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Q754A0

- Q754A0_ASHGO

UniProt

Q754A0 - Q754A0_ASHGO

Protein

Histone deacetylase

Gene

AFR172C

Organism
Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 76 (01 Oct 2014)
      Sequence version 1 (05 Jul 2004)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Hydrolysis of an N(6)-acetyl-lysine residue of a histone to yield a deacetylated histone.UniRule annotation

    GO - Molecular functioni

    1. NAD-dependent histone deacetylase activity (H3-K14 specific) Source: UniProtKB-EC
    2. NAD-dependent histone deacetylase activity (H3-K18 specific) Source: UniProtKB-EC
    3. NAD-dependent histone deacetylase activity (H3-K9 specific) Source: UniProtKB-EC
    4. NAD-dependent histone deacetylase activity (H4-K16 specific) Source: UniProtKB-EC

    GO - Biological processi

    1. regulation of transcription, DNA-templated Source: UniProtKB-KW
    2. transcription, DNA-templated Source: UniProtKB-KW

    Keywords - Molecular functioni

    Chromatin regulatorUniRule annotation, HydrolaseUniRule annotationSAAS annotation

    Keywords - Biological processi

    Transcription, Transcription regulationUniRule annotation

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Histone deacetylaseUniRule annotation (EC:3.5.1.98UniRule annotation)
    Gene namesi
    Ordered Locus Names:AFR172CImported
    ORF Names:AGOS_AFR172CImported
    OrganismiAshbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii)Imported
    Taxonomic identifieri284811 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeEremothecium
    ProteomesiUP000000591: Chromosome VI

    Subcellular locationi

    Nucleus UniRule annotation

    GO - Cellular componenti

    1. nucleus Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    NucleusUniRule annotation

    Interactioni

    Protein-protein interaction databases

    STRINGi33169.AGOS_AFR172C.

    Structurei

    3D structure databases

    ProteinModelPortaliQ754A0.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the histone deacetylase family. HD Type 1 subfamily.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000225180.
    KOiK11483.
    OMAiARIWLEM.
    OrthoDBiEOG78M0B2.

    Family and domain databases

    Gene3Di3.40.800.20. 1 hit.
    InterProiIPR000286. His_deacetylse.
    IPR003084. His_deacetylse_1.
    IPR023801. His_deacetylse_dom.
    [Graphical view]
    PANTHERiPTHR10625. PTHR10625. 1 hit.
    PfamiPF00850. Hist_deacetyl. 1 hit.
    [Graphical view]
    PIRSFiPIRSF037913. His_deacetylse_1. 1 hit.
    PRINTSiPR01270. HDASUPER.
    PR01271. HISDACETLASE.

    Sequencei

    Sequence statusi: Complete.

    Q754A0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSQTFSYDAK TVNEQPLFEF GASYTPRVSY HYNSRVSQYH YGVRHPMKPF    50
    RLMLTDHLVS RYGLHKVMDL YETRAATKEE VLAFHAQDYV DFLSHVAPEN 100
    LNKLPRGSLE KFNIGDDCPI FQGLFEYSML YAGASLDASR KLINGQSEIA 150
    INWSGGLHHA KKSNPSGFCY VNDIVLAILN LLRYHPRVLY IDIDLHHGDG 200
    VQEAFYTTDR VFTVSFHKYN GEFFPGTGDL DEIGCSRGKH FSLNVPLNDG 250
    IDDDSYINLF KSIIDPLVTS YKPTVIIQQC GADSLGHDRL GCFNLNIRAH 300
    GECVKFVKSF GIPMLCVGGG GYTPRNVSRL WTYETGILND VLLPSDIPED 350
    IPFREWFGPD YSLHPVLDDL YENKNSKKYL ENIRIRCLEN IKYLQGAPSV 400
    RMDAELIPTQ DLPGLTEEEE DLIRELNQED DSYRLEQIEK DNVRRGELL 449
    Length:449
    Mass (Da):51,247
    Last modified:July 5, 2004 - v1
    Checksum:i122BA376FBA4129B
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE016819 Genomic DNA. Translation: AAS53543.1.
    RefSeqiNP_985719.1. NM_211073.1.

    Genome annotation databases

    EnsemblFungiiAAS53543; AAS53543; AGOS_AFR172C.
    GeneIDi4621976.
    KEGGiago:AGOS_AFR172C.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE016819 Genomic DNA. Translation: AAS53543.1 .
    RefSeqi NP_985719.1. NM_211073.1.

    3D structure databases

    ProteinModelPortali Q754A0.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 33169.AGOS_AFR172C.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii AAS53543 ; AAS53543 ; AGOS_AFR172C .
    GeneIDi 4621976.
    KEGGi ago:AGOS_AFR172C.

    Phylogenomic databases

    HOGENOMi HOG000225180.
    KOi K11483.
    OMAi ARIWLEM.
    OrthoDBi EOG78M0B2.

    Family and domain databases

    Gene3Di 3.40.800.20. 1 hit.
    InterProi IPR000286. His_deacetylse.
    IPR003084. His_deacetylse_1.
    IPR023801. His_deacetylse_dom.
    [Graphical view ]
    PANTHERi PTHR10625. PTHR10625. 1 hit.
    Pfami PF00850. Hist_deacetyl. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF037913. His_deacetylse_1. 1 hit.
    PRINTSi PR01270. HDASUPER.
    PR01271. HISDACETLASE.
    ProtoNeti Search...

    Publicationsi

    1. "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces cerevisiae genome."
      Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S., Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A., Gaffney T.D., Philippsen P.
      Science 304:304-307(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056Imported.
    2. "Genomes of Ashbya fungi isolated from insects reveal four mating-type loci, numerous translocations, lack of transposons, and distinct gene duplications."
      Dietrich F.S., Voegeli S., Kuo S., Philippsen P.
      G3 (Bethesda) 3:1225-1239(2013) [PubMed] [Europe PMC] [Abstract]
      Cited for: GENOME REANNOTATION.
      Strain: ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056Imported.

    Entry informationi

    Entry nameiQ754A0_ASHGO
    AccessioniPrimary (citable) accession number: Q754A0
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 5, 2004
    Last sequence update: July 5, 2004
    Last modified: October 1, 2014
    This is version 76 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3