Q757F0 (COX9_ASHGO) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Cytochrome c oxidase subunit 7A
EC=1.9.3.1

Alternative name(s):
Cytochrome c oxidase polypeptide VIIA

Gene names

Name:	COX9
Ordered Locus Names:	AER063W

Organism

Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii) [Reference proteome]

Taxonomic identifier

284811 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Eremothecium › Ashbya gossypii

Protein attributes

Sequence length	60 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Function	This small integral protein plays a role in holoenzyme assembly or stability By similarity.
Catalytic activity	4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.
Subunit structure	Composed of at least 11 subunits By similarity.
Subcellular location	Mitochondrion inner membrane By similarity.

Ontologies

Keywords
Cellular component	Membrane Mitochondrion Mitochondrion inner membrane
Domain	Transmembrane Transmembrane helix
Molecular function	Oxidoreductase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	mitochondrial electron transport, cytochrome c to oxygen Inferred from electronic annotation. Source: EnsemblFungi
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW mitochondrial respiratory chain complex IV Inferred from electronic annotation. Source: EnsemblFungi
Molecular_function	cytochrome-c oxidase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Initiator methionine	1	1	Removed By similarity
	Chain	2 – 57	56	Cytochrome c oxidase subunit 7A		PRO_0000041763
	Propeptide	58 – 60	3	Removed in mature form By similarity		PRO_0000041764
Regions
	Transmembrane	19 – 37	19	Helical; Potential

Sequences

	Sequence		Length	Mass (Da)
	Q757F0 [UniParc]. Last modified January 23, 2007. Version 3. Checksum: 7089BF0AA36815B6	FASTA	60	6,714
	10 20 30 40 50 60 MSAIAPITGS LKKRIMKDIA VGMGLGTVLG SYWWWGFHKP KIAARENYYT QLAEQKAAEE

References

[1]

"The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces cerevisiae genome." Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S., Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A., Gaffney T.D., Philippsen P. Science 304:304-307(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE016818 Genomic DNA. Translation: AAS52747.1.
RefSeq	NP_984923.1. NM_210277.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	33169.AGOS_AER063W.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	AAS52747; AAS52747; AGOS_AER063W.
GeneID	4621126.
KEGG	ago:AGOS_AER063W.
Phylogenomic databases
eggNOG	NOG82857.
HOGENOM	HOG000199609.
KO	K02269.
OMA	YAKLEDQ.
OrthoDB	EOG42NN97.
PhylomeDB	Q757F0.
Family and domain databases
InterPro	IPR014368. Cyt_c_oxidase_su7a_fun. [Graphical view]
PIRSF	PIRSF000283. COX9. 1 hit.
ProtoNet	Search...

Entry information

Entry name

COX9_ASHGO

Accession

Primary (citable) accession number: Q757F0

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 13, 2005
Last sequence update:	January 23, 2007
Last modified:	May 1, 2013
This is version 63 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program