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Protein

Sterol 3-beta-glucosyltransferase

Gene

ATG26

Organism
Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Probable sterol 3-beta-glucosyltransferase that is not involved in cytoplasm to vacuole transport (Cvt), pexophagy or nonselective autophagy (By similarity).By similarity

Catalytic activityi

UDP-glucose + a sterol = UDP + a sterol 3-beta-D-glucoside.Curated

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferase, Transferase
Biological processLipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism

Protein family/group databases

CAZyiGT1 Glycosyltransferase Family 1

Names & Taxonomyi

Protein namesi
Recommended name:
Sterol 3-beta-glucosyltransferaseCurated (EC:2.4.1.173Curated)
Alternative name(s):
Autophagy-related protein 26By similarity
Gene namesi
Name:ATG26By similarity
Ordered Locus Names:AFR681W
OrganismiAshbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii)
Taxonomic identifieri284811 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeEremothecium
Proteomesi
  • UP000000591 Componenti: Chromosome VI

Subcellular locationi

Keywords - Cellular componenti

Cytoplasm, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002156061 – 1227Sterol 3-beta-glucosyltransferaseAdd BLAST1227

Interactioni

Protein-protein interaction databases

STRINGi33169.AAS54053

Structurei

3D structure databases

ProteinModelPortaliQ751Z4
SMRiQ751Z4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini188 – 229GRAM 1Sequence analysisAdd BLAST42
Domaini239 – 342PHPROSITE-ProRule annotationAdd BLAST104
Domaini602 – 668GRAM 2Sequence analysisAdd BLAST67

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi436 – 491Ala-richAdd BLAST56

Sequence similaritiesi

Belongs to the glycosyltransferase 28 family.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

HOGENOMiHOG000034145
InParanoidiQ751Z4
KOiK05841
OMAiWEATHSE
OrthoDBiEOG092C09PF

Family and domain databases

Gene3Di2.30.29.30, 2 hits
InterProiView protein in InterPro
IPR004276 GlycoTrans_28_N
IPR004182 GRAM
IPR011993 PH-like_dom_sf
IPR001849 PH_domain
IPR002213 UDP_glucos_trans
PfamiView protein in Pfam
PF03033 Glyco_transf_28, 1 hit
PF02893 GRAM, 2 hits
PF00169 PH, 1 hit
PF00201 UDPGT, 1 hit
SMARTiView protein in SMART
SM00568 GRAM, 2 hits
SM00233 PH, 1 hit
PROSITEiView protein in PROSITE
PS50003 PH_DOMAIN, 1 hit

Sequencei

Sequence statusi: Complete.

Q751Z4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLKGQKEGEA EPVPEGDKSG AGSSPSGVRK GLRVPLGLVS HSFSSLAKHK
60 70 80 90 100
EAERRLTDEE ESLSSPQDRE DDAASPNIMA KSIAGLLTTA SMYVGIGDIH
110 120 130 140 150
RAEQLATGQP ETDAGADETE DEMDEAGDET GDDADAPATG TDGEEESRPV
160 170 180 190 200
SAQESRRSTL FELSIEPHPE SHTAQASRTK NRRSRMTSKL RSKFNLDDDE
210 220 230 240 250
ELVREYPCWL LRDVLIQGHI YLTSRNLLFF AFLYKSNGSA RLTGNLSICN
260 270 280 290 300
NGLSISGISG KPTRYWTVLK DHTLSLYSSS TDLYFPVLTI DLRYVTKVQH
310 320 330 340 350
CKNNGKDTRQ FHITTESKTY TFYSDNEHSA RSWSSALKKQ VFATQNSDND
360 370 380 390 400
SMSVRIPLSN IIDVEEQAIV EQGLTLRVRV MESSDSFALD DYFFMFFNNA
410 420 430 440 450
GSQLKELIQI QVANLEMLGA ANVDYARHPL PPDTEASLPA VASDAAPQDA
460 470 480 490 500
AIASEAAADA AAADTASHSP STNAEPRARG RSTERAMAAS AYLFGRLTSP
510 520 530 540 550
RRDDAKQLSP SKVKLRFRSV ADTLKLTTPR QPGSDAPQEP EPETTILESR
560 570 580 590 600
PRLNYWSPRP FTTMRSMWNA QPVHYAAKGM SLFADDDELM IGDEAELLAA
610 620 630 640 650
DKRFKAHFSL TDDESLVASY YTYLNRSMPL YGKIYLGKTI MCFRSLLPGS
660 670 680 690 700
KTKMILPLHD VENCYKEQGF RFGYFGLVVV IYGHEELFFE FASQKSRDDA
710 720 730 740 750
EYVILKIIDS LKPVDGVMAD DMSAGAYSLK AAQGRDATTD AKVKLFEQRI
760 770 780 790 800
SSVGYDIPIM VEDNPFYKTT ITPKKFYTFG MLTIGSRGDV QPYIALGKGL
810 820 830 840 850
LQEGHRVVVI SHAEFGDWVR SHGLQFRAIA GDPAELMALM VQHGSMNVGL
860 870 880 890 900
IREAASTFRN WIRDLLETAW EACQGIDVLI ESPSAMAGIH IAEALQIPYF
910 920 930 940 950
RAFTMPWTKT RSYPHAFIVP DQKRGGNYNY FTHVLFENIF WKGINSQVNR
960 970 980 990 1000
WRVEKLGLKK TNLEFMQQGK VPFLYNMSPT VFPPSVDFAE WIKVTGYWFL
1010 1020 1030 1040 1050
NESSNYVPPQ ALLEFMAKAR RLDKKLVYIG FGSIVVKDPV KMTMAVVEAV
1060 1070 1080 1090 1100
VKADVYCILN KGWSARLGGQ SQKSIEVQLP NCVYDAGNVP HDWLFPRVDA
1110 1120 1130 1140 1150
AVHHGGSGTT GATMRAGVPT VIKPFFGDQY FYANRIEDIG AGIALRKLNA
1160 1170 1180 1190 1200
CTLSRALKEV TTNTRIIAKA KKIGQDISKE DGVATAIAFI YSEMAYAKSL
1210 1220
IKAKRQEDKK AAKEAKQIQN EDSWLLL
Length:1,227
Mass (Da):136,399
Last modified:January 9, 2013 - v2
Checksum:i8AD3965B13219B9C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016819 Genomic DNA Translation: AAS54053.2
RefSeqiNP_986229.2, NM_212365.2

Genome annotation databases

EnsemblFungiiAAS54053; AAS54053; AGOS_AFR681W
GeneIDi4622518
KEGGiago:AGOS_AFR681W

Similar proteinsi

Entry informationi

Entry nameiATG26_ASHGO
AccessioniPrimary (citable) accession number: Q751Z4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 16, 2005
Last sequence update: January 9, 2013
Last modified: April 25, 2018
This is version 100 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health