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Protein

1,4-alpha-glucan-branching enzyme

Gene

GLC3

Organism
Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Transfers a segment of a (1->4)-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain.

Pathwayi: glycogen biosynthesis

This protein is involved in the pathway glycogen biosynthesis, which is part of Glycan biosynthesis.
View all proteins of this organism that are known to be involved in the pathway glycogen biosynthesis and in Glycan biosynthesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei355NucleophileBy similarity1
Active sitei415Proton donorBy similarity1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Keywords - Biological processi

Glycogen biosynthesis

Enzyme and pathway databases

UniPathwayiUPA00164.

Protein family/group databases

CAZyiCBM48. Carbohydrate-Binding Module Family 48.
GH13. Glycoside Hydrolase Family 13.

Names & Taxonomyi

Protein namesi
Recommended name:
1,4-alpha-glucan-branching enzyme (EC:2.4.1.18)
Alternative name(s):
Glycogen-branching enzyme
Gene namesi
Name:GLC3
Ordered Locus Names:AEL044W
OrganismiAshbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii)
Taxonomic identifieri284811 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeEremothecium
Proteomesi
  • UP000000591 Componenti: Chromosome V

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001887771 – 7031,4-alpha-glucan-branching enzymeAdd BLAST703

Structurei

3D structure databases

ProteinModelPortaliQ757Q6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

HOGENOMiHOG000175159.
InParanoidiQ757Q6.
KOiK00700.
OMAiEWDMANI.
OrthoDBiEOG092C0QFK.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
InterProiIPR006048. A-amylase/branching_C.
IPR006407. GlgB.
IPR015902. Glyco_hydro_13.
IPR006047. Glyco_hydro_13_cat_dom.
IPR004193. Glyco_hydro_13_N.
IPR013780. Glyco_hydro_b.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
[Graphical view]
PANTHERiPTHR10357. PTHR10357. 1 hit.
PfamiPF00128. Alpha-amylase. 1 hit.
PF02806. Alpha-amylase_C. 1 hit.
PF02922. CBM_48. 1 hit.
[Graphical view]
PIRSFiPIRSF000463. GlgB. 1 hit.
SMARTiSM00642. Aamy. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 2 hits.
SSF81296. SSF81296. 1 hit.

Sequencei

Sequence statusi: Complete.

Q757Q6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGVPDNVKG VVELDPWLAP YGDILSARRF LADKWRHDIE HAVPGGRRSL
60 70 80 90 100
VEFARDAYKS YGLHADAQSK SITYREWAPN ATRAFLVGDF NGWDETSHEL
110 120 130 140 150
QNKDEFGVFT GVFGPGADGD FMIPHDSRVK VVFELADGSR IHRLPAWIKR
160 170 180 190 200
ATQPSKETAK EWGPSYEARF WNPASPYKFK HERPRLDPNV ESLRIYEAHV
210 220 230 240 250
GISTPEPRVG SYSEFTKDVL PRIRDLGYNA IQLMAIMEHA YYASFGYQVT
260 270 280 290 300
NFFAVSSRYG TPEELKELID TAHGMGIQVL LDVVHSHASK NVSDGLNMFD
310 320 330 340 350
GTDYQYFHSI SSGRGEHPLW DSRLFNYGSF EVQRFLLANL AFYIDVYQFD
360 370 380 390 400
GFRFDGVTSM LYHHHGVGER GAFSGDYNEY LSDHSGVDHE ALAYLMLAND
410 420 430 440 450
LIHDMLPANG VTVAEDVSGY PTLCLPRSVG GCGFDYRLAM ALPDMWIKLL
460 470 480 490 500
KESKDEDWSM GHIVYTLVNR RYKEKVVAYA ESHDQALVGD KTLAFWMMDA
510 520 530 540 550
AMYTDMTVLK ELTPVVDRGI ALHKLIRLIT HSLGGESYLN FEGNEFGHPE
560 570 580 590 600
WLDFPNANNG DSYQYARRQF NLVDDGLLRY KHLYAFDKAM QEAEGKHKWL
610 620 630 640 650
NTPQAYVSLK HETDKVISFE RNGLVFIFNF HPTQSFTDYR IGVDEAGAYR
660 670 680 690 700
IILNSDREEF GGHRRIEEEN SVFHTTDLEW NGRRNFIQVY LPSRTALVLA

RNP
Length:703
Mass (Da):80,263
Last modified:July 5, 2004 - v1
Checksum:iB41AE8250252DBF4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016818 Genomic DNA. Translation: AAS52641.1.
RefSeqiNP_984817.1. NM_210171.1.

Genome annotation databases

EnsemblFungiiAAS52641; AAS52641; AGOS_AEL044W.
GeneIDi4621011.
KEGGiago:AGOS_AEL044W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016818 Genomic DNA. Translation: AAS52641.1.
RefSeqiNP_984817.1. NM_210171.1.

3D structure databases

ProteinModelPortaliQ757Q6.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

CAZyiCBM48. Carbohydrate-Binding Module Family 48.
GH13. Glycoside Hydrolase Family 13.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiAAS52641; AAS52641; AGOS_AEL044W.
GeneIDi4621011.
KEGGiago:AGOS_AEL044W.

Phylogenomic databases

HOGENOMiHOG000175159.
InParanoidiQ757Q6.
KOiK00700.
OMAiEWDMANI.
OrthoDBiEOG092C0QFK.

Enzyme and pathway databases

UniPathwayiUPA00164.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
InterProiIPR006048. A-amylase/branching_C.
IPR006407. GlgB.
IPR015902. Glyco_hydro_13.
IPR006047. Glyco_hydro_13_cat_dom.
IPR004193. Glyco_hydro_13_N.
IPR013780. Glyco_hydro_b.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
[Graphical view]
PANTHERiPTHR10357. PTHR10357. 1 hit.
PfamiPF00128. Alpha-amylase. 1 hit.
PF02806. Alpha-amylase_C. 1 hit.
PF02922. CBM_48. 1 hit.
[Graphical view]
PIRSFiPIRSF000463. GlgB. 1 hit.
SMARTiSM00642. Aamy. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 2 hits.
SSF81296. SSF81296. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiGLGB_ASHGO
AccessioniPrimary (citable) accession number: Q757Q6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 10, 2005
Last sequence update: July 5, 2004
Last modified: September 7, 2016
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.