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Q75DY2 (RIFK_ASHGO) Reviewed, UniProtKB/Swiss-Prot

Last modified January 22, 2014. Version 71. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Riboflavin kinase

EC=2.7.1.26
Alternative name(s):
Flavin mononucleotide kinase 1
Gene names
Name:FMN1
Ordered Locus Names:ABL109W
OrganismAshbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii) [Reference proteome]
Taxonomic identifier284811 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeEremothecium

Protein attributes

Sequence length186 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) coenzyme By similarity.

Catalytic activity

ATP + riboflavin = ADP + FMN.

Cofactor

Zinc or magnesium By similarity.

Pathway

Cofactor biosynthesis; FMN biosynthesis; FMN from riboflavin (ATP route): step 1/1.

Sequence similarities

Belongs to the flavokinase family.

Sequence caution

The sequence AAS50662.1 differs from that shown. Reason: Erroneous initiation.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 186186Riboflavin kinase
PRO_0000301832

Sites

Active site1231Nucleophile By similarity
Metal binding421Magnesium or zinc By similarity

Sequences

Sequence LengthMass (Da)Tools
Q75DY2 [UniParc].

Last modified September 11, 2007. Version 2.
Checksum: DA16FB2E83EF3A9E

FASTA18620,984
        10         20         30         40         50         60 
MARRPVDIPI PASPVQPFPI LTEYVDIVAG FGRGSAELGI PTANVPIEQL PSEVNEMATG 

        70         80         90        100        110        120 
VYFGWARLRP NMDQEAQVHH RNDGSEVIYN FGSKLSETER GVFPIVLSVG WNPFYNNSKK 

       130        140        150        160        170        180 
TVELHILNDF EEDFYGAKIK FSFLGYIRPE LNYTTKEALI EDIHTDIKIA SEVLHTEPYS 


SLKNQL 

« Hide

References

« Hide 'large scale' references
[1]"The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces cerevisiae genome."
Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S., Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A., Gaffney T.D., Philippsen P.
Science 304:304-307(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056.
[2]"Genomes of Ashbya fungi isolated from insects reveal four mating-type loci, numerous translocations, lack of transposons, and distinct gene duplications."
Dietrich F.S., Voegeli S., Kuo S., Philippsen P.
G3 (Bethesda) 3:1225-1239(2013) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE016815 Genomic DNA. Translation: AAS50662.1. Different initiation.
RefSeqNP_982838.1. NM_208191.1.

3D structure databases

ProteinModelPortalQ75DY2.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING33169.AGOS_ABL109W.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4618918.
KEGGago:AGOS_ABL109W.

Phylogenomic databases

eggNOGCOG0196.
HOGENOMHOG000260803.
KOK00861.
OrthoDBEOG7K3V05.

Enzyme and pathway databases

UniPathwayUPA00276; UER00406.

Family and domain databases

Gene3D2.40.30.30. 1 hit.
InterProIPR023468. Riboflavin_kinase.
IPR015865. Riboflavin_kinase_bac/euk.
IPR023465. Riboflavin_kinase_domain.
[Graphical view]
PANTHERPTHR22749. PTHR22749. 1 hit.
PfamPF01687. Flavokinase. 1 hit.
[Graphical view]
SMARTSM00904. Flavokinase. 1 hit.
[Graphical view]
SUPFAMSSF82114. SSF82114. 2 hits.
ProtoNetSearch...

Entry information

Entry nameRIFK_ASHGO
AccessionPrimary (citable) accession number: Q75DY2
Entry history
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: September 11, 2007
Last modified: January 22, 2014
This is version 71 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways