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Q75B37

- OCA1_ASHGO

UniProt

Q75B37 - OCA1_ASHGO

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Protein
Putative tyrosine-protein phosphatase OCA1
Gene
OCA1, ADL260W
Organism
Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Putative tyrosine-protein phosphatase required for protection against superoxide stress By similarity.

Catalytic activityi

Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei138 – 1381Phosphocysteine intermediate By similarity

GO - Molecular functioni

  1. protein tyrosine phosphatase activity Source: UniProtKB-EC
Complete GO annotation...

GO - Biological processi

  1. cellular response to oxidative stress Source: EnsemblFungi
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Biological processi

Stress response

Names & Taxonomyi

Protein namesi
Recommended name:
Putative tyrosine-protein phosphatase OCA1 (EC:3.1.3.48)
Gene namesi
Name:OCA1
Ordered Locus Names:ADL260W
OrganismiAshbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii)
Taxonomic identifieri284811 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeEremothecium
ProteomesiUP000000591: Chromosome IV

Subcellular locationi

Cytoplasm By similarity

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 225225Putative tyrosine-protein phosphatase OCA1
PRO_0000333388Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi33169.AGOS_ADL260W.

Structurei

3D structure databases

ProteinModelPortaliQ75B37.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG2365.
HOGENOMiHOG000188365.
KOiK18043.
OMAiKLQRWNL.
OrthoDBiEOG7Z0K6V.

Family and domain databases

Gene3Di3.90.190.10. 1 hit.
InterProiIPR029021. Prot-tyrosine_phosphatase-like.
IPR020428. Tyr_Pase_dualsp-Pase_euk.
IPR004861. Tyr_Pase_SIW14-like.
[Graphical view]
PfamiPF03162. Y_phosphatase2. 1 hit.
[Graphical view]
PRINTSiPR01911. PFDSPHPHTASE.
SUPFAMiSSF52799. SSF52799. 1 hit.

Sequencei

Sequence statusi: Complete.

Q75B37-1 [UniParc]FASTAAdd to Basket

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MTDNCREDDD NLGTSGDNAL SAPTQLLVTP PAPHQTIVPP LNFCPVERYL    50
YRSGQPSTVN FPFLLNLNLR TIIWLANEEP QDALLAFCDM HDIRLRFAAI 100
NPEGGEDDNP WDGLTEHSIV SALQTIVHRD NYPLLVCCGM GRHRTGTVIG 150
CLRRIMGWNL ASVSEEYRRF TGSRGGRILV ELLIEAFDTK SVTIDKANAP 200
EWLATAVSAS EASYVPATTY SIHEM 225
Length:225
Mass (Da):24,960
Last modified:July 5, 2004 - v1
Checksum:i7093A43D07072C75
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE016817 Genomic DNA. Translation: AAS51660.1.
RefSeqiNP_983836.1. NM_209189.1.

Genome annotation databases

EnsemblFungiiAAS51660; AAS51660; AGOS_ADL260W.
GeneIDi4619971.
KEGGiago:AGOS_ADL260W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE016817 Genomic DNA. Translation: AAS51660.1 .
RefSeqi NP_983836.1. NM_209189.1.

3D structure databases

ProteinModelPortali Q75B37.
ModBasei Search...

Protein-protein interaction databases

STRINGi 33169.AGOS_ADL260W.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii AAS51660 ; AAS51660 ; AGOS_ADL260W .
GeneIDi 4619971.
KEGGi ago:AGOS_ADL260W.

Phylogenomic databases

eggNOGi COG2365.
HOGENOMi HOG000188365.
KOi K18043.
OMAi KLQRWNL.
OrthoDBi EOG7Z0K6V.

Family and domain databases

Gene3Di 3.90.190.10. 1 hit.
InterProi IPR029021. Prot-tyrosine_phosphatase-like.
IPR020428. Tyr_Pase_dualsp-Pase_euk.
IPR004861. Tyr_Pase_SIW14-like.
[Graphical view ]
Pfami PF03162. Y_phosphatase2. 1 hit.
[Graphical view ]
PRINTSi PR01911. PFDSPHPHTASE.
SUPFAMi SSF52799. SSF52799. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces cerevisiae genome."
    Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S., Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A., Gaffney T.D., Philippsen P.
    Science 304:304-307(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056.
  2. "Genomes of Ashbya fungi isolated from insects reveal four mating-type loci, numerous translocations, lack of transposons, and distinct gene duplications."
    Dietrich F.S., Voegeli S., Kuo S., Philippsen P.
    G3 (Bethesda) 3:1225-1239(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENOME REANNOTATION.
    Strain: ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056.

Entry informationi

Entry nameiOCA1_ASHGO
AccessioniPrimary (citable) accession number: Q75B37
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: July 5, 2004
Last modified: July 9, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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