Q75RY1 (Q75RY1_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Growth differentiation factor 7 EMBL BAD07014.1

Gene names

Name:

gdf7 EMBL BAD07014.1

Organism

Homo sapiens (Human) EMBL BAD07014.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	453 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the TGF-beta family. RuleBase RU000354

Ontologies

Keywords
Cellular component	Secreted SAAS SAAS015615
Molecular function	Growth factor RuleBase RU000354 SAAS SAAS015615
PTM	Disulfide bond SAAS SAAS015615
Gene Ontology (GO)
Biological process	growth Inferred from electronic annotation. Source: InterPro
Molecular function	growth factor activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q75RY1 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: 9FD8CB759C63DF1D	FASTA	453	47,121
	10 20 30 40 50 60 MDLSAAAALC LWLLSACRPR DGLEAAAVLR AAGAGPVRSP GGGGGGGGGG GGGRTLAQAA 70 80 90 100 110 120 GAAAVPAAAV PRARAARRAA GSGFRNGSVV PHHFMMSLYR SLAGRAPAGA AAVSASGHGR 130 140 150 160 170 180 ADTITGFTDQ ATQDESAAET GQSFLFDVSS LNDADEVVGA ELRVLRRGSP ESGPGSWTSP 190 200 210 220 230 240 PLLLLSTCPG AARAPRLLYS RAAEPLVGQR WEAFDVADAM RRHRREPRPP RAFCLLLRAV 250 260 270 280 290 300 AGPVPSPLAL RRLGFGWPGG GGSAAEERAV LVVSSRTQRK ESLFREIRAQ ARALGAALAS 310 320 330 340 350 360 EPLPDPGTGT ASPRAVIGGR RRRRTALAGT RTAQGSGGGA GRGHGRRGRS RCSRKPLHVD 370 380 390 400 410 420 FKELGWDDWI IAPLDYEAYH CEGLCDFPLR SHLEPTNHAI IQTLLNSMAP DAAPASCCVP 430 440 450 ARLSPISILY IDAANNVVYK QYEDMVVEAC GCR

References

[1]	"Homo sapiens growth differentiation factor 7 (GDF7) mRNA, complete cds." Suzuki M., Shimokawa H., Kasugai S. Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AB158468 mRNA. Translation: BAD07014.1.
IPI	IPI00337348.
RefSeq	NP_878248.2. NM_182828.2.
UniGene	Hs.447688.
3D structure databases
HSSP	HSSP built from PDB template 1KLA based on UniProtKB P01137.
ProteinModelPortal	Q75RY1.
SMR	Q75RY1. Positions 349-453.
ModBase	Search...
Protein-protein interaction databases
STRING	Q75RY1.
Proteomic databases
PRIDE	Q75RY1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	151449.
KEGG	hsa:151449.
Organism-specific databases
CTD	151449.
PharmGKB	PA28637.
Phylogenomic databases
eggNOG	prNOG04294.
HOGENOM	HBG717159.
HOVERGEN	HBG107938.
Gene expression databases
Bgee	Q75RY1.
Family and domain databases
InterPro	IPR001839. TGF-b_C. IPR001111. TGF-b_N. IPR015615. TGF-beta-rel. IPR017948. TGFb_CS. [Graphical view]
KO	K04664.
PANTHER	PTHR11848. TGFbeta. 1 hit.
Pfam	PF00019. TGF_beta. 1 hit. PF00688. TGFb_propeptide. 1 hit. [Graphical view]
SMART	SM00204. TGFB. 1 hit. [Graphical view]
PROSITE	PS00250. TGF_BETA_1. 1 hit. PS51362. TGF_BETA_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q75RY1_HUMAN

Accession

Primary (citable) accession number: Q75RY1

Entry history

Integrated into UniProtKB/TrEMBL:	July 5, 2004
Last sequence update:	July 5, 2004
Last modified:	January 25, 2012
This is version 50 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.