Reviewed,
UniProtKB/Swiss-Prot Q75BV4 (LYS1_ASHGO)
Last modified
June 16, 2009.
Version 33.
History...
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90%,
50% identity |
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: Saccharopine dehydrogenase [NAD+, L-lysine-forming] Short name=SDH EC=1.5.1.7 Alternative name(s): Lysine--2-oxoglutarate reductase | ||||
| Gene names |
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| Organism | Ashbya gossypii (Yeast) (Eremothecium gossypii) [Complete proteome] | ||||
| Taxonomic identifier | 33169 [NCBI] | ||||
| Taxonomic lineage | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Eremothecium |
Protein attributes
| Sequence length | 372 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Catalytic activity | N(6)-(L-1,3-dicarboxypropyl)-L-lysine + NAD+ + H2O = L-lysine + 2-oxoglutarate + NADH. |
| Pathway | |
| Subunit structure | Monomer By similarity. |
| Sequence similarities | Belongs to the AlaDH/PNT family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Amino-acid biosynthesis Lysine biosynthesis |
| Ligand | NAD |
| Molecular function | Oxidoreductase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | lysine biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW oxidation reductionInferred from electronic annotation. Source: UniProtKB-KW |
| Molecular function | binding Inferred from electronic annotation. Source: InterPro electron carrier activityInferred from electronic annotation. Source: InterPro saccharopine dehydrogenase (NAD+, L-lysine-forming) activityInferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
Sequences
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References
| [1] | "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces cerevisiae genome." Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S., Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A., Gaffney T.D., Philippsen P. Science 304:304-307(2004) [PubMed: 15001715] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 10895 / NRRL Y-1056 / CBS 109.51. |
Cross-references
Sequence databases | |
|---|---|
| AE016816 Genomic DNA. Translation: AAS51393.1. | |
| RefSeq | NP_983569.1. |
3D structure databases | |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 4619701. |
| KEGG | ago:AGOS_ACR167C. |
| NMPDR | fig|33169.1.peg.1214. |
Organism-specific databases | |
| AGD | ACR167C. |
Phylogenomic databases | |
| HOGENOM | Q75BV4. |
| OMA | Q75BV4. IGALGRC. |
Enzyme and pathway databases | |
| BRENDA | 1.5.1.7. 279361. |
Family and domain databases | |
| InterPro | IPR007698. Ala_DH/PNT_C. IPR007886. Ala_DH/PNT_N. [Graphical view] |
| Pfam | PF01262. AlaDh_PNT_C. 1 hit. PF05222. AlaDh_PNT_N. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | LYS1_ASHGO | ||||||||
| Accession | Primary (citable) accession number: Q75BV4 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | FPAP (Fungal Proteome Annotation Project) | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

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