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Protein

Cytochrome c oxidase subunit 7A

Gene

COX9

Organism
Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

This small integral protein plays a role in holoenzyme assembly or stability.By similarity

Catalytic activityi

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

GO - Molecular functioni

  1. cytochrome-c oxidase activity Source: UniProtKB-EC

GO - Biological processi

  1. mitochondrial electron transport, cytochrome c to oxygen Source: EnsemblFungi
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c oxidase subunit 7A (EC:1.9.3.1)
Alternative name(s):
Cytochrome c oxidase polypeptide VIIA
Gene namesi
Name:COX9
Ordered Locus Names:AER063W
OrganismiAshbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii)
Taxonomic identifieri284811 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeEremothecium
ProteomesiUP000000591 Componenti: Chromosome V

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei19 – 3719HelicalSequence AnalysisAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. mitochondrial respiratory chain complex IV Source: EnsemblFungi
Complete GO annotation...

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11RemovedBy similarity
Chaini2 – 5756Cytochrome c oxidase subunit 7APRO_0000041763Add
BLAST
Propeptidei58 – 603Removed in mature formBy similarityPRO_0000041764

Interactioni

Subunit structurei

Composed of at least 11 subunits.By similarity

Protein-protein interaction databases

STRINGi33169.AGOS_AER063W.

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG82857.
HOGENOMiHOG000199609.
InParanoidiQ757F0.
KOiK02269.
OMAiKREAYYA.
OrthoDBiEOG7QRR7G.

Family and domain databases

InterProiIPR014368. Cyt_c_oxidase_su7a_fun.
[Graphical view]
PIRSFiPIRSF000283. COX9. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q757F0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSAIAPITGS LKKRIMKDIA VGMGLGTVLG SYWWWGFHKP KIAARENYYT
60
QLAEQKAAEE
Length:60
Mass (Da):6,714
Last modified:January 23, 2007 - v3
Checksum:i7089BF0AA36815B6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016818 Genomic DNA. Translation: AAS52747.1.
RefSeqiNP_984923.1. NM_210277.1.

Genome annotation databases

EnsemblFungiiAAS52747; AAS52747; AGOS_AER063W.
GeneIDi4621126.
KEGGiago:AGOS_AER063W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016818 Genomic DNA. Translation: AAS52747.1.
RefSeqiNP_984923.1. NM_210277.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi33169.AGOS_AER063W.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiAAS52747; AAS52747; AGOS_AER063W.
GeneIDi4621126.
KEGGiago:AGOS_AER063W.

Phylogenomic databases

eggNOGiNOG82857.
HOGENOMiHOG000199609.
InParanoidiQ757F0.
KOiK02269.
OMAiKREAYYA.
OrthoDBiEOG7QRR7G.

Family and domain databases

InterProiIPR014368. Cyt_c_oxidase_su7a_fun.
[Graphical view]
PIRSFiPIRSF000283. COX9. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces cerevisiae genome."
    Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S., Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A., Gaffney T.D., Philippsen P.
    Science 304:304-307(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056.
  2. "Genomes of Ashbya fungi isolated from insects reveal four mating-type loci, numerous translocations, lack of transposons, and distinct gene duplications."
    Dietrich F.S., Voegeli S., Kuo S., Philippsen P.
    G3 (Bethesda) 3:1225-1239(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENOME REANNOTATION.
    Strain: ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056.

Entry informationi

Entry nameiCOX9_ASHGO
AccessioniPrimary (citable) accession number: Q757F0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 13, 2005
Last sequence update: January 23, 2007
Last modified: January 7, 2015
This is version 74 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.