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Q75G34 (COX3_ASHGO) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 71. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Cytochrome c oxidase subunit 3

EC=1.9.3.1
Alternative name(s):
Cytochrome c oxidase polypeptide III
Gene names
Name:COX3
Ordered Locus Names:AMI003W
ORF Names:AgCOX3
Encoded onMitochondrion
OrganismAshbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii) [Reference proteome]
Taxonomic identifier284811 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeEremothecium

Protein attributes

Sequence length269 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Subunits I, II and III form the functional core of the enzyme complex.

Catalytic activity

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

Subunit structure

Composed of at least 11 subunits.

Subcellular location

Mitochondrion inner membrane; Multi-pass membrane protein By similarity.

Sequence similarities

Belongs to the cytochrome c oxidase subunit 3 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 269269Cytochrome c oxidase subunit 3
PRO_0000183742

Regions

Transmembrane21 – 4121Helical; Potential
Transmembrane44 – 6421Helical; Potential
Transmembrane90 – 11021Helical; Potential
Transmembrane138 – 16023Helical; Potential
Transmembrane167 – 18721Helical; Potential
Transmembrane205 – 22521Helical; Potential
Transmembrane248 – 26821Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q75G34 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: 593DCBA0BBBE7CA8

FASTA26930,622
        10         20         30         40         50         60 
MLYLNRSKFQ QFPFHLVTPS PWPIVTSFSL LGLTLTLAFT MHGIIGNIYP LLLSLLVVLL 

        70         80         90        100        110        120 
TMTLWFRDIV AETTYLGDHT LAVRKGINLG FTLFVVSEVL IFASLFWAYF HSAMSPDITL 

       130        140        150        160        170        180 
GNVWPPVGIE AVQPTELPLL NTIILLASGT TITYSHHGLI EGNRKHALSG LTITFWLIVT 

       190        200        210        220        230        240 
FVLCQYIEYS NTSFTITDGI YGSVFFAGTG LHFLHMVMLT IMLGINYWRM RNYHLTSTHH 

       250        260 
VGYETTTIYL HVLDIIWLAL YICFYWWGV 

« Hide

References

« Hide 'large scale' references
[1]"The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces cerevisiae genome."
Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S., Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A., Gaffney T.D., Philippsen P.
Science 304:304-307(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056.
[2]"Genomes of Ashbya fungi isolated from insects reveal four mating-type loci, numerous translocations, lack of transposons, and distinct gene duplications."
Dietrich F.S., Voegeli S., Kuo S., Philippsen P.
G3 (Bethesda) 3:1225-1239(2013) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE016821 Genomic DNA. Translation: AAS50170.1.
RefSeqNP_987080.1. NC_005789.1.

3D structure databases

ProteinModelPortalQ75G34.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING33169.AGOS_AMI003W.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiAAS50170; AAS50170; AGOS_AMI003W.
GeneID2760768.
KEGGago:AGOS_AMI003W.

Phylogenomic databases

eggNOGCOG1845.
HOGENOMHOG000264954.
KOK02262.
OrthoDBEOG7V76HP.

Family and domain databases

Gene3D1.20.120.80. 1 hit.
InterProIPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR000298. Cyt_c_oxidase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
[Graphical view]
PANTHERPTHR11403. PTHR11403. 1 hit.
PfamPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMSSF81452. SSF81452. 1 hit.
PROSITEPS50253. COX3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCOX3_ASHGO
AccessionPrimary (citable) accession number: Q75G34
Entry history
Integrated into UniProtKB/Swiss-Prot: July 19, 2004
Last sequence update: July 5, 2004
Last modified: July 9, 2014
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families