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Q752Y3 (ALO_ASHGO) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 67. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
D-arabinono-1,4-lactone oxidase

Short name=ALO
EC=1.1.3.37
Alternative name(s):
L-galactono-gamma-lactone oxidase
Gene names
Name:ALO1
Ordered Locus Names:AFR440C
OrganismAshbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii) [Reference proteome]
Taxonomic identifier284811 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeEremothecium

Protein attributes

Sequence length532 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-arabinono-1,4-lactone + O2 = dehydro-D-arabinono-1,4-lactone + H2O2.

Cofactor

FAD By similarity.

Pathway

Cofactor biosynthesis; D-erythroascorbate biosynthesis; dehydro-D-arabinono-1,4-lactone from D-arabinose: step 2/2.

Subcellular location

Mitochondrion membrane By similarity. Note: Membrane-embedded By similarity.

Sequence similarities

Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

Contains 1 FAD-binding PCMH-type domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 532532D-arabinono-1,4-lactone oxidase
PRO_0000128163

Regions

Domain25 – 199175FAD-binding PCMH-type

Amino acid modifications

Modified residue621Pros-8alpha-FAD histidine By similarity

Sequences

Sequence LengthMass (Da)Tools
Q752Y3 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: 8B975E346283331C

FASTA53259,965
        10         20         30         40         50         60 
MSVLAGVEAS GIARNYVFKN WAGIYSARPR LYFQPRSEDE VVAIVRAARE QGRTIVTVGS 

        70         80         90        100        110        120 
GHSPSDMCAT DDWMVNLDRL NGVLELQEDE QGRYADVTVA AGIRVYELHR YLSARGYALQ 

       130        140        150        160        170        180 
NLGSISEQSV GGIISTGTHG SSPYHGLVSS QYVNLTLVNG RGELVFLDSE HEPEVFRAAM 

       190        200        210        220        230        240 
LSLGKLGIIV RATIRVVPAF NIHSTQEVIN FETLLDNWET IWTSSEFIRC WWYPYVRKCV 

       250        260        270        280        290        300 
LWRGVKTSEP AEKSRSSWWG TTLGRLVYES LLWLTVNVYP SLTPFVERFI FRQQYGKVET 

       310        320        330        340        350        360 
FGNGDEAVQT SIDGLNMDCL FSQFVDEWAC PLNNGPEVLR SLDHSIAQAA QNKEFFVHVP 

       370        380        390        400        410        420 
IEVRCSNTTL PHEYKCPEDR TVTAPGPVYG NLLRPYLDNT PSHLRYAPLS DVTNSQLTLY 

       430        440        450        460        470        480 
INATIYRPFG TNTPIHKWFT LFEDTLGAAG GKPHWAKNFL GSTATAAGPV KSSDEYQDYE 

       490        500        510        520        530 
MRGMATKIKE WYGDNLKQFQ KVRREQDPHN VFIANKDWAV KNGIIDIDEL DS 

« Hide

References

« Hide 'large scale' references
[1]"The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces cerevisiae genome."
Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S., Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A., Gaffney T.D., Philippsen P.
Science 304:304-307(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056.
[2]"Genomes of Ashbya fungi isolated from insects reveal four mating-type loci, numerous translocations, lack of transposons, and distinct gene duplications."
Dietrich F.S., Voegeli S., Kuo S., Philippsen P.
G3 (Bethesda) 3:1225-1239(2013) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE016819 Genomic DNA. Translation: AAS53811.1.
RefSeqNP_985987.1. NM_211342.1.

3D structure databases

ProteinModelPortalQ752Y3.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING33169.AGOS_AFR440C.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiAAS53811; AAS53811; AGOS_AFR440C.
GeneID4622264.
KEGGago:AGOS_AFR440C.

Phylogenomic databases

eggNOGCOG0277.
HOGENOMHOG000204635.
KOK00107.
OMAMDCLFSQ.
OrthoDBEOG7JX3CZ.

Enzyme and pathway databases

UniPathwayUPA00771; UER00766.

Family and domain databases

Gene3D3.30.43.10. 1 hit.
3.30.465.10. 1 hit.
InterProIPR007173. ALO.
IPR016169. CO_DH_flavot_FAD-bd_sub2.
IPR016166. FAD-bd_2.
IPR016167. FAD-bd_2_sub1.
IPR010031. FAD_lactone_oxidase.
IPR023595. LGO_GLO.
IPR006094. Oxid_FAD_bind_N.
IPR006093. Oxy_OxRdtase_FAD_BS.
[Graphical view]
PfamPF04030. ALO. 1 hit.
PF01565. FAD_binding_4. 1 hit.
[Graphical view]
PIRSFPIRSF000136. LGO_GLO. 1 hit.
SUPFAMSSF56176. SSF56176. 1 hit.
TIGRFAMsTIGR01678. FAD_lactone_ox. 1 hit.
PROSITEPS51387. FAD_PCMH. 1 hit.
PS00862. OX2_COVAL_FAD. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameALO_ASHGO
AccessionPrimary (citable) accession number: Q752Y3
Entry history
Integrated into UniProtKB/Swiss-Prot: November 23, 2004
Last sequence update: July 5, 2004
Last modified: July 9, 2014
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways