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Protein
Submitted name:

ATP7A protein

Gene

ATP7A

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi19PROSITE-ProRule annotation1
Metal bindingi22PROSITE-ProRule annotation1
Metal bindingi182PROSITE-ProRule annotation1
Metal bindingi185PROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandMetal-bindingPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
ATP7A proteinImported
Gene namesi
Name:ATP7AImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000165240.17.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA72.

PTM / Processingi

Proteomic databases

MaxQBiQ762B6.
PaxDbiQ762B6.
PeptideAtlasiQ762B6.
PRIDEiQ762B6.

Expressioni

Gene expression databases

BgeeiENSG00000165240.
GenevisibleiQ762B6. HS.

Structurei

3D structure databases

ProteinModelPortaliQ762B6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini9 – 75HMAInterPro annotationAdd BLAST67
Domaini172 – 238HMAInterPro annotationAdd BLAST67

Phylogenomic databases

eggNOGiKOG0207. Eukaryota.
COG2217. LUCA.
HOVERGENiHBG065948.
KOiK17686.

Family and domain databases

CDDicd00371. HMA. 2 hits.
InterProiView protein in InterPro
IPR017969. Heavy-metal-associated_CS.
IPR006122. HMA_Cu_ion-bd.
IPR006121. HMA_dom.
IPR036163. HMA_dom_sf.
PfamiView protein in Pfam
PF00403. HMA. 2 hits.
SUPFAMiSSF55008. SSF55008. 2 hits.
TIGRFAMsiTIGR00003. TIGR00003. 2 hits.
PROSITEiView protein in PROSITE
PS01047. HMA_1. 2 hits.
PS50846. HMA_2. 2 hits.

Sequencei

Sequence statusi: Complete.

Q762B6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDPSMGVNSV TISVEGMTCN SCVWTIEQQI GKVNGVHHIK VSLEEKNATI
60 70 80 90 100
IYDPKLQTPK TLQEAIDDMG FDAVIHNPDP LPVLTDTLFL TVTASLTLPW
110 120 130 140 150
DHIQSTLLKT KGVTDIKIYP QKRTVAVTII PSIVNANQIK ELVPELSLDT
160 170 180 190 200
GTLEKKSGAC EDHSMAQAGE VVLKMKVEGM TCHSCTSTIE GKIGKLQGVQ
210 220 230 240 250
RIKVSLDNQE ATIVYQPHLI SVEEMKKQIE AMGFPAFVKK QPKYLKLGAI
260 270
DVERLKNTPV KSSEGSQQRS PSYQ
Length:274
Mass (Da):30,124
Last modified:July 5, 2004 - v1
Checksum:i1233AE33CD302122
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB117973 mRNA. Translation: BAC82353.1.
RefSeqiNP_000043.4. NM_000052.6.
NP_001269153.1. NM_001282224.1.
UniGeneiHs.496414.
Hs.733232.

Genome annotation databases

GeneIDi538.
KEGGihsa:538.
UCSCiuc065abx.1. human.

Entry informationi

Entry nameiQ762B6_HUMAN
AccessioniPrimary (citable) accession number: Q762B6
Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: October 25, 2017
This is version 83 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.