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Protein
Submitted name:

STX1A protein

Gene

STX1A

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
STX1A proteinImported
Submitted name:
Syntaxin 1A (Brain), isoform CRA_eImported
Submitted name:
Syntaxin 1A isoform AImported
Submitted name:
Uncharacterized protein STX1AImported
Submitted name:
cDNA, FLJ94630, Homo sapiens syntaxin 1A (brain) (STX1A), mRNAImported
Gene namesi
Name:STX1AImported
ORF Names:hCG_96107Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei266 – 287HelicalSequence analysisAdd BLAST22

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA36233.

Expressioni

Gene expression databases

BgeeiENSG00000106089.

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini192 – 254T-SNARE coiled-coil homologyInterPro annotationAdd BLAST63

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili68 – 106Sequence analysisAdd BLAST39

Sequence similaritiesi

Belongs to the syntaxin family.UniRule annotationSAAS annotation

Keywords - Domaini

Coiled coilPROSITE-ProRule annotationSAAS annotation, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG0810. Eukaryota.
COG5074. LUCA.
HOVERGENiHBG000497.
KOiK04560.
OMAiAELHQMF.
OrthoDBiEOG091G0EUK.

Family and domain databases

InterProiView protein in InterPro
IPR010989. SNARE.
IPR028669. STX1A/1B.
IPR006012. Syntaxin/epimorphin_CS.
IPR006011. Syntaxin_N.
IPR000727. T_SNARE_dom.
PANTHERiPTHR19957:SF187. PTHR19957:SF187. 1 hit.
PfamiView protein in Pfam
PF05739. SNARE. 1 hit.
PF00804. Syntaxin. 1 hit.
SMARTiView protein in SMART
SM00503. SynN. 1 hit.
SM00397. t_SNARE. 1 hit.
SUPFAMiSSF47661. SSF47661. 1 hit.
PROSITEiView protein in PROSITE
PS00914. SYNTAXIN. 1 hit.
PS50192. T_SNARE. 1 hit.

Sequencei

Sequence statusi: Complete.

Q75ME0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKDRTQELRT AKDSDDDDDV AVTVDRDRFM DEFFEQVEEI RGFIDKIAEN
60 70 80 90 100
VEEVKRKHSA ILASPNPDEK TKEELEELMS DIKKTANKVR SKLKSIEQSI
110 120 130 140 150
EQEEGLNRSS ADLRIRKTQH STLSRKFVEV MSEYNATQSD YRERCKGRIQ
160 170 180 190 200
RQLEITGRTT TSEELEDMLE SGNPAIFASG IIMDSSISKQ ALSEIETRHS
210 220 230 240 250
EIIKLENSIR ELHDMFMDMA MLVESQGEMI DRIEYNVEHA VDYVERAVSD
260 270 280
TKKAVKYQSK ARRKKIMIII CCVILGIVIA STVGGIFA
Length:288
Mass (Da):33,023
Last modified:May 10, 2005 - v1
Checksum:i8AC787EFCE65ACA1
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei288Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC073846 Genomic DNA. Translation: AAS07469.1.
KJ534952 mRNA. Translation: AHW56592.1.
AK313980 mRNA. Translation: BAG36694.1.
CR457018 mRNA. Translation: CAG33299.1.
CH471200 Genomic DNA. Translation: EAW69653.1.
CH471200 Genomic DNA. Translation: EAW69654.1.
RefSeqiNP_004594.1. NM_004603.3.
UniGeneiHs.647024.

Genome annotation databases

GeneIDi6804.
KEGGihsa:6804.
UCSCiuc003tyx.4. human.

Similar proteinsi

Entry informationi

Entry nameiQ75ME0_HUMAN
AccessioniPrimary (citable) accession number: Q75ME0
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: August 30, 2017
This is version 115 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.