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Q74ZE6

- Q74ZE6_ASHGO

UniProt

Q74ZE6 - Q74ZE6_ASHGO

Protein
Submitted name:

AGR253Wp

Gene

AGR253W

Organism
Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 79 (01 Oct 2014)
      Sequence version 1 (05 Jul 2004)
      Previous versions | rss
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    Functioni

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei372 – 3721ADPImported

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi456 – 4616ADPImported

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. minus-end-directed microtubule motor activity Source: EnsemblFungi

    GO - Biological processi

    1. karyogamy involved in conjugation with cellular fusion Source: EnsemblFungi
    2. meiotic nuclear division Source: EnsemblFungi
    3. mitotic sister chromatid cohesion Source: EnsemblFungi
    4. nuclear migration involved in conjugation with cellular fusion Source: EnsemblFungi

    Keywords - Molecular functioni

    Motor proteinUniRule annotation

    Keywords - Ligandi

    ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    AGR253WpImported
    Gene namesi
    Ordered Locus Names:AGR253WImported
    ORF Names:AGOS_AGR253WImported
    OrganismiAshbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii)Imported
    Taxonomic identifieri284811 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeEremothecium
    ProteomesiUP000000591: Chromosome VII

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasmic microtubule Source: EnsemblFungi
    2. kinesin complex Source: InterPro

    Keywords - Cellular componenti

    MicrotubuleUniRule annotation

    Interactioni

    Protein-protein interaction databases

    STRINGi33169.AGOS_AGR253W.

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    3T0QX-ray2.35A363-709[»]
    ProteinModelPortaliQ74ZE6.
    SMRiQ74ZE6. Positions 365-703.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.UniRule annotation
    Contains 1 kinesin motor domain.UniRule annotation
    Contains kinesin motor domain.SAAS annotation

    Phylogenomic databases

    HOGENOMiHOG000116164.
    KOiK10405.
    OMAiDVIYALN.
    OrthoDBiEOG7RRFGF.

    Family and domain databases

    Gene3Di3.40.850.10. 1 hit.
    InterProiIPR027640. Kinesin-like_fam.
    IPR019821. Kinesin_motor_CS.
    IPR001752. Kinesin_motor_dom.
    IPR027417. P-loop_NTPase.
    [Graphical view]
    PANTHERiPTHR24115. PTHR24115. 1 hit.
    PfamiPF00225. Kinesin. 1 hit.
    [Graphical view]
    PRINTSiPR00380. KINESINHEAVY.
    SMARTiSM00129. KISc. 1 hit.
    [Graphical view]
    SUPFAMiSSF52540. SSF52540. 1 hit.
    PROSITEiPS00411. KINESIN_MOTOR_DOMAIN1. 1 hit.
    PS50067. KINESIN_MOTOR_DOMAIN2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q74ZE6-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSPPTTPKKQ RDCGYVPSSP SLIPSPRNTS QSPKYQPRAE DPEENRLRVL    50
    NPVDTNQLIN HTKQHQHKEP QSHMTHFYRE NVRQLSYLQD TFMLKKQKLD 100
    LVRDEMVSTR SKVDVLEQKL ERLKEERRSK EQQVLLKENE LRSLCDDSET 150
    KKKFMLQGHD LQLQQVRAKK ESELNQLDSS YRTKWDKLKF MKIQKYEIEK 200
    SSTLEKISNL RSNISDNEES LQKILQDSES KYRELREMWL RNFQDDWKRT 250
    AGENESISKD IDALNKRIND DLEPNVVKEK TAVEELHATL SNLRQQLEAT 300
    KAADVTLMAE TVALANELTK VQQTRKDLGE YISNSQIETK QIKEILVKEE 350
    TMRRKLHNEL QELRGNIRVY CRVRPPLLNE PQDMSHILIE KFNEAKGAQS 400
    LTINRNEGRI LSYNFQFDMI FEPSHTNKEI FEEIRQLVQS SLDGYNVCIF 450
    AYGQTGSGKT YTMLNAGDGM IPMTLSHIFK WTANLKERGW NYEMECEYIE 500
    IYNETILDLL RDFKSHDNID EILDSQKHDI RHDHEKQGTY ITNVTRMKMT 550
    STSQVDTILK KASKMRSTAA TRSNERSSRS HSVFMVHING RNLHTGETSQ 600
    GKLNLVDLAG SERINSSAVT GERLRETQNI NKSLSCLGDV IYALNTPDAG 650
    KRYIPFRNSK LTYLLQYSLV GDSKTLMFVN IPPDPNHISE TLNSLRFASK 700
    VNSTKIAKR 709
    Length:709
    Mass (Da):82,327
    Last modified:July 5, 2004 - v1
    Checksum:i2B51943FA47A0675
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE016820 Genomic DNA. Translation: AAS54743.1.
    RefSeqiNP_986919.1. NM_211981.1.

    Genome annotation databases

    EnsemblFungiiAAS54743; AAS54743; AGOS_AGR253W.
    GeneIDi4623221.
    KEGGiago:AGOS_AGR253W.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE016820 Genomic DNA. Translation: AAS54743.1 .
    RefSeqi NP_986919.1. NM_211981.1.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    3T0Q X-ray 2.35 A 363-709 [» ]
    ProteinModelPortali Q74ZE6.
    SMRi Q74ZE6. Positions 365-703.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 33169.AGOS_AGR253W.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii AAS54743 ; AAS54743 ; AGOS_AGR253W .
    GeneIDi 4623221.
    KEGGi ago:AGOS_AGR253W.

    Phylogenomic databases

    HOGENOMi HOG000116164.
    KOi K10405.
    OMAi DVIYALN.
    OrthoDBi EOG7RRFGF.

    Family and domain databases

    Gene3Di 3.40.850.10. 1 hit.
    InterProi IPR027640. Kinesin-like_fam.
    IPR019821. Kinesin_motor_CS.
    IPR001752. Kinesin_motor_dom.
    IPR027417. P-loop_NTPase.
    [Graphical view ]
    PANTHERi PTHR24115. PTHR24115. 1 hit.
    Pfami PF00225. Kinesin. 1 hit.
    [Graphical view ]
    PRINTSi PR00380. KINESINHEAVY.
    SMARTi SM00129. KISc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52540. SSF52540. 1 hit.
    PROSITEi PS00411. KINESIN_MOTOR_DOMAIN1. 1 hit.
    PS50067. KINESIN_MOTOR_DOMAIN2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces cerevisiae genome."
      Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S., Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A., Gaffney T.D., Philippsen P.
      Science 304:304-307(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056Imported.
    2. "Crystal structure of the Kar3-like kinesin motor domain from the filamentous fungus Ashbya gossypii."
      Duan D., Hnatchuk D.J., Brenner J., Davis D., Allingham J.S.
      Proteins 80:1016-1027(2012) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (2.35 ANGSTROMS) OF 363-709 IN COMPLEX WITH ADP.
    3. "Genomes of Ashbya fungi isolated from insects reveal four mating-type loci, numerous translocations, lack of transposons, and distinct gene duplications."
      Dietrich F.S., Voegeli S., Kuo S., Philippsen P.
      G3 (Bethesda) 3:1225-1239(2013) [PubMed] [Europe PMC] [Abstract]
      Cited for: GENOME REANNOTATION.
      Strain: ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056Imported.

    Entry informationi

    Entry nameiQ74ZE6_ASHGO
    AccessioniPrimary (citable) accession number: Q74ZE6
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 5, 2004
    Last sequence update: July 5, 2004
    Last modified: October 1, 2014
    This is version 79 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    3D-structureImported, Complete proteome, Reference proteomeImported

    External Data

    Dasty 3