Reviewed,
UniProtKB/Swiss-Prot Q757Q0 (PGK_ASHGO)
Last modified
January 19, 2010.
Version 35.
History...
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90%,
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: Phosphoglycerate kinase EC=2.7.2.3 | ||||
| Gene names |
| ||||
| Organism | Ashbya gossypii (Yeast) (Eremothecium gossypii) [Complete proteome] | ||||
| Taxonomic identifier | 33169 [NCBI] | ||||
| Taxonomic lineage | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Eremothecium |
Protein attributes
| Sequence length | 415 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Catalytic activity | ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate. |
| Subunit structure | Monomer By similarity. |
| Subcellular location | Cytoplasm By similarity. |
| Sequence similarities | Belongs to the phosphoglycerate kinase family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Glycolysis |
| Cellular component | Cytoplasm |
| Ligand | ATP-binding Nucleotide-binding |
| Molecular function | Kinase Transferase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | glycolysis Inferred from electronic annotation. Source: UniProtKB-KW |
| Cellular component | cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | ATP binding Inferred from electronic annotation. Source: UniProtKB-KW phosphoglycerate kinase activityInferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 415 | 415 | Phosphoglycerate kinase | PRO_0000145874 | |||||
Regions | |||||||||
| Nucleotide binding | 370 – 373 | 4 | ATP By similarity | ||||||
| Region | 24 – 26 | 3 | Substrate binding By similarity | ||||||
| Region | 63 – 66 | 4 | Substrate binding By similarity | ||||||
Sites | |||||||||
| Binding site | 39 | 1 | Substrate By similarity | ||||||
| Binding site | 121 | 1 | Substrate By similarity | ||||||
| Binding site | 168 | 1 | Substrate By similarity | ||||||
| Binding site | 217 | 1 | ATP By similarity | ||||||
| Binding site | 310 | 1 | ATP; via carbonyl oxygen By similarity | ||||||
| Binding site | 341 | 1 | ATP By similarity | ||||||
Sequences
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References
| [1] | "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces cerevisiae genome." Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S., Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A., Gaffney T.D., Philippsen P. Science 304:304-307(2004) [PubMed: 15001715] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | AE016818 Genomic DNA. Translation: AAS52647.1. Different initiation. |
| RefSeq | NP_984823.1. |
3D structure databases | |
| SMR | Q757Q0. Positions 2-415. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | Q757Q0. |
Proteomic databases | |
| PRIDE | Q757Q0. |
Genome annotation databases | |
| GeneID | 4621019. |
| GenomeReviews | Gene locus AEL038C in contig AE016818_GR. |
| KEGG | ago:AGOS_AEL038C. |
| NMPDR | fig|33169.1.peg.2468. |
Organism-specific databases | |
| AGD | AEL038C. |
Phylogenomic databases | |
| eggNOG | fuNOG05383. |
| HOGENOM | HBG453500. |
| OrthoDB | EOG9908S2. |
Enzyme and pathway databases | |
| BRENDA | 2.7.2.3. 279361. |
Family and domain databases | |
| InterPro | IPR001576. Phosphoglycerate_kinase. IPR015901. Phosphoglycerate_kinase_C. IPR015911. Phosphoglycerate_kinase_CS. IPR015824. Phosphoglycerate_kinase_N. [Graphical view] |
| Gene3D | G3DSA:3.40.50.1270. Phosphoglycerate_kinase_C. 1 hit. G3DSA:3.40.50.1260. Phosphoglycerate_kinase_N. 1 hit. |
| PANTHER | PTHR11406. PGK. 1 hit. |
| Pfam | PF00162. PGK. 1 hit. [Graphical view] |
| PRINTS | PR00477. PHGLYCKINASE. |
| PROSITE | PS00111. PGLYCERATE_KINASE. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | PGK_ASHGO | ||||||||
| Accession | Primary (citable) accession number: Q757Q0 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | FPAP (Fungal Proteome Annotation Project) | ||||||||

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