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Unreviewed, UniProtKB/TrEMBL Q761V2 (Q761V2_HUMAN)

Last modified January 19, 2010. Version 38. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information

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Names and origin

Protein namesSubmitted name:
    P53 EMBL BAD11806.1
Submitted name:
    Tumor protein p53 EMBL ABM69023.1
Gene names
Name: p53 EMBL BAD11806.1
Synonyms: TP53 EMBL ABM69023.1
OrganismHomo sapiens (Human) EMBL BAD11806.1
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

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Protein attributes

Sequence length61 AA.
Sequence statusFragment.
Protein existenceEvidence at transcript level.

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Ontologies

Gene Ontology (GO)
   Biological processB cell lineage commitment

Inferred from electronic annotation. Source: Compara

DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis

Inferred from electronic annotation. Source: Compara

G1/S DNA damage checkpoint

Inferred from electronic annotation. Source: Compara

T cell differentiation in the thymus

Inferred from electronic annotation. Source: Compara

T cell lineage commitment

Inferred from electronic annotation. Source: Compara

T cell proliferation during immune response

Inferred from electronic annotation. Source: Compara

cell aging

Inferred from electronic annotation. Source: Compara

cellular response to UV

Inferred from electronic annotation. Source: Compara

central nervous system development

Inferred from electronic annotation. Source: Compara

chromosome organization

Inferred from electronic annotation. Source: Compara

double-strand break repair

Inferred from electronic annotation. Source: Compara

gastrulation

Inferred from electronic annotation. Source: Compara

in utero embryonic development

Inferred from electronic annotation. Source: Compara

negative regulation of DNA replication

Inferred from electronic annotation. Source: Compara

negative regulation of apoptosis

Inferred from electronic annotation. Source: Compara

negative regulation of fibroblast proliferation

Inferred from electronic annotation. Source: Compara

negative regulation of neuroblast proliferation

Inferred from electronic annotation. Source: Compara

negative regulation of transcription from RNA polymerase II promoter

Inferred from electronic annotation. Source: Compara

positive regulation of neuron apoptosis

Inferred from electronic annotation. Source: Compara

positive regulation of transcription from RNA polymerase II promoter

Inferred from electronic annotation. Source: Compara

protein import into nucleus, translocation

Inferred from electronic annotation. Source: Compara

rRNA transcription

Inferred from electronic annotation. Source: Compara

regulation of mitochondrial membrane permeability

Inferred from electronic annotation. Source: Compara

release of cytochrome c from mitochondria

Inferred from electronic annotation. Source: Compara

response to X-ray

Inferred from electronic annotation. Source: Compara

response to drug

Inferred from electronic annotation. Source: Compara

response to gamma radiation

Inferred from electronic annotation. Source: Compara

response to salt stress

Inferred from electronic annotation. Source: Compara

   Cellular componentcytosol

Inferred from electronic annotation. Source: Compara

nucleus

Inferred from electronic annotation. Source: Compara

replication fork

Inferred from electronic annotation. Source: Compara

   Molecular functionprotein binding

Inferred from physical interaction. Source: UniProtKB

transcription factor activity

Inferred from electronic annotation. Source: Compara

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Experimental info

Non-terminal residue11 EMBL BAD11806.1
Non-terminal residue611 EMBL BAD11806.1

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Sequences

Sequence LengthMass (Da)Tools
Q761V2-1 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: F130CCC26B24312F

FASTA617,003
        10         20         30         40         50         60 
YSPALNKMFC QLAKTCPVQL WVDSTPPPGT RVRAMAIYKQ SQHMTEVVRR CPHHERCSDS 


D

« Hide

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References

[1]"In vitro establishment of tumorigenic human B-lymphoblastoid cell lines transformed by Epstein-Barr virus."
Takahashi T., Kawabe T., Okazaki Y., Ito C., Noda K., Tajima M., Satoh M., Goto M., Mitsui Y., Tahara H., Ide T., Furuichi Y., Sugimoto M.
Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
[2]"Sequence of exon 5 of p53 gene from lung tissue biopsy belongs to 12 patients who were exposed to mustard gas."
Karami A., Biramijamal F., Arjmand S., Ghanei M., Eshraghi M.
Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Tissue: Lung biopsy EMBL ABM69023.1.
[3]"Detection of p53 mutation in esophageal carcinoma."
Silveira A.P.F., Manoel-Caetano F.S., Aoki S.M., Rahal P., Silva A.E.
Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Tissue: Esophageal squamous cell carcinoma EMBL ACA63978.1.
+Additional computationally mapped references.

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ		EF178467 Genomic DNA. Translation: ABM69023.1.
EU523098 Genomic DNA. Translation: ACA63978.1.
AB118156 Genomic DNA. Translation: BAD11806.1.
IPIIPI00796188.
UniGeneHs.654481

3D structure databases

SMRQ761V2. Positions 1-61.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ761V2.

Genome annotation databases

EnsemblENST00000269305; ENSP00000269305; ENSG00000141510; Homo sapiens. [Genome view]
ENST00000359597; ENSP00000352610; ENSG00000141510; Homo sapiens. [Genome view]
ENST00000396473; ENSP00000379735; ENSG00000141510; Homo sapiens. [Genome view]
ENST00000413465; ENSP00000410739; ENSG00000141510; Homo sapiens. [Genome view]
ENST00000414315; ENSP00000394195; ENSG00000141510; Homo sapiens. [Genome view]
ENST00000419024; ENSP00000402130; ENSG00000141510; Homo sapiens. [Genome view]
ENST00000420246; ENSP00000391127; ENSG00000141510; Homo sapiens. [Genome view]
ENST00000445888; ENSP00000391478; ENSG00000141510; Homo sapiens. [Genome view]
ENST00000455263; ENSP00000398846; ENSG00000141510; Homo sapiens. [Genome view]

Organism-specific databases

HGNCHGNC:11998. TP53.
GenAtlasSearch...

Phylogenomic databases

HOVERGENQ761V2.

Gene expression databases

ArrayExpressQ761V2.
BgeeQ761V2.

Family and domain databases

InterProIPR008967. p53-like_TF_DNA-bd.
IPR012346. p53/RUNT-type_TF_DNA_bd.
IPR011615. p53_DNA_bd.
IPR015551. Trp53.
[Graphical view]
Gene3DG3DSA:2.60.40.720. p53_RUNT_DNA_bd. 1 hit.
PANTHERPTHR11447. Trp53. 1 hit.
PfamPF00870. P53. 1 hit.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry nameQ761V2_HUMAN
AccessionPrimary (citable) accession number: Q761V2
Entry history
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: January 19, 2010
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
Names and origin · Protein attributes · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information