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Q760R9 (RBL_PYRKA) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 46. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ribulose bisphosphate carboxylase large chain

Short name=RuBisCO large subunit
EC=4.1.1.39
Gene names
Name:rbcL
Encoded onPlastid; Chloroplast
OrganismPyropia katadae (Red alga) (Porphyra katadae)
Taxonomic identifier76161 [NCBI]
Taxonomic lineageEukaryotaRhodophytaBangiophyceaeBangialesBangiaceaePyropia

Protein attributes

Sequence length488 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process. Both reactions occur simultaneously and in competition at the same active site By similarity. HAMAP-Rule MF_01338

Catalytic activity

2 3-phospho-D-glycerate + 2 H+ = D-ribulose 1,5-bisphosphate + CO2 + H2O. HAMAP-Rule MF_01338

3-phospho-D-glycerate + 2-phosphoglycolate = D-ribulose 1,5-bisphosphate + O2. HAMAP-Rule MF_01338

Cofactor

Binds 1 magnesium ion per subunit By similarity. HAMAP-Rule MF_01338

Subunit structure

Heterohexadecamer of 8 large chains and 8 small chains By similarity.

Subcellular location

Plastidchloroplast HAMAP-Rule MF_01338.

Miscellaneous

The basic functional RuBisCO is composed of a large chain homodimer in a "head-to-tail" conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric "cap" on each end of the "barrel" By similarity.

Sequence similarities

Belongs to the RuBisCO large chain family. Type I subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 488488Ribulose bisphosphate carboxylase large chain HAMAP-Rule MF_01338
PRO_0000277428

Sites

Active site1791Proton acceptor By similarity
Active site2971Proton acceptor By similarity
Metal binding2051Magnesium; via carbamate group By similarity
Metal binding2071Magnesium By similarity
Metal binding2081Magnesium By similarity
Binding site1271Substrate; in homodimeric partner By similarity
Binding site1771Substrate By similarity
Binding site1811Substrate By similarity
Binding site2981Substrate By similarity
Binding site3301Substrate By similarity
Binding site3821Substrate By similarity
Site3371Transition state stabilizer By similarity

Amino acid modifications

Modified residue2051N6-carboxylysine By similarity

Sequences

Sequence LengthMass (Da)Tools
Q760R9 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: C1847D0EA11284DC

FASTA48854,060
        10         20         30         40         50         60 
MSQSVESRTR IKSERYESGV IPYAKMGYWD ADYVIKETDI LALFRITPQP GVDPIEASAA 

        70         80         90        100        110        120 
IAGESSTATW TVVWTDLLTA CDLYRAKAYR VDPVPNVADQ YFAYIAYDID LFEEGSIANL 

       130        140        150        160        170        180 
TASIIGNVFG FKAVKALRLE DMRMPVAYLK TFQGPATGLI VERERMDKFG RPFLGATVKP 

       190        200        210        220        230        240 
KLGLSGKNYG RVVYEGLKGG LDFLKDDENI NSQPFMRWRE RFLYSMEGVN KASASAGEIK 

       250        260        270        280        290        300 
GHYLNVTAAT MEDMYERAEF SKEVGSIICM IDLVIGYTAI QSMAIWARKH DMILHLHRAG 

       310        320        330        340        350        360 
NSTYSRQKNH GMNFRVICKW MRMAGVDHIH AGTVVGKLEG DPLMIKGFYN TLLESDTDIN 

       370        380        390        400        410        420 
LPQGLFFAQN WASLRKVVPV ASGGIHAGQM HQLLDYLGDD VVLQFGGGTI GHPDGIQAGA 

       430        440        450        460        470        480 
TANRVALESM VMARNEGRNY VAEGPQILRD AAKTCGPLQT ALDLWKDISF NYTSTDTADF 


VETPTANI 

« Hide

References

[1]"Species determination utilizing Porphyra (Rhodophyta) plastid DNA RuBisCo sequences."
Kito H., Kunimoto M., Mizukami Y., Murase N., Kuroki T., Taruta M., Levine I.
Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Tissue: Thallus.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AB118583 Genomic DNA. Translation: BAC84933.1.

3D structure databases

ProteinModelPortalQ760R9.
SMRQ760R9. Positions 9-481.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D3.20.20.110. 1 hit.
3.30.70.150. 1 hit.
HAMAPMF_01338. RuBisCO_L_type1.
InterProIPR020878. RuBisCo_large_chain_AS.
IPR020888. RuBisCO_lsu.
IPR000685. RuBisCO_lsu_C.
IPR017443. RuBisCO_lsu_fd_N.
IPR017444. RuBisCO_lsu_N.
[Graphical view]
PfamPF00016. RuBisCO_large. 1 hit.
PF02788. RuBisCO_large_N. 1 hit.
[Graphical view]
SUPFAMSSF51649. SSF51649. 1 hit.
SSF54966. SSF54966. 1 hit.
PROSITEPS00157. RUBISCO_LARGE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameRBL_PYRKA
AccessionPrimary (citable) accession number: Q760R9
Entry history
Integrated into UniProtKB/Swiss-Prot: February 6, 2007
Last sequence update: July 5, 2004
Last modified: February 19, 2014
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families