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Q75B37

- OCA1_ASHGO

UniProt

Q75B37 - OCA1_ASHGO

Protein

Putative tyrosine-protein phosphatase OCA1

Gene

OCA1

Organism
Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 63 (01 Oct 2014)
      Sequence version 1 (05 Jul 2004)
      Previous versions | rss
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    Functioni

    Putative tyrosine-protein phosphatase required for protection against superoxide stress.By similarity

    Catalytic activityi

    Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei138 – 1381Phosphocysteine intermediateBy similarity

    GO - Molecular functioni

    1. protein tyrosine phosphatase activity Source: UniProtKB-EC

    GO - Biological processi

    1. cellular response to oxidative stress Source: EnsemblFungi

    Keywords - Molecular functioni

    Hydrolase, Protein phosphatase

    Keywords - Biological processi

    Stress response

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Putative tyrosine-protein phosphatase OCA1 (EC:3.1.3.48)
    Gene namesi
    Name:OCA1
    Ordered Locus Names:ADL260W
    OrganismiAshbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii)
    Taxonomic identifieri284811 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeEremothecium
    ProteomesiUP000000591: Chromosome IV

    Subcellular locationi

    Cytoplasm By similarity

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 225225Putative tyrosine-protein phosphatase OCA1PRO_0000333388Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi33169.AGOS_ADL260W.

    Structurei

    3D structure databases

    ProteinModelPortaliQ75B37.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG2365.
    HOGENOMiHOG000188365.
    KOiK18043.
    OMAiKLQRWNL.
    OrthoDBiEOG7Z0K6V.

    Family and domain databases

    Gene3Di3.90.190.10. 1 hit.
    InterProiIPR029021. Prot-tyrosine_phosphatase-like.
    IPR020428. Tyr_Pase_dualsp-Pase_euk.
    IPR004861. Tyr_Pase_SIW14-like.
    [Graphical view]
    PfamiPF03162. Y_phosphatase2. 1 hit.
    [Graphical view]
    PRINTSiPR01911. PFDSPHPHTASE.
    SUPFAMiSSF52799. SSF52799. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q75B37-1 [UniParc]FASTAAdd to Basket

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    MTDNCREDDD NLGTSGDNAL SAPTQLLVTP PAPHQTIVPP LNFCPVERYL    50
    YRSGQPSTVN FPFLLNLNLR TIIWLANEEP QDALLAFCDM HDIRLRFAAI 100
    NPEGGEDDNP WDGLTEHSIV SALQTIVHRD NYPLLVCCGM GRHRTGTVIG 150
    CLRRIMGWNL ASVSEEYRRF TGSRGGRILV ELLIEAFDTK SVTIDKANAP 200
    EWLATAVSAS EASYVPATTY SIHEM 225
    Length:225
    Mass (Da):24,960
    Last modified:July 5, 2004 - v1
    Checksum:i7093A43D07072C75
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE016817 Genomic DNA. Translation: AAS51660.1.
    RefSeqiNP_983836.1. NM_209189.1.

    Genome annotation databases

    EnsemblFungiiAAS51660; AAS51660; AGOS_ADL260W.
    GeneIDi4619971.
    KEGGiago:AGOS_ADL260W.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE016817 Genomic DNA. Translation: AAS51660.1 .
    RefSeqi NP_983836.1. NM_209189.1.

    3D structure databases

    ProteinModelPortali Q75B37.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 33169.AGOS_ADL260W.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii AAS51660 ; AAS51660 ; AGOS_ADL260W .
    GeneIDi 4619971.
    KEGGi ago:AGOS_ADL260W.

    Phylogenomic databases

    eggNOGi COG2365.
    HOGENOMi HOG000188365.
    KOi K18043.
    OMAi KLQRWNL.
    OrthoDBi EOG7Z0K6V.

    Family and domain databases

    Gene3Di 3.90.190.10. 1 hit.
    InterProi IPR029021. Prot-tyrosine_phosphatase-like.
    IPR020428. Tyr_Pase_dualsp-Pase_euk.
    IPR004861. Tyr_Pase_SIW14-like.
    [Graphical view ]
    Pfami PF03162. Y_phosphatase2. 1 hit.
    [Graphical view ]
    PRINTSi PR01911. PFDSPHPHTASE.
    SUPFAMi SSF52799. SSF52799. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces cerevisiae genome."
      Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S., Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A., Gaffney T.D., Philippsen P.
      Science 304:304-307(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056.
    2. "Genomes of Ashbya fungi isolated from insects reveal four mating-type loci, numerous translocations, lack of transposons, and distinct gene duplications."
      Dietrich F.S., Voegeli S., Kuo S., Philippsen P.
      G3 (Bethesda) 3:1225-1239(2013) [PubMed] [Europe PMC] [Abstract]
      Cited for: GENOME REANNOTATION.
      Strain: ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056.

    Entry informationi

    Entry nameiOCA1_ASHGO
    AccessioniPrimary (citable) accession number: Q75B37
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 20, 2008
    Last sequence update: July 5, 2004
    Last modified: October 1, 2014
    This is version 63 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3