Reviewed, UniProtKB/Swiss-Prot Q759T3 (BNA7_ASHGO)

Names and origin

Protein names

Recommended name:
    Probable kynurenine formamidase
    EC=3.5.1.9
Alternative name(s):
    Probable N-formylkynurenine formamidase
    Biosynthesis of nicotinic acid protein 7

Gene names

Name:	BNA7
Ordered Locus Names:	ADR190W

Organism

Ashbya gossypii (Yeast) (Eremothecium gossypii) [Complete proteome]

Taxonomic identifier

33169 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Eremothecium

Protein attributes

Sequence length	241 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the conversion of tryptophan to nicotinic acid, NAD(H) and NADP(H) By similarity.
Catalytic activity	N-formyl-L-kynurenine + H2O = formate + L-kynurenine.
Pathway	Amino-acid degradation; L-tryptophan degradation via kynurenine pathway; L-kynurenine from L-tryptophan: step 2/2.
Sequence similarities	Belongs to the BNA7 family.

Ontologies

Keywords
Biological process	Tryptophan catabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tryptophan catabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	arylformamidase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 241	241	Probable kynurenine formamidase		PRO_0000361880
Sites
	Active site	23	1	Potential
	Active site	95	1	Potential

Sequences

	Sequence		Length	Mass (Da)
	Q759T3-1 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: C00B4309ECDD6728	FASTA	241	27,250
	10 20 30 40 50 60 MQRDYTATEV FQESGPDAIV YLHGGAWIDV RNSPRDFAEL AARVREDAPL ASQYAVTYRL 70 80 90 100 110 120 SPEVQHPVHV ADCVEHISQL IVEKGIRKLH LLGHSVGATL CWQILTALPG DRRYPEGPDF 130 140 150 160 170 180 AMKLALVRSS LAHVFLVDGI YSLRALLEEY PDYDYFVNKA FKSLKDFEDP SESAERISAG 190 200 210 220 230 240 PILHVIHSYK DELLTLKQTQ YLTAVLTAHQ IPYKLYVDDL GLHEDVYRNE KVAAYIVAQL P

References

[1]

"The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces cerevisiae genome." Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S., Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A., Gaffney T.D., Philippsen P. Science 304:304-307(2004) [PubMed: 15001715] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 10895 / NRRL Y-1056 / CBS 109.51.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE016817 Genomic DNA. Translation: AAS52110.1.
RefSeq	NP_984286.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	4620448.
GenomeReviews	Gene locus ADR190W in contig AE016817_GR.
KEGG	ago:AGOS_ADR190W.
NMPDR	fig|33169.1.peg.1931.
Organism-specific databases
AGD	ADR190W.
Phylogenomic databases
HOGENOM	Q759T3.
OMA	ERILMNE.
Family and domain databases
ProtoNet	Search...

Entry information

Entry name

BNA7_ASHGO

Accession

Primary (citable) accession number: Q759T3

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 10, 2009
Last sequence update:	July 5, 2004
Last modified:	November 3, 2009
This is version 36 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

FPAP (Fungal Proteome Annotation Project)