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Protein

Probable trehalose-phosphate phosphatase 1

Gene

TPP1

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Removes the phosphate from trehalose 6-phosphate to produce free trehalose. Trehalose accumulation in plant improves abiotic stress tolerance.3 Publications

Miscellaneous

Over-expression of TPP1 increases trehalose levels and enhances tolerance to salt and cold stresses.1 Publication

Catalytic activityi

Trehalose 6-phosphate + H2O = trehalose + phosphate.2 Publications

Cofactori

Kineticsi

  1. KM=92.1 µM for trehalose 6-phosphate1 Publication

    pH dependencei

    Optimum pH is 6.5-7.0.1 Publication

    Pathwayi: trehalose biosynthesis

    This protein is involved in the pathway trehalose biosynthesis, which is part of Glycan biosynthesis.
    View all proteins of this organism that are known to be involved in the pathway trehalose biosynthesis and in Glycan biosynthesis.

    GO - Molecular functioni

    • trehalose-phosphatase activity Source: UniProtKB

    GO - Biological processi

    • response to cold Source: UniProtKB
    • response to salt stress Source: UniProtKB
    • trehalose biosynthetic process Source: UniProtKB

    Keywordsi

    Molecular functionHydrolase
    Biological processStress response

    Enzyme and pathway databases

    BRENDAi3.1.3.12 4460
    UniPathwayiUPA00299

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable trehalose-phosphate phosphatase 1 (EC:3.1.3.12)
    Short name:
    OsTPP1
    Alternative name(s):
    Trehalose 6-phosphate phosphatase
    Gene namesi
    Name:TPP1
    Ordered Locus Names:Os02g0661100, LOC_Os02g44230
    ORF Names:OsJ_07820, P0516F12.9, P0708H12.35
    OrganismiOryza sativa subsp. japonica (Rice)
    Taxonomic identifieri39947 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryzaOryza sativa
    Proteomesi
    • UP000059680 Componenti: Chromosome 2

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    ChainiPRO_00004176531 – 371Probable trehalose-phosphate phosphatase 1Add BLAST371

    Proteomic databases

    PaxDbiQ75WV3

    Expressioni

    Tissue specificityi

    Expressed in roots and shoots.1 Publication

    Inductioni

    By cold, drought, salt stress and abscisic acid (ABA).3 Publications

    Gene expression databases

    ExpressionAtlasiQ75WV3 differential
    GenevisibleiQ75WV3 OS

    Interactioni

    Protein-protein interaction databases

    STRINGi39947.LOC_Os02g44230.1

    Structurei

    3D structure databases

    ProteinModelPortaliQ75WV3
    SMRiQ75WV3
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the trehalose phosphatase family.Curated

    Phylogenomic databases

    eggNOGiENOG410IMM9 Eukaryota
    COG1877 LUCA
    InParanoidiQ75WV3
    KOiK01087
    OMAiGMDIMAS
    OrthoDBiEOG09360DNK

    Family and domain databases

    Gene3Di3.40.50.1000, 2 hits
    InterProiView protein in InterPro
    IPR036412 HAD-like_sf
    IPR006379 HAD-SF_hydro_IIB
    IPR023214 HAD_sf
    IPR003337 Trehalose_PPase
    PfamiView protein in Pfam
    PF02358 Trehalose_PPase, 1 hit
    SUPFAMiSSF56784 SSF56784, 1 hit
    TIGRFAMsiTIGR01484 HAD-SF-IIB, 1 hit
    TIGR00685 T6PP, 1 hit

    Sequencei

    Sequence statusi: Complete.

    Q75WV3-1 [UniParc]FASTAAdd to basket

    « Hide

            10         20         30         40         50
    MDLSNSSPVI TDPVAISQQL LGGLPSNLMQ FSVMPGGYSS SGMNVGVSRL
    60 70 80 90 100
    KIEEVLVNGL LDAMKSSSPR RRLNVAFGED NSSEEEDPAY SAWMAKCPSA
    110 120 130 140 150
    LASFKQIVAS AQGKKIAVFL DYDGTLSPIV DDPDKAVMSP VMRAAVRNVA
    160 170 180 190 200
    KYFPTAIVSG RSRNKVFEFV KLKELYYAGS HGMDIMAPSA NHEHSAEKSK
    210 220 230 240 250
    QANLFQPAHD FLPMIDEVTK SLLQVVSGIE GATVENNKFC VSVHYRNVAE
    260 270 280 290 300
    KDWKLVARLV NEVLEAFPRL KVTNGRMVLE VRPVIDWDKG KAVEFLLQSL
    310 320 330 340 350
    GLNDSENVIP IYIGDDRTDE DAFKVLRQRN CGYGILVSQV PKETEAFYSL
    360 370
    RDPSEVMEFL NFLVRWKKHS V
    Length:371
    Mass (Da):41,128
    Last modified:July 5, 2004 - v1
    Checksum:i9F518916127CCD34
    GO

    Sequence databases

    Select the link destinations:
    EMBLi
    GenBanki
    DDBJi
    Links Updated
    AB120515 mRNA Translation: BAD12596.1
    AP004883 Genomic DNA Translation: BAD25622.1
    AP005072 Genomic DNA Translation: BAD25753.1
    AP008208 Genomic DNA Translation: BAF09559.1
    AP014958 Genomic DNA Translation: BAS80139.1
    CM000139 Genomic DNA Translation: EEE57517.1
    AK103391 mRNA Translation: BAG96056.1
    RefSeqiXP_015623255.1, XM_015767769.1
    UniGeneiOs.6092

    Genome annotation databases

    EnsemblPlantsiOs02t0661100-01; Os02t0661100-01; Os02g0661100
    GeneIDi4330221
    GrameneiOs02t0661100-01; Os02t0661100-01; Os02g0661100
    KEGGiosa:4330221

    Similar proteinsi

    Entry informationi

    Entry nameiTPP1_ORYSJ
    AccessioniPrimary (citable) accession number: Q75WV3
    Secondary accession number(s): A0A0P0VMN9
    Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 13, 2012
    Last sequence update: July 5, 2004
    Last modified: May 23, 2018
    This is version 84 of the entry and version 1 of the sequence. See complete history.
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. Oryza sativa (rice)
      Index of Oryza sativa entries and their corresponding gene designations
    3. SIMILARITY comments
      Index of protein domains and families

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