Unreviewed, UniProtKB/TrEMBL Q75RY1 (Q75RY1_HUMAN)

Names and origin

Protein names

Submitted name:
    Growth differentiation factor 7 EMBL BAD07014.1

Gene names

Name:

gdf7 EMBL BAD07014.1

Organism

Homo sapiens (Human) EMBL BAD07014.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	453 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Sequence similarities

Belongs to the TGF-beta family. RuleBase RU000354V2

Ontologies

Keywords
Cellular component	Secreted Spearmint SPM001111
Molecular function	Growth factor RuleBase RU000354V2 Spearmint SPM001111
Gene Ontology (GO)
Biological process	growth Inferred from electronic annotation. Source: InterPro
Cellular component	extracellular region Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	growth factor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q75RY1-1 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: 9FD8CB759C63DF1D	FASTA	453	47,121
	10 20 30 40 50 60 MDLSAAAALC LWLLSACRPR DGLEAAAVLR AAGAGPVRSP GGGGGGGGGG GGGRTLAQAA 70 80 90 100 110 120 GAAAVPAAAV PRARAARRAA GSGFRNGSVV PHHFMMSLYR SLAGRAPAGA AAVSASGHGR 130 140 150 160 170 180 ADTITGFTDQ ATQDESAAET GQSFLFDVSS LNDADEVVGA ELRVLRRGSP ESGPGSWTSP 190 200 210 220 230 240 PLLLLSTCPG AARAPRLLYS RAAEPLVGQR WEAFDVADAM RRHRREPRPP RAFCLLLRAV 250 260 270 280 290 300 AGPVPSPLAL RRLGFGWPGG GGSAAEERAV LVVSSRTQRK ESLFREIRAQ ARALGAALAS 310 320 330 340 350 360 EPLPDPGTGT ASPRAVIGGR RRRRTALAGT RTAQGSGGGA GRGHGRRGRS RCSRKPLHVD 370 380 390 400 410 420 FKELGWDDWI IAPLDYEAYH CEGLCDFPLR SHLEPTNHAI IQTLLNSMAP DAAPASCCVP 430 440 450 ARLSPISILY IDAANNVVYK QYEDMVVEAC GCR

References

[1]	"Homo sapiens growth differentiation factor 7 (GDF7) mRNA, complete cds." Suzuki M., Shimokawa H., Kasugai S. Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AB158468 mRNA. Translation: BAD07014.1.
UniGene	Hs.447688
3D structure databases
HSSP	HSSP built from PDB template 1KLA based on UniProtKB P01137.
SMR	Q75RY1. Positions 349-453.
ModBase	Search...
Genome annotation databases
Ensembl	ENSG00000143869. Homo sapiens. [Contig view]
Organism-specific databases
HGNC	HGNC:4222. GDF7.
GenAtlas	Search...
GeneCards	Search...
Phylogenomic databases
HOGENOM	Q75RY1.
HOVERGEN	Q75RY1.
Gene expression databases
ArrayExpress	Q75RY1.
Family and domain databases
InterPro	IPR001839. TGFb. IPR017948. TGFb_CS. IPR001111. TGFb_N. IPR015615. TGFbeta. [Graphical view]
PANTHER	PTHR11848. TGFbeta. 1 hit.
Pfam	PF00019. TGF_beta. 1 hit. PF00688. TGFb_propeptide. 1 hit. [Graphical view]
ProDom	PD000357. TGFb. 1 hit. [Graphical view] [Entries sharing at least one domain]
SMART	SM00204. TGFB. 1 hit. [Graphical view]
PROSITE	PS00250. TGF_BETA_1. 1 hit. PS51362. TGF_BETA_2. 1 hit. [Graphical view]

Entry information

Entry name

Q75RY1_HUMAN

Accession

Primary (citable) accession number: Q75RY1

Entry history

Integrated into UniProtKB/TrEMBL:	July 5, 2004
Last sequence update:	July 5, 2004
Last modified:	November 25, 2008
This is version 28 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)