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Protein

Probable D-serine dehydratase

Gene

dsdA

Organism
Geobacillus kaustophilus (strain HTA426)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-serine = pyruvate + NH3.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Lyase

Keywords - Ligandi

Pyridoxal phosphate

Names & Taxonomyi

Protein namesi
Recommended name:
Probable D-serine dehydrataseUniRule annotation (EC:4.3.1.18UniRule annotation)
Alternative name(s):
D-serine deaminaseUniRule annotation
Short name:
DSDUniRule annotation
Gene namesi
Name:dsdAUniRule annotation
Ordered Locus Names:GK1922
ORF Names:GKB09
OrganismiGeobacillus kaustophilus (strain HTA426)
Taxonomic identifieri235909 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeGeobacillus
Proteomesi
  • UP000001172 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002917311 – 441Probable D-serine dehydrataseAdd BLAST441

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei101N6-(pyridoxal phosphate)lysineUniRule annotation1

Interactioni

Protein-protein interaction databases

STRINGi235909.GK1922.

Structurei

3D structure databases

ProteinModelPortaliQ75TC9.
SMRiQ75TC9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the serine/threonine dehydratase family. DsdA subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105BZC. Bacteria.
COG3048. LUCA.
HOGENOMiHOG000218072.
KOiK01753.
OMAiESDPNCF.
OrthoDBiPOG091H0G2T.

Family and domain databases

HAMAPiMF_01030. D_Ser_dehydrat. 1 hit.
InterProiIPR011780. D_Ser_am_lyase.
IPR000634. Ser/Thr_deHydtase_PyrdxlP-BS.
IPR001926. TrpB-like_PLP-dep.
[Graphical view]
PANTHERiPTHR10314:SF9. PTHR10314:SF9. 2 hits.
PfamiPF00291. PALP. 1 hit.
[Graphical view]
SUPFAMiSSF53686. SSF53686. 1 hit.
TIGRFAMsiTIGR02035. D_Ser_am_lyase. 1 hit.
PROSITEiPS00165. DEHYDRATASE_SER_THR. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q75TC9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIMAAEEVFW RNPKYHAFAQ AIRTIPLRER DVKEAEERLR RFAPYIAKVF
60 70 80 90 100
PETQPAHGII ESPLVRIPNM QRRLEKMFQT NIEGDLLLKC DSHLPISGSI
110 120 130 140 150
KARGGIYEVL KHAEDLALAN GMIAIGEDYA VMASEEFRQF FSRYSLVVGS
160 170 180 190 200
TGNLGLSIGI IGAQLGFRVT VHMSADAKQW KKDLLRSKGV TVIEHLTDYN
210 220 230 240 250
KVVEEARRQS AEDPTSYFID DENSIHLFLG YAVAAFRLKK QLEDMNITVD
260 270 280 290 300
ETHPLFVYLP CGVGGGPGGV TFGLKLVYGD HVHCFFAEPT HSPCMLLGLM
310 320 330 340 350
TGEHDRVSVQ DFGLDNKTEA DGLAVGRPSR LVGNMLENVI SGVYTVDDST
360 370 380 390 400
LYRLLAAMVE TEEIYLEPSA LAGVAGPVRL FRDSAGQTYV EENDLKEKMK
410 420 430 440
NAVHICWATG GSMVPKGVME AYYREGMRIE TMTGNCFSEG R
Length:441
Mass (Da):49,082
Last modified:July 5, 2004 - v1
Checksum:i540C62A7F01ACEB9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB126619 Genomic DNA. Translation: BAD18349.1.
BA000043 Genomic DNA. Translation: BAD76207.1.
RefSeqiWP_011231408.1. NC_006510.1.

Genome annotation databases

EnsemblBacteriaiBAD76207; BAD76207; GK1922.
GeneIDi3185222.
KEGGigka:GK1922.
PATRICi21965211. VBIGeoKau81518_2061.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB126619 Genomic DNA. Translation: BAD18349.1.
BA000043 Genomic DNA. Translation: BAD76207.1.
RefSeqiWP_011231408.1. NC_006510.1.

3D structure databases

ProteinModelPortaliQ75TC9.
SMRiQ75TC9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi235909.GK1922.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAD76207; BAD76207; GK1922.
GeneIDi3185222.
KEGGigka:GK1922.
PATRICi21965211. VBIGeoKau81518_2061.

Phylogenomic databases

eggNOGiENOG4105BZC. Bacteria.
COG3048. LUCA.
HOGENOMiHOG000218072.
KOiK01753.
OMAiESDPNCF.
OrthoDBiPOG091H0G2T.

Family and domain databases

HAMAPiMF_01030. D_Ser_dehydrat. 1 hit.
InterProiIPR011780. D_Ser_am_lyase.
IPR000634. Ser/Thr_deHydtase_PyrdxlP-BS.
IPR001926. TrpB-like_PLP-dep.
[Graphical view]
PANTHERiPTHR10314:SF9. PTHR10314:SF9. 2 hits.
PfamiPF00291. PALP. 1 hit.
[Graphical view]
SUPFAMiSSF53686. SSF53686. 1 hit.
TIGRFAMsiTIGR02035. D_Ser_am_lyase. 1 hit.
PROSITEiPS00165. DEHYDRATASE_SER_THR. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiSDHD_GEOKA
AccessioniPrimary (citable) accession number: Q75TC9
Secondary accession number(s): Q5KYM9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 26, 2007
Last sequence update: July 5, 2004
Last modified: November 2, 2016
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.