-212[»]
4CJUX-ray1.70A/B50-212[»]
4CJVX-ray1.95A/B50-212[»]
4CJWX-ray1.95A/B50-212[»]
4CK1X-ray1.75A/B50-212[»]
4CK2X-ray1.85A/B50-212[»]
4CK3X-ray1.79A/B50-212[»]
4LH4X-ray1.80A50-212[»]
4LH5X-ray2.19A50-212[»]
4OVLX-ray1.70A/B50-212[»]
ProteinModelPortalQ76353.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

IntActQ76353. 25 interactions.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D1.10.10.200. 1 hit.
2.30.30.10. 1 hit.
3.30.420.10. 1 hit.
InterProIPR001037. Integrase_C_retrovir.
IPR001584. Integrase_cat-core.
IPR017856. Integrase_Zn-bd_dom-like_N.
IPR003308. Integrase_Zn-bd_dom_N.
IPR012337. RNaseH-like_dom.
[Graphical view]
PfamPF00552. IN_DBD_C. 1 hit.
PF02022. Integrase_Zn. 1 hit.
PF00665. rve. 1 hit.
[Graphical view]
SUPFAMSSF46919. SSF46919. 1 hit.
SSF50122. SSF50122. 1 hit.
SSF53098. SSF53098. 1 hit.
PROSITEPS50994. INTEGRASE. 1 hit.
PS51027. INTEGRASE_DBD. 1 hit.
PS50876. ZF_INTEGRASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

EvolutionaryTraceQ76353.

Entry information

Entry nameQ76353_9HIV1
AccessionPrimary (citable) accession number: Q76353
Entry history
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: June 11, 2014
This is version 98 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)