Q750J3 (ALG13_ASHGO) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
UDP-N-acetylglucosamine transferase subunit ALG13
EC=2.4.1.141

Alternative name(s):
Asparagine-linked glycosylation protein 13

Gene names

Name:	ALG13
Ordered Locus Names:	AGL042W

Organism

Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii) [Complete proteome]

Taxonomic identifier

284811 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Eremothecium

Protein attributes

Sequence length	203 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Involved in protein N-glycosylation. Essential for the second step of the dolichol-linked oligosaccharide pathway By similarity.
Catalytic activity	UDP-N-acetyl-D-glucosamine + N-acetyl-D-glucosaminyl-diphosphodolichol = UDP + N,N'-diacetylchitobiosyl-diphosphodolichol.
Subunit structure	Heterodimer with ALG14 to form a functional enzyme By similarity.
Subcellular location	Endoplasmic reticulum By similarity.
Sequence similarities	Belongs to the glycosyltransferase 28 family.

Ontologies

Keywords
Cellular component	Endoplasmic reticulum
Molecular function	Glycosyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	lipid glycosylation Inferred from electronic annotation. Source: InterPro
Cellular component	endoplasmic reticulum Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity Inferred from electronic annotation. Source: EC carbohydrate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 203	203	UDP-N-acetylglucosamine transferase subunit ALG13		PRO_0000215596

Sequences

	Sequence		Length	Mass (Da)
	Q750J3 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: B1BE7EC684D78168	FASTA	203	21,794
	10 20 30 40 50 60 MSTTTKSKME GPKTVVVTCG ATVPFPGLVN AVLDRRVLAE LAQCGFSRVM VQYGRGFAAE 70 80 90 100 110 120 FERQVGAAGA VRAACDAEGL EGCDAHAWRW QGLEIIGFAF HAQMESLIGT SAALVVSHAG 130 140 150 160 170 180 TGSILDALRQ QKPLIVCVNE ALLDNHQEQI ARRFEALGHL WAIRADVDEL AGALARSTRE 190 200 TLAPLPPAYK QGFAELLQDV AHR

References

[1]

"The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces cerevisiae genome." Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S., Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A., Gaffney T.D., Philippsen P. Science 304:304-307(2004) [PubMed: 15001715] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE016820 Genomic DNA. Translation: AAS54448.1.
RefSeq	NP_986624.1. NM_211686.1.
3D structure databases
ProteinModelPortal	Q750J3.
ModBase	Search...
Protein-protein interaction databases
STRING	Q750J3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4622923.
GenomeReviews	Gene locus AGL042W in contig AE016820_GR.
KEGG	ago:AGOS_AGL042W.
NMPDR	fig|33169.1.peg.4269.
Organism-specific databases
AGD	AGL042W.
Phylogenomic databases
eggNOG	fuNOG11732.
HOGENOM	HBG629711.
OMA	LLDNHQV.
OrthoDB	EOG4KM2CB.
PhylomeDB	Q750J3.
Family and domain databases
InterPro	IPR007235. Glyco_trans_28_C. [Graphical view]
KO	K07432.
Pfam	PF04101. Glyco_tran_28_C. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ALG13_ASHGO

Accession

Primary (citable) accession number: Q750J3

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 22, 2005
Last sequence update:	July 5, 2004
Last modified:	December 14, 2011
This is version 53 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program