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Q758L0 (G6PI_ASHGO) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 64. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucose-6-phosphate isomerase

Short name=GPI
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase
Short name=PGI
Phosphohexose isomerase
Short name=PHI
Gene names
Name:PGI1
Ordered Locus Names:AEL249C
OrganismAshbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii) [Reference proteome]
Taxonomic identifier284811 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeEremothecium

Protein attributes

Sequence length555 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP-Rule MF_00473

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP-Rule MF_00473

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00473.

Sequence similarities

Belongs to the GPI family.

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-KW

glycolysis

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglucose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 555555Glucose-6-phosphate isomerase HAMAP-Rule MF_00473
PRO_0000180570

Sites

Active site3681Proton donor By similarity
Active site3991 By similarity
Active site5211 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q758L0 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: BE12632073654FDD

FASTA55561,257
        10         20         30         40         50         60 
MATTNTFSDF KLASELPAWA KLQELYEKKG KTLSLKEAFA TDEQRFQKYS RTFSNHDGSK 

        70         80         90        100        110        120 
ILFDFSKNLV DDEILGALAQ LAREANVTQL RDQMFNGEHI NSTEDRAVYH VALRNRANKP 

       130        140        150        160        170        180 
MYVDGKNVAP EVDAVLQHMK EFSEQVRSGA WKGYTGKSIK DVVNIGIGGS DLGPVMVTEA 

       190        200        210        220        230        240 
LKHYAGPLKV HFVSNIDGTH LAETLKEVDP ETTLFLVASK TFTTAETITN ATSAKNWFLS 

       250        260        270        280        290        300 
KTGNNPAHIS KHFAALSTNE TEVAKFGIDT KNMFGFESWV GGRYSVWSAI GLSVALYIGF 

       310        320        330        340        350        360 
DQFEDFLKGA EAVDKHFTST PIEDNIPLLG GLLSVWYNNF FDAQTHLVVP FDQYLHRFPA 

       370        380        390        400        410        420 
YLQQLSMESN GKSVTRGNVF ANYSTGSILF GEPATNAQHS FFQLVHQGTK VIPSDFILAA 

       430        440        450        460        470        480 
QSHNPIENNL HQKMLASNFF AQAEALMVGK DEAQVKAEGA TGGLVPHKVF SGNRPTTSIL 

       490        500        510        520        530        540 
VQKITPANLG ALIAYYEHVT FTEGAIWNIN SFDQWGVELG KVLAKVIGKD LDTTGETTSH 

       550 
DASTNGLINQ FKAWL 

« Hide

References

« Hide 'large scale' references
[1]"The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces cerevisiae genome."
Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S., Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A., Gaffney T.D., Philippsen P.
Science 304:304-307(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056.
[2]"Genomes of Ashbya fungi isolated from insects reveal four mating-type loci, numerous translocations, lack of transposons, and distinct gene duplications."
Dietrich F.S., Voegeli S., Kuo S., Philippsen P.
G3 (Bethesda) 3:1225-1239(2013) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE016818 Genomic DNA. Translation: AAS52436.1.
RefSeqNP_984612.1. NM_209965.1.

3D structure databases

ProteinModelPortalQ758L0.
SMRQ758L0. Positions 14-554.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING33169.AGOS_AEL249C.

Proteomic databases

PRIDEQ758L0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiAAS52436; AAS52436; AGOS_AEL249C.
GeneID4620794.
KEGGago:AGOS_AEL249C.

Phylogenomic databases

eggNOGCOG0166.
HOGENOMHOG000261371.
KOK01810.
OMALKMHFVS.
OrthoDBEOG7N0CDV.
PhylomeDBQ758L0.

Enzyme and pathway databases

UniPathwayUPA00109; UER00181.

Family and domain databases

Gene3D1.10.1390.10. 1 hit.
HAMAPMF_00473. G6P_isomerase.
InterProIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERPTHR11469. PTHR11469. 1 hit.
PfamPF00342. PGI. 1 hit.
[Graphical view]
PRINTSPR00662. G6PISOMERASE.
PROSITEPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG6PI_ASHGO
AccessionPrimary (citable) accession number: Q758L0
Entry history
Integrated into UniProtKB/Swiss-Prot: September 27, 2004
Last sequence update: July 5, 2004
Last modified: February 19, 2014
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways