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Q75B37 (OCA1_ASHGO) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 62. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative tyrosine-protein phosphatase OCA1

EC=3.1.3.48
Gene names
Name:OCA1
Ordered Locus Names:ADL260W
OrganismAshbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii) [Reference proteome]
Taxonomic identifier284811 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeEremothecium

Protein attributes

Sequence length225 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Putative tyrosine-protein phosphatase required for protection against superoxide stress By similarity.

Catalytic activity

Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the protein-tyrosine phosphatase family.

Ontologies

Keywords
   Biological processStress response
   Cellular componentCytoplasm
   Molecular functionHydrolase
Protein phosphatase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processcellular response to oxidative stress

Inferred from electronic annotation. Source: EnsemblFungi

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionprotein tyrosine phosphatase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 225225Putative tyrosine-protein phosphatase OCA1
PRO_0000333388

Sites

Active site1381Phosphocysteine intermediate By similarity

Sequences

Sequence LengthMass (Da)Tools
Q75B37 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: 7093A43D07072C75

FASTA22524,960
        10         20         30         40         50         60 
MTDNCREDDD NLGTSGDNAL SAPTQLLVTP PAPHQTIVPP LNFCPVERYL YRSGQPSTVN 

        70         80         90        100        110        120 
FPFLLNLNLR TIIWLANEEP QDALLAFCDM HDIRLRFAAI NPEGGEDDNP WDGLTEHSIV 

       130        140        150        160        170        180 
SALQTIVHRD NYPLLVCCGM GRHRTGTVIG CLRRIMGWNL ASVSEEYRRF TGSRGGRILV 

       190        200        210        220 
ELLIEAFDTK SVTIDKANAP EWLATAVSAS EASYVPATTY SIHEM 

« Hide

References

« Hide 'large scale' references
[1]"The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces cerevisiae genome."
Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S., Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A., Gaffney T.D., Philippsen P.
Science 304:304-307(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056.
[2]"Genomes of Ashbya fungi isolated from insects reveal four mating-type loci, numerous translocations, lack of transposons, and distinct gene duplications."
Dietrich F.S., Voegeli S., Kuo S., Philippsen P.
G3 (Bethesda) 3:1225-1239(2013) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE016817 Genomic DNA. Translation: AAS51660.1.
RefSeqNP_983836.1. NM_209189.1.

3D structure databases

ProteinModelPortalQ75B37.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING33169.AGOS_ADL260W.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiAAS51660; AAS51660; AGOS_ADL260W.
GeneID4619971.
KEGGago:AGOS_ADL260W.

Phylogenomic databases

eggNOGCOG2365.
HOGENOMHOG000188365.
KOK18043.
OMAKLQRWNL.
OrthoDBEOG7Z0K6V.

Family and domain databases

Gene3D3.90.190.10. 1 hit.
InterProIPR029021. Prot-tyrosine_phosphatase-like.
IPR020428. Tyr_Pase_dualsp-Pase_euk.
IPR004861. Tyr_Pase_SIW14-like.
[Graphical view]
PfamPF03162. Y_phosphatase2. 1 hit.
[Graphical view]
PRINTSPR01911. PFDSPHPHTASE.
SUPFAMSSF52799. SSF52799. 1 hit.
ProtoNetSearch...

Entry information

Entry nameOCA1_ASHGO
AccessionPrimary (citable) accession number: Q75B37
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: July 5, 2004
Last modified: July 9, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families