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Protein

1,4-alpha-glucan-branching enzyme

Gene

GLC3

Organism
Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Transfers a segment of a (1->4)-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei355 – 3551NucleophileBy similarity
Active sitei415 – 4151Proton donorBy similarity

GO - Molecular functioni

  1. 1,4-alpha-glucan branching enzyme activity Source: UniProtKB-EC
  2. cation binding Source: InterPro
  3. hydrolase activity, hydrolyzing O-glycosyl compounds Source: InterPro

GO - Biological processi

  1. glycogen biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Keywords - Biological processi

Glycogen biosynthesis

Enzyme and pathway databases

UniPathwayiUPA00164.

Names & Taxonomyi

Protein namesi
Recommended name:
1,4-alpha-glucan-branching enzyme (EC:2.4.1.18)
Alternative name(s):
Glycogen-branching enzyme
Gene namesi
Name:GLC3
Ordered Locus Names:AEL044W
OrganismiAshbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii)
Taxonomic identifieri284811 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeEremothecium
ProteomesiUP000000591: Chromosome V

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: EnsemblFungi
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 7037031,4-alpha-glucan-branching enzymePRO_0000188777Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi33169.AGOS_AEL044W.

Structurei

3D structure databases

ProteinModelPortaliQ757Q6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0296.
HOGENOMiHOG000175159.
InParanoidiQ757Q6.
KOiK00700.
OMAiWTHIYIP.
OrthoDBiEOG7647B5.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
InterProiIPR006048. A-amylase_b_C.
IPR006407. GlgB.
IPR015902. Glyco_hydro_13.
IPR013780. Glyco_hydro_13_b.
IPR006047. Glyco_hydro_13_cat_dom.
IPR004193. Glyco_hydro_13_N.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
[Graphical view]
PANTHERiPTHR10357. PTHR10357. 1 hit.
PfamiPF00128. Alpha-amylase. 1 hit.
PF02806. Alpha-amylase_C. 1 hit.
PF02922. CBM_48. 1 hit.
[Graphical view]
PIRSFiPIRSF000463. GlgB. 1 hit.
SUPFAMiSSF51445. SSF51445. 2 hits.
SSF81296. SSF81296. 1 hit.

Sequencei

Sequence statusi: Complete.

Q757Q6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGVPDNVKG VVELDPWLAP YGDILSARRF LADKWRHDIE HAVPGGRRSL
60 70 80 90 100
VEFARDAYKS YGLHADAQSK SITYREWAPN ATRAFLVGDF NGWDETSHEL
110 120 130 140 150
QNKDEFGVFT GVFGPGADGD FMIPHDSRVK VVFELADGSR IHRLPAWIKR
160 170 180 190 200
ATQPSKETAK EWGPSYEARF WNPASPYKFK HERPRLDPNV ESLRIYEAHV
210 220 230 240 250
GISTPEPRVG SYSEFTKDVL PRIRDLGYNA IQLMAIMEHA YYASFGYQVT
260 270 280 290 300
NFFAVSSRYG TPEELKELID TAHGMGIQVL LDVVHSHASK NVSDGLNMFD
310 320 330 340 350
GTDYQYFHSI SSGRGEHPLW DSRLFNYGSF EVQRFLLANL AFYIDVYQFD
360 370 380 390 400
GFRFDGVTSM LYHHHGVGER GAFSGDYNEY LSDHSGVDHE ALAYLMLAND
410 420 430 440 450
LIHDMLPANG VTVAEDVSGY PTLCLPRSVG GCGFDYRLAM ALPDMWIKLL
460 470 480 490 500
KESKDEDWSM GHIVYTLVNR RYKEKVVAYA ESHDQALVGD KTLAFWMMDA
510 520 530 540 550
AMYTDMTVLK ELTPVVDRGI ALHKLIRLIT HSLGGESYLN FEGNEFGHPE
560 570 580 590 600
WLDFPNANNG DSYQYARRQF NLVDDGLLRY KHLYAFDKAM QEAEGKHKWL
610 620 630 640 650
NTPQAYVSLK HETDKVISFE RNGLVFIFNF HPTQSFTDYR IGVDEAGAYR
660 670 680 690 700
IILNSDREEF GGHRRIEEEN SVFHTTDLEW NGRRNFIQVY LPSRTALVLA

RNP
Length:703
Mass (Da):80,263
Last modified:July 5, 2004 - v1
Checksum:iB41AE8250252DBF4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016818 Genomic DNA. Translation: AAS52641.1.
RefSeqiNP_984817.1. NM_210171.1.

Genome annotation databases

EnsemblFungiiAAS52641; AAS52641; AGOS_AEL044W.
GeneIDi4621011.
KEGGiago:AGOS_AEL044W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016818 Genomic DNA. Translation: AAS52641.1.
RefSeqiNP_984817.1. NM_210171.1.

3D structure databases

ProteinModelPortaliQ757Q6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi33169.AGOS_AEL044W.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiAAS52641; AAS52641; AGOS_AEL044W.
GeneIDi4621011.
KEGGiago:AGOS_AEL044W.

Phylogenomic databases

eggNOGiCOG0296.
HOGENOMiHOG000175159.
InParanoidiQ757Q6.
KOiK00700.
OMAiWTHIYIP.
OrthoDBiEOG7647B5.

Enzyme and pathway databases

UniPathwayiUPA00164.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
InterProiIPR006048. A-amylase_b_C.
IPR006407. GlgB.
IPR015902. Glyco_hydro_13.
IPR013780. Glyco_hydro_13_b.
IPR006047. Glyco_hydro_13_cat_dom.
IPR004193. Glyco_hydro_13_N.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
[Graphical view]
PANTHERiPTHR10357. PTHR10357. 1 hit.
PfamiPF00128. Alpha-amylase. 1 hit.
PF02806. Alpha-amylase_C. 1 hit.
PF02922. CBM_48. 1 hit.
[Graphical view]
PIRSFiPIRSF000463. GlgB. 1 hit.
SUPFAMiSSF51445. SSF51445. 2 hits.
SSF81296. SSF81296. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces cerevisiae genome."
    Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S., Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A., Gaffney T.D., Philippsen P.
    Science 304:304-307(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056.
  2. "Genomes of Ashbya fungi isolated from insects reveal four mating-type loci, numerous translocations, lack of transposons, and distinct gene duplications."
    Dietrich F.S., Voegeli S., Kuo S., Philippsen P.
    G3 (Bethesda) 3:1225-1239(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENOME REANNOTATION.
    Strain: ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056.

Entry informationi

Entry nameiGLGB_ASHGO
AccessioniPrimary (citable) accession number: Q757Q6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 10, 2005
Last sequence update: July 5, 2004
Last modified: January 7, 2015
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.