Q75VJ8 (Q75VJ8_TOBAC) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: Ubiquitin activating enzyme 2 EMBL BAD00984.1
Organism	Nicotiana tabacum (Common tobacco) EMBL BAD00984.1
Taxonomic identifier	4097 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › asterids › lamiids › Solanales › Solanaceae › Nicotianoideae › Nicotianeae › Nicotiana

Protein attributes

Sequence length	1080 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Sequence similarities

Belongs to the ubiquitin-activating E1 family. RuleBase RU000519

Ontologies

Keywords
Biological process	Ubl conjugation pathway RuleBase RU000519
Ligand	ATP-binding RuleBase RU000519 Nucleotide-binding
Molecular function	Ligase RuleBase RU000519
Gene Ontology (GO)
Biological_process	cellular protein modification process Inferred from electronic annotation. Source: InterPro
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ligase activity Inferred from electronic annotation. Source: UniProtKB-KW small protein activating enzyme activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q75VJ8 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: 4E699DEEB6FDD7C7	FASTA	1,080	120,207
	10 20 30 40 50 60 MLPVKRTVEV GGENDDVSVD PLTKKHKATA AASGDSSTVT MGGTGSATTG DVNTNGNATN 70 80 90 100 110 120 GKSPIDARNS PDIDEDLHSR QLAVYGRETM RRLFASNVLV SGLQGLGAEI AKNLILAGVK 130 140 150 160 170 180 SVTLHDEGNV ELWDLSSNFI FTEEDVGKNR ALASIQKLQE LNNAVIISTL TDALTKEQLS 190 200 210 220 230 240 NFQAVVFTDI SLEKAVEFDD YCHKHQPPIA FIKAEVRGLF GSVFCDFGPE FTVADVDGED 250 260 270 280 290 300 PHTGIIASIS NDNPALVGCI DDERLEFEDG DLVIFSEVRG MTELNDGKPR KIKNARPYSF 310 320 330 340 350 360 TIEEDTSNYA AYERGGIVTQ VKEPKVLKFK PLREAIKDPG DFLLSDFSKF DRPPILHLAF 370 380 390 400 410 420 QALDRFVSES GRFPLAGSEE DAQRLISFVT DLNNSLSDGK LEEIDQKLLR NFAFGARAVL 430 440 450 460 470 480 NPMAAMFGGI VGQEVVKACS GKFHPLYQFF YFDSVESLPT APLDXNDLKP LNSRYDAQIS 490 500 510 520 530 540 VFGNKLQKKL EEAKVFVVGS GALGCEFLKN LALMGVCCGD KGKLTITDDD VIEKSNLSRQ 550 560 570 580 590 600 FLFRDWNIGQ AKSTVAAAAA SLINPRIHIE ALQNRASPET ESVFDDTFWE NLSVVINALD 610 620 630 640 650 660 NVNARLYIDQ RCLYFQKPLL ESGTLGAKCN TQMVIPHLTE NYGASRDPPE KQAPMCTVHS 670 680 690 700 710 720 FPHNIDHCLT WARSEFEGLL EKTPTEVNAY LINPSDYISA MQKAGDAQAR DTLDRVLECL 730 740 750 760 770 780 DKERCDTFQD CITWARLRFE DYFADRVKQL TFTFPEEATT SSGAPFWSAP KRFPRPLQFS 790 800 810 820 830 840 VDDASHLQFL LAASILRAET FGILIPDWVK SPQKLAEAVD KVIVPDFQPK KDVKIVTDEK 850 860 870 880 890 900 ATSMAASSID DAAVINELVV KLETCRQELP SGYKMNPIQF EKDDDTNYHM DLIAGLANMR 910 920 930 940 950 960 ARNYSIPEVD KLKAKFIAGR IIPAIATSTA MATGLVCLEL YKVLDGGHKV EDYRNTFANL 970 980 990 1000 1010 1020 ALPLFSMAEP VPPKVVKHQD MNWTVWDRWI LKDNPTLREL LQWLQNKGLN AYSISYGSCL 1030 1040 1050 1060 1070 1080 LYNSMFPKHK ERMDRKLVDL AREVAKADLP PYRKHFDVVV ACEDEEDNDV DIPQMSIYFR

References

[1]	"The tobacco ubiquitin-activating enzymes NtE1A and NtE1B are induced by tobacco mosaic virus, wounding and stress hormones." Takizawa M., Goto A., Watanabe Y. Mol. Cells 19:228-231(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AB124880 mRNA. Translation: BAD00984.1.
3D structure databases
HSSP	HSSP built from PDB template 1JW9 based on UniProtKB P12282.
ProteinModelPortal	Q75VJ8.
ModBase	Search...
Proteomic databases
ProMEX	Q75VJ8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
Gene3D	1.10.3240.10. 2 hits. 3.40.50.720. 4 hits.
InterPro	IPR009036. Molybdenum_cofac_synth_MoeB. IPR016040. NAD(P)-bd_dom. IPR000594. ThiF_NAD_FAD-bd. IPR018965. Ub-activating_enz_e1_C. IPR023280. Ub-like_act_enz_cat_cys_dom. IPR000127. UBact_repeat. IPR019572. Ubiquitin-activating_enzyme. IPR018075. UBQ-activ_enz_E1. IPR018074. UBQ-activ_enz_E1_AS. IPR000011. UBQ/SUMO-activ_enz_E1-like. [Graphical view]
Pfam	PF00899. ThiF. 2 hits. PF09358. UBA_e1_C. 1 hit. PF10585. UBA_e1_thiolCys. 1 hit. PF02134. UBACT. 2 hits. [Graphical view]
PRINTS	PR01849. UBIQUITINACT.
SMART	SM00985. UBA_e1_C. 1 hit. [Graphical view]
SUPFAM	SSF69572. MoeB. 2 hits.
TIGRFAMs	TIGR01408. Ube1. 1 hit.
PROSITE	PS00536. UBIQUITIN_ACTIVAT_1. 1 hit. PS00865. UBIQUITIN_ACTIVAT_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q75VJ8_TOBAC

Accession

Primary (citable) accession number: Q75VJ8

Entry history

Integrated into UniProtKB/TrEMBL:	July 5, 2004
Last sequence update:	July 5, 2004
Last modified:	May 1, 2013
This is version 54 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)