Reviewed, UniProtKB/Swiss-Prot Q750J3 (ALG13_ASHGO)

Names and originHide

Protein names

Recommended name:
UDP-N-acetylglucosamine transferase subunit ALG13
EC=2.4.1.141

Alternative name(s):
Asparagine-linked glycosylation protein 13

Gene names

Name:	ALG13
Ordered Locus Names:	AGL042W

Organism

Ashbya gossypii (Yeast) (Eremothecium gossypii) [Complete proteome]

Taxonomic identifier

33169 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomyceta › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Eremothecium

Protein attributesHide

Sequence length	203 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)Hide

Function	Involved in protein N-glycosylation. Essential for the second step of the dolichol-linked oligosaccharide pathway By similarity.
Catalytic activity	UDP-N-acetyl-D-glucosamine + N-acetyl-D-glucosaminyl-diphosphodolichol = UDP + N,N'-diacetylchitobiosyl-diphosphodolichol.
Subunit structure	Heterodimer with ALG14 to form a functional enzyme By similarity.
Subcellular location	Endoplasmic reticulum By similarity.
Sequence similarities	Belongs to the glycosyltransferase 28 family.

OntologiesHide

Keywords
Cellular component	Endoplasmic reticulum
Molecular function	Glycosyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro lipid glycosylation Inferred from electronic annotation. Source: InterPro
Cellular component	endoplasmic reticulum Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity Inferred from electronic annotation. Source: EC carbohydrate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)Hide

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 203	203	UDP-N-acetylglucosamine transferase subunit ALG13		PRO_0000215596

SequencesHide

	Sequence		Length	Mass (Da)
	Q750J3-1 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: B1BE7EC684D78168	FASTA	203	21,794
	10 20 30 40 50 60 MSTTTKSKME GPKTVVVTCG ATVPFPGLVN AVLDRRVLAE LAQCGFSRVM VQYGRGFAAE 70 80 90 100 110 120 FERQVGAAGA VRAACDAEGL EGCDAHAWRW QGLEIIGFAF HAQMESLIGT SAALVVSHAG 130 140 150 160 170 180 TGSILDALRQ QKPLIVCVNE ALLDNHQEQI ARRFEALGHL WAIRADVDEL AGALARSTRE 190 200 TLAPLPPAYK QGFAELLQDV AHR

ReferencesHide

[1]

"The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces cerevisiae genome." Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S., Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A., Gaffney T.D., Philippsen P. Science 304:304-307(2004) [PubMed: 15001715] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056.

Cross-referencesHide

Sequence databases
EMBL GenBank DDBJ	AE016820 Genomic DNA. Translation: AAS54448.1.
RefSeq	NP_986624.1.
3D structure databases
SMR	Q750J3. Positions 10-202.
ModBase	Search...
Protein-protein interaction databases
STRING	Q750J3.
Genome annotation databases
GeneID	4622923.
GenomeReviews	Gene locus AGL042W in contig AE016820_GR.
KEGG	ago:AGOS_AGL042W.
NMPDR	fig|33169.1.peg.4269.
Organism-specific databases
AGD	AGL042W.
Phylogenomic databases
eggNOG	fuNOG11732.
HOGENOM	HBG629711.
OMA	PLIVCVN.
OrthoDB	EOG9ZCVN9.
Enzyme and pathway databases
BRENDA	2.4.1.141. 279361.
Family and domain databases
InterPro	IPR007235. Glyco_trans_28_C. [Graphical view]
Pfam	PF04101. Glyco_tran_28_C. 1 hit. [Graphical view]
ProtoNet	Search...

Entry informationHide

Entry name

ALG13_ASHGO

Accession

Primary (citable) accession number: Q750J3

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 22, 2005
Last sequence update:	July 5, 2004
Last modified:	March 23, 2010
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

FPAP (Fungal Proteome Annotation Project)