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Protein

Craniofacial development protein 1

Gene

Cfdp1

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

May play a role during embryogenesis.By similarity

GO - Biological processi

Keywordsi

Molecular functionDevelopmental protein

Names & Taxonomyi

Protein namesi
Recommended name:
Craniofacial development protein 1
Alternative name(s):
Bucentaur
Gene namesi
Name:Cfdp1
Synonyms:Bcnt
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 19

Organism-specific databases

RGDi735080. Cfdp1.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Centromere, Chromosome, Kinetochore

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002124971 – 295Craniofacial development protein 1Add BLAST295

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei80PhosphoserineCombined sources1
Modified residuei83PhosphoserineCombined sources1
Modified residuei84PhosphoserineCombined sources1
Modified residuei112PhosphoserineBy similarity1
Cross-linki146Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residuei212PhosphoserineBy similarity1
Modified residuei215N6-methyllysineBy similarity1
Modified residuei246PhosphoserineBy similarity1

Keywords - PTMi

Isopeptide bond, Methylation, Phosphoprotein, Ubl conjugation

Proteomic databases

PaxDbiQ75UQ2.
PRIDEiQ75UQ2.

PTM databases

iPTMnetiQ75UQ2.
PhosphoSitePlusiQ75UQ2.

Expressioni

Gene expression databases

BgeeiENSRNOG00000019326.
ExpressionAtlasiQ75UQ2. baseline.
GenevisibleiQ75UQ2. RN.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000026249.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini214 – 295BCNT-CPROSITE-ProRule annotationAdd BLAST82

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni174 – 213HydrophilicAdd BLAST40

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi2 – 108Glu-richAdd BLAST107

Phylogenomic databases

eggNOGiKOG4776. Eukaryota.
ENOG4111H9K. LUCA.
GeneTreeiENSGT00390000018141.
HOGENOMiHOG000247045.
HOVERGENiHBG081120.
InParanoidiQ75UQ2.
OMAiRTYNFAG.
OrthoDBiEOG091G0Z7H.
PhylomeDBiQ75UQ2.
TreeFamiTF313182.

Family and domain databases

InterProiView protein in InterPro
IPR011421. BCNT-C.
IPR027124. Swc5/CFDP.
PANTHERiPTHR23227. PTHR23227. 1 hit.
PfamiView protein in Pfam
PF07572. BCNT. 1 hit.
PROSITEiView protein in PROSITE
PS51279. BCNT_C. 1 hit.

Sequencei

Sequence statusi: Complete.

Q75UQ2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEEFDSEDFS TSDEDEDYVP SGGEYSEDDV NELVKEDEVD GEEQAEKTKG
60 70 80 90 100
KRRKAQSIPA RKRKQSGLLL DEEEDGEEDS GGSSREEDEE EQEGGLGSET
110 120 130 140 150
SRKKKEDELW ASFLNDVGTK SKAASSSQVK VAEETEETSS SKPLVKADEL
160 170 180 190 200
EKPKESEKVK ITKVFDFAGE EVRVTKEVDA TSKEAKSFLK QTEKEKPQAL
210 220 230 240 250
VTSAATPPPA GSGIKRTSGM SSLLGKIGAK KQKMSTLEKS KLDWESFKEE
260 270 280 290
EGIGEELAIH NRGKEGYIER KAFLERVDHR QFEIERDLRL SKMKP
Length:295
Mass (Da):32,969
Last modified:July 5, 2004 - v1
Checksum:i60F604F3BCED5885
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB125856 mRNA. Translation: BAD01499.1.
BC067246 mRNA. Translation: AAH67246.1.
RefSeqiNP_955410.1. NM_199378.3.
UniGeneiRn.128746.

Genome annotation databases

EnsembliENSRNOT00000026249; ENSRNOP00000026249; ENSRNOG00000019326.
GeneIDi292027.
KEGGirno:292027.
UCSCiRGD:735080. rat.

Similar proteinsi

Entry informationi

Entry nameiCFDP1_RAT
AccessioniPrimary (citable) accession number: Q75UQ2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 22, 2005
Last sequence update: July 5, 2004
Last modified: November 22, 2017
This is version 86 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome