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Q75KK8 (MPK14_ORYSJ) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 69. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Mitogen-activated protein kinase 14

Short name=MAP kinase 14
EC=2.7.11.24
Gene names
Name:MPK14
Ordered Locus Names:Os05g0143500, LOC_Os05g05160
ORF Names:OJ1264_A04.20, OJ1607_F09.3
OrganismOryza sativa subsp. japonica (Rice) [Reference proteome]
Taxonomic identifier39947 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza

Protein attributes

Sequence length542 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

ATP + a protein = ADP + a phosphoprotein.

Enzyme regulation

Activated by threonine and tyrosine phosphorylation By similarity.

Domain

The TXY motif contains the threonine and tyrosine residues whose phosphorylation activates the MAP kinases.

Post-translational modification

Dually phosphorylated on Thr-175 and Tyr-177, which activates the enzyme By similarity.

Sequence similarities

Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.

Contains 1 protein kinase domain.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 542542Mitogen-activated protein kinase 14
PRO_0000239757

Regions

Domain13 – 304292Protein kinase
Nucleotide binding19 – 279ATP By similarity
Motif175 – 1773TXY

Sites

Active site1391Proton acceptor By similarity
Binding site421ATP By similarity

Amino acid modifications

Modified residue1751Phosphothreonine By similarity
Modified residue1771Phosphotyrosine By similarity

Sequences

Sequence LengthMass (Da)Tools
Q75KK8 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: 1E797CEF2BD8631A

FASTA54261,762
        10         20         30         40         50         60 
MDFFTEYGEG NRYKIEEVIG KGSYGVVCSA LDTHTGDKVA IKKINDIFEH VSDATRILRE 

        70         80         90        100        110        120 
IKLLRLLRHP DIVEIKHILL PPSRREFKDI YVVFELMESD LHQVIKANDD LTPEHYQFFL 

       130        140        150        160        170        180 
YQLLRGLKYI HTANVFHRDL KPKNILANAD CKLKICDFGL ARVAFSDTPT AIFWTDYIAT 

       190        200        210        220        230        240 
RWYRAPELCG SFFSKYTPAI DIWSIGCIFA ELLTGKPLFP GKNVVHQLDI ITDLLGTPSP 

       250        260        270        280        290        300 
ETISRIRNEK ARRYLNSMRR KKPIPFTQKF PNADPLAMRL LERMLAFDPK DRPSAEEALA 

       310        320        330        340        350        360 
DPYFKNIANV DREPSAQPIT KLEFEFERRR ITKEDIRELI YREILEYHPK MLREFLEGTE 

       370        380        390        400        410        420 
STGFMYPSAV DHFKKQFAYL EEHYAKGSTA APPERQHNSL PRPCVVYSDN RPQSTASVTE 

       430        440        450        460        470        480 
DLSRCLIRDN NLKSQDSASV GASRIPQGAA ARPGKAVGSV LRYGNCSTSA AEQQYEQRRV 

       490        500        510        520        530        540 
VRNPAIAPNS SVPLGSSYPR RNQTCKSETG DVERIDSSQT GPPKPYVANK LPATVDGRSG 


HW 

« Hide

References

« Hide 'large scale' references
[1]"A fine physical map of the rice chromosome 5."
Cheng C.-H., Chung M.C., Liu S.-M., Chen S.-K., Kao F.Y., Lin S.-J., Hsiao S.-H., Tseng I.C., Hsing Y.-I.C., Wu H.-P., Chen C.-S., Shaw J.-F., Wu J., Matsumoto T., Sasaki T., Chen H.-C., Chow T.-Y.
Mol. Genet. Genomics 274:337-345(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Nipponbare.
[2]"Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice."
The rice full-length cDNA consortium
Science 301:376-379(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Nipponbare.
[3]"Molecular analysis of the rice MAP kinase gene family in relation to Magnaporthe grisea infection."
Reyna N.S., Yang Y.
Mol. Plant Microbe Interact. 19:530-540(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NOMENCLATURE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AC104277 Genomic DNA. Translation: AAS98446.1.
AC104283 Genomic DNA. Translation: AAU90196.1.
AK063944 mRNA. No translation available.

3D structure databases

ProteinModelPortalQ75KK8.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING39947.LOC_Os05g05160.1.

Proteomic databases

PRIDEQ75KK8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsOS05T0143500-02; OS05T0143500-02; OS05G0143500.

Organism-specific databases

GrameneQ75KK8.

Phylogenomic databases

eggNOGCOG0515.
OMAESARYEL.

Family and domain databases

InterProIPR011009. Kinase-like_dom.
IPR003527. MAP_kinase_CS.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR002290. Ser/Thr_dual-sp_kinase_dom.
[Graphical view]
PfamPF00069. Pkinase. 1 hit.
[Graphical view]
SMARTSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMSSF56112. SSF56112. 1 hit.
PROSITEPS01351. MAPK. 1 hit.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameMPK14_ORYSJ
AccessionPrimary (citable) accession number: Q75KK8
Entry history
Integrated into UniProtKB/Swiss-Prot: June 13, 2006
Last sequence update: July 5, 2004
Last modified: May 14, 2014
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Oryza sativa (rice)

Index of Oryza sativa entries and their corresponding gene designations