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Q75T13

- PGAP1_HUMAN

UniProt

Q75T13 - PGAP1_HUMAN

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Protein

GPI inositol-deacylase

Gene

PGAP1

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli

Functioni

Involved in inositol deacylation of GPI-anchored proteins. GPI inositol deacylation may important for efficient transport of GPI-anchored proteins from the endoplasmic reticulum to the Golgi (By similarity).By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei174 – 1741By similarity

GO - Molecular functioni

  1. nuclease activity Source: UniProtKB
  2. phosphoric ester hydrolase activity Source: UniProtKB

GO - Biological processi

  1. anterior/posterior axis specification Source: Ensembl
  2. attachment of GPI anchor to protein Source: Reactome
  3. cellular protein metabolic process Source: Reactome
  4. C-terminal protein lipidation Source: Reactome
  5. embryonic pattern specification Source: Ensembl
  6. forebrain regionalization Source: Ensembl
  7. head development Source: Ensembl
  8. intracellular protein transport Source: InterPro
  9. myo-inositol transport Source: UniProtKB
  10. post-translational protein modification Source: Reactome
  11. sensory perception of sound Source: Ensembl
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Protein transport, Transport

Enzyme and pathway databases

ReactomeiREACT_1830. Attachment of GPI anchor to uPAR.

Names & Taxonomyi

Protein namesi
Recommended name:
GPI inositol-deacylase (EC:3.1.-.-)
Alternative name(s):
Post-GPI attachment to proteins factor 1
Short name:
hPGAP1
Gene namesi
Name:PGAP1
ORF Names:UNQ3024/PRO9822
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 2

Organism-specific databases

HGNCiHGNC:25712. PGAP1.

Subcellular locationi

GO - Cellular componenti

  1. endoplasmic reticulum Source: UniProtKB
  2. endoplasmic reticulum membrane Source: Reactome
  3. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Endoplasmic reticulum, Membrane

Pathology & Biotechi

Involvement in diseasei

Mental retardation, autosomal recessive 42 (MRT42) [MIM:615802]: A disorder characterized by significantly below average general intellectual functioning associated with impairments in adaptive behavior and manifested during the developmental period.1 Publication
Note: The disease is caused by mutations affecting the gene represented in this entry.
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti197 – 1971Missing in MRT42; results in loss of PI-specific phospholipase C sensitivity which could be rescued by expression of the wild-type protein. 1 Publication
VAR_071772

Keywords - Diseasei

Disease mutation, Mental retardation

Organism-specific databases

MIMi615802. phenotype.
Orphaneti401820. Autosomal recessive spastic paraplegia type 67.
PharmGKBiPA162399235.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 922922GPI inositol-deacylasePRO_0000277623Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi402 – 4021N-linked (GlcNAc...)Sequence Analysis
Glycosylationi558 – 5581N-linked (GlcNAc...)Sequence Analysis

Keywords - PTMi

Glycoprotein

Proteomic databases

MaxQBiQ75T13.
PaxDbiQ75T13.
PRIDEiQ75T13.

PTM databases

PhosphoSiteiQ75T13.

Expressioni

Gene expression databases

BgeeiQ75T13.
CleanExiHS_PGAP1.
ExpressionAtlasiQ75T13. baseline and differential.
GenevestigatoriQ75T13.

Interactioni

Protein-protein interaction databases

BioGridi123093. 13 interactions.
IntActiQ75T13. 2 interactions.
MINTiMINT-4828389.
STRINGi9606.ENSP00000346809.

Structurei

3D structure databases

ProteinModelPortaliQ75T13.
ModBaseiSearch...
MobiDBiSearch...

Topological domain

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 1111CytoplasmicSequence AnalysisAdd
BLAST
Topological domaini33 – 641609LumenalSequence AnalysisAdd
BLAST
Topological domaini663 – 6686CytoplasmicSequence Analysis
Topological domaini690 – 73344LumenalSequence AnalysisAdd
BLAST
Topological domaini755 – 81763CytoplasmicSequence AnalysisAdd
BLAST
Topological domaini839 – 85315LumenalSequence AnalysisAdd
BLAST
Topological domaini875 – 89319CytoplasmicSequence AnalysisAdd
BLAST
Topological domaini915 – 9228LumenalSequence Analysis

Transmembrane

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei12 – 3221HelicalSequence AnalysisAdd
BLAST
Transmembranei642 – 66221HelicalSequence AnalysisAdd
BLAST
Transmembranei669 – 68921HelicalSequence AnalysisAdd
BLAST
Transmembranei734 – 75421HelicalSequence AnalysisAdd
BLAST
Transmembranei818 – 83821HelicalSequence AnalysisAdd
BLAST
Transmembranei854 – 87421HelicalSequence AnalysisAdd
BLAST
Transmembranei894 – 91421HelicalSequence AnalysisAdd
BLAST

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI inositol-deacylase family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG312611.
GeneTreeiENSGT00390000016484.
HOVERGENiHBG082122.
InParanoidiQ75T13.
KOiK05294.
OMAiTKFVHEC.
OrthoDBiEOG7KM5RZ.
PhylomeDBiQ75T13.
TreeFamiTF314565.

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
InterProiIPR029058. AB_hydrolase.
IPR012908. PGAP1-like.
[Graphical view]
PfamiPF07819. PGAP1. 1 hit.
[Graphical view]
SUPFAMiSSF53474. SSF53474. 1 hit.
PROSITEiPS00120. LIPASE_SER. 1 hit.
[Graphical view]

Sequences (4)i

Sequence statusi: Complete.

This entry describes 4 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: Q75T13) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MFLHSVNLWN LAFYVFMVFL ATLGLWDVFF GFEENKCSMS YMFEYPEYQK
60 70 80 90 100
IELPKKLAKR YPAYELYLYG EGSYAEEHKI LPLTGIPVLF LPGNAGSYKQ
110 120 130 140 150
VRSIGSIALR KAEDIDFKYH FDFFSVNFNE ELVALYGGSL QKQTKFVHEC
160 170 180 190 200
IKTILKLYKG QEFAPKSVAI IGHSMGGLVA RALLTLKNFK HDLINLLITQ
210 220 230 240 250
ATPHVAPVMP LDRFITDFYT TVNNYWILNA RHINLTTLSV AGGFRDYQVR
260 270 280 290 300
SGLTFLPKLS HHTSALSVVS SAVPKTWVST DHLSIVWCKQ LQLTTVRAFF
310 320 330 340 350
DLIDADTKQI TQNSKKKLSV LYHHFIRHPS KHFEENPAII SDLTGTSMWV
360 370 380 390 400
LVKVSKWTYV AYNESEKIYF TFPLENHRKI YTHVYCQSTM LDTNSWIFAC
410 420 430 440 450
INSTSMCLQG VDLSWKAELL PTIKYLTLRL QDYPSLSHLV VYVPSVRGSK
460 470 480 490 500
FVVDCEFFKK EKRYIQLPVT HLFSFGLSSR KVVLNTNGLY YNLELLNFGQ
510 520 530 540 550
IYQAFKINVV SKCSAVKEEI TSIYRLHIPW SYEDSLTIAQ APSSTEISLK
560 570 580 590 600
LHIAQPENNT HVALFKMYTS SDCRYEVTVK TSFSQILGQV VRFHGGALPA
610 620 630 640 650
YVVSNILLAY RGQLYSLFST GCCLEYATML DKEAKPYKVD PFVIIIKFLL
660 670 680 690 700
GYKWFKELWD VLLLPELDAV ILTCQSMCFP LISLILFLFG TCTAYWSGLL
710 720 730 740 750
SSASVRLLSS LWLALKRPSE LPKDIKMISP DLPFLTIVLI IVSWTTCGAL
760 770 780 790 800
AILLSYLYYV FKVVHLQASL TTFKNSQPVN PKHSRRSEKK SNHHKDSSIH
810 820 830 840 850
HLRLSANDAE DSLRMHSTVI NLLTWIVLLS MPSLIYWLKN LRYYFKLNPD
860 870 880 890 900
PCKPLAFILI PTMAILGNTY TVSIKSSKLL KTTSQFPLPL AVGVIAFGSA
910 920
HLYRLPCFVF IPLLLHALCN FM
Length:922
Mass (Da):105,383
Last modified:July 5, 2004 - v1
Checksum:i0305D18F5BF292D6
GO
Isoform 2 (identifier: Q75T13-2) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-174: Missing.

Note: No experimental confirmation available.

Show »
Length:748
Mass (Da):85,239
Checksum:i5C67D37891F3FAAC
GO
Isoform 3 (identifier: Q75T13-3) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     592-592: R → A
     593-922: Missing.

Note: No experimental confirmation available.

Show »
Length:592
Mass (Da):67,974
Checksum:iBD6B7BB40B8A0BC1
GO
Isoform 4 (identifier: Q75T13-4) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     50-269: Missing.
     652-922: Missing.

Note: May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. No experimental confirmation available.

Show »
Length:431
Mass (Da):49,845
Checksum:i86F82D676245A7E3
GO

Sequence cautioni

The sequence BC040517 differs from that shown. Reason: Frameshift at position 333.
The sequence AAQ88987.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti304 – 3041D → G in BAB14035. (PubMed:14702039)Curated
Sequence conflicti389 – 3891T → A in CAH10543. (PubMed:17974005)Curated
Sequence conflicti701 – 7011S → P in CAH10543. (PubMed:17974005)Curated
Sequence conflicti809 – 8091A → T in CAH10543. (PubMed:17974005)Curated

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti197 – 1971Missing in MRT42; results in loss of PI-specific phospholipase C sensitivity which could be rescued by expression of the wild-type protein. 1 Publication
VAR_071772

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1 – 174174Missing in isoform 2. 1 PublicationVSP_023040Add
BLAST
Alternative sequencei50 – 269220Missing in isoform 4. 1 PublicationVSP_023041Add
BLAST
Alternative sequencei592 – 5921R → A in isoform 3. 1 PublicationVSP_023042
Alternative sequencei593 – 922330Missing in isoform 3. 1 PublicationVSP_023043Add
BLAST
Alternative sequencei652 – 922271Missing in isoform 4. 1 PublicationVSP_023044Add
BLAST

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB128038 mRNA. Translation: BAD13427.1.
AK022439 mRNA. Translation: BAB14035.1.
BX648642 mRNA. Translation: CAH10543.1.
AC017035 Genomic DNA. Translation: AAY15059.1.
AC012486 Genomic DNA. Translation: AAX88854.1.
BC040517 mRNA. No translation available.
AY358624 mRNA. Translation: AAQ88987.1. Different initiation.
CCDSiCCDS2318.1. [Q75T13-1]
RefSeqiNP_079265.2. NM_024989.3. [Q75T13-1]
XP_005246923.1. XM_005246866.1. [Q75T13-2]
UniGeneiHs.229988.

Genome annotation databases

EnsembliENST00000354764; ENSP00000346809; ENSG00000197121. [Q75T13-1]
ENST00000409475; ENSP00000387028; ENSG00000197121. [Q75T13-3]
GeneIDi80055.
KEGGihsa:80055.
UCSCiuc002utw.3. human. [Q75T13-1]
uc002uty.1. human. [Q75T13-3]

Polymorphism databases

DMDMi74758940.

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB128038 mRNA. Translation: BAD13427.1 .
AK022439 mRNA. Translation: BAB14035.1 .
BX648642 mRNA. Translation: CAH10543.1 .
AC017035 Genomic DNA. Translation: AAY15059.1 .
AC012486 Genomic DNA. Translation: AAX88854.1 .
BC040517 mRNA. No translation available.
AY358624 mRNA. Translation: AAQ88987.1 . Different initiation.
CCDSi CCDS2318.1. [Q75T13-1 ]
RefSeqi NP_079265.2. NM_024989.3. [Q75T13-1 ]
XP_005246923.1. XM_005246866.1. [Q75T13-2 ]
UniGenei Hs.229988.

3D structure databases

ProteinModelPortali Q75T13.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 123093. 13 interactions.
IntActi Q75T13. 2 interactions.
MINTi MINT-4828389.
STRINGi 9606.ENSP00000346809.

PTM databases

PhosphoSitei Q75T13.

Polymorphism databases

DMDMi 74758940.

Proteomic databases

MaxQBi Q75T13.
PaxDbi Q75T13.
PRIDEi Q75T13.

Protocols and materials databases

DNASUi 80055.
Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000354764 ; ENSP00000346809 ; ENSG00000197121 . [Q75T13-1 ]
ENST00000409475 ; ENSP00000387028 ; ENSG00000197121 . [Q75T13-3 ]
GeneIDi 80055.
KEGGi hsa:80055.
UCSCi uc002utw.3. human. [Q75T13-1 ]
uc002uty.1. human. [Q75T13-3 ]

Organism-specific databases

CTDi 80055.
GeneCardsi GC02M197697.
HGNCi HGNC:25712. PGAP1.
MIMi 611655. gene.
615802. phenotype.
neXtProti NX_Q75T13.
Orphaneti 401820. Autosomal recessive spastic paraplegia type 67.
PharmGKBi PA162399235.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG312611.
GeneTreei ENSGT00390000016484.
HOVERGENi HBG082122.
InParanoidi Q75T13.
KOi K05294.
OMAi TKFVHEC.
OrthoDBi EOG7KM5RZ.
PhylomeDBi Q75T13.
TreeFami TF314565.

Enzyme and pathway databases

Reactomei REACT_1830. Attachment of GPI anchor to uPAR.

Miscellaneous databases

GenomeRNAii 80055.
NextBioi 70254.
PROi Q75T13.
SOURCEi Search...

Gene expression databases

Bgeei Q75T13.
CleanExi HS_PGAP1.
ExpressionAtlasi Q75T13. baseline and differential.
Genevestigatori Q75T13.

Family and domain databases

Gene3Di 3.40.50.1820. 1 hit.
InterProi IPR029058. AB_hydrolase.
IPR012908. PGAP1-like.
[Graphical view ]
Pfami PF07819. PGAP1. 1 hit.
[Graphical view ]
SUPFAMi SSF53474. SSF53474. 1 hit.
PROSITEi PS00120. LIPASE_SER. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Inositol deacylation of glycosylphosphatidylinositol-anchored proteins is mediated by mammalian PGAP1 and yeast Bst1p."
    Tanaka S., Maeda Y., Tashima Y., Kinoshita T.
    J. Biol. Chem. 279:14256-14263(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3).
    Tissue: Mammary gland.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
    Tissue: Fetal kidney.
  4. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
    Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H.
    , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K.
    Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 4).
    Tissue: Testis.
  6. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 705-922 (ISOFORMS 1/2).
  7. "Null mutation in PGAP1 impairing Gpi-anchor maturation in patients with intellectual disability and encephalopathy."
    Murakami Y., Tawamie H., Maeda Y., Buettner C., Buchert R., Radwan F., Schaffer S., Sticht H., Aigner M., Reis A., Kinoshita T., Jamra R.A.
    PLoS Genet. 10:E1004320-E1004320(2014) [PubMed] [Europe PMC] [Abstract]
    Cited for: VARIANT MRT42 LEU-197 DEL, CHARACTERIZATION OF VARIANT MRT42 LEU-197 DEL.

Entry informationi

Entry nameiPGAP1_HUMAN
AccessioniPrimary (citable) accession number: Q75T13
Secondary accession number(s): Q4G0R8
, Q4ZG47, Q53SM0, Q6AW92, Q6UWV4, Q9HA24
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 6, 2007
Last sequence update: July 5, 2004
Last modified: October 29, 2014
This is version 95 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 2
    Human chromosome 2: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  4. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3