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Q757Q0 (PGK_ASHGO) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 50. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphoglycerate kinase
EC=2.7.2.3
Gene names
Name:PGK1
Ordered Locus Names:AEL038C
OrganismAshbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii) [Complete proteome]
Taxonomic identifier284811 [NCBI]
Taxonomic lineageEukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Eremothecium

Protein attributes

Sequence length415 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.

Subunit structure

Monomer By similarity.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the phosphoglycerate kinase family.

Sequence caution

The sequence AAS52647.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
   Biological processGlycolysis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processglycolysis

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

phosphoglycerate kinase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 415415Phosphoglycerate kinase
PRO_0000145874

Regions

Nucleotide binding370 – 3734ATP By similarity
Region24 – 263Substrate binding By similarity
Region63 – 664Substrate binding By similarity

Sites

Binding site391Substrate By similarity
Binding site1211Substrate By similarity
Binding site1681Substrate By similarity
Binding site2171ATP By similarity
Binding site3101ATP; via carbonyl oxygen By similarity
Binding site3411ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q757Q0 [UniParc].

Last modified September 27, 2004. Version 2.
Checksum: B3A6351D878CFBAD

FASTA41544,169
        10         20         30         40         50         60 
MSLSSKLTVK DLSLAGKRVF IRVDFNVPLD GKTITSNQRI VAALPTIKYV LEQGPKAVVL 

        70         80         90        100        110        120 
ASHLGRPNGE RNEKYSLAPV AAELEKLLGQ KVNSWTLRGQ HVTAAVNGAA AGSVFLLENL 

       130        140        150        160        170        180 
RFHIEEEGSR KVDGEKVKAS AEDVQKFRQG LMSLADVYVN DAFGTAHRAH SSMVGFELPE 

       190        200        210        220        230        240 
RAGGFLLSRE LEYFSKALEN PTRPFLAILG GAKVADKIQL IDNLLDKVDS IVIGGGMAFT 

       250        260        270        280        290        300 
FKKVLENMEI GNSIYDKAGA EIVPKLAEKA KKNGVKIVLP VDFVIGDDFS QDANTKIVSA 

       310        320        330        340        350        360 
SEGIPSGWEG LDCGPESRKL FSETIASAKT IVWNGPPGVF EIPKFSEGTQ AMLAAAVKAS 

       370        380        390        400        410 
EAGSTVIIGG GDTATVAKKY GVVEKISHVS TGGGASLELL EGKDLPGVTF LSSKQ

« Hide

References

[1]"The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces cerevisiae genome."
Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S., Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A., Gaffney T.D., Philippsen P.
Science 304:304-307(2004) [PubMed: 15001715] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE016818 Genomic DNA. Translation: AAS52647.1. Different initiation.
RefSeqNP_984823.2. NM_210177.2.

3D structure databases

ProteinModelPortalQ757Q0.
SMRQ757Q0. Positions 2-415.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ757Q0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4621019.
GenomeReviewsGene locus AEL038C in contig AE016818_GR.
KEGGago:AGOS_AEL038C.
NMPDRfig|33169.1.peg.2468.

Organism-specific databases

AGDAEL038C.

Phylogenomic databases

eggNOGfuNOG05383.
HOGENOMHBG453500.
OrthoDBEOG4F4WKK.
PhylomeDBQ757Q0.

Family and domain databases

InterProIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
Gene3DG3DSA:3.40.50.1270. Phosphoglycerate_kinase_C. 1 hit.
G3DSA:3.40.50.1260. Phosphoglycerate_kinase_N. 1 hit.
KOK00927.
PANTHERPTHR11406. PGK. 1 hit.
PfamPF00162. PGK. 1 hit.
[Graphical view]
PIRSFPIRSF000724. Pgk. 1 hit.
PRINTSPR00477. PHGLYCKINASE.
SUPFAMSSF53748. PGK. 1 hit.
PROSITEPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePGK_ASHGO
AccessionPrimary (citable) accession number: Q757Q0
Entry history
Integrated into UniProtKB/Swiss-Prot: September 27, 2004
Last sequence update: September 27, 2004
Last modified: December 14, 2011
This is version 50 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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