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Q74ZE6

- Q74ZE6_ASHGO

UniProt

Q74ZE6 - Q74ZE6_ASHGO

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Protein
Submitted name:

AGR253Wp

Gene

AGR253W

Organism
Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei372 – 3721ADPImported

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi456 – 4616ADPImported

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. minus-end-directed microtubule motor activity Source: EnsemblFungi

GO - Biological processi

  1. karyogamy involved in conjugation with cellular fusion Source: EnsemblFungi
  2. meiotic nuclear division Source: EnsemblFungi
  3. mitotic sister chromatid cohesion Source: EnsemblFungi
  4. nuclear migration involved in conjugation with cellular fusion Source: EnsemblFungi
Complete GO annotation...

Keywords - Molecular functioni

Motor proteinUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
AGR253WpImported
Gene namesi
Ordered Locus Names:AGR253WImported
ORF Names:AGOS_AGR253WImported
OrganismiAshbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii)Imported
Taxonomic identifieri284811 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeEremothecium
ProteomesiUP000000591: Chromosome VII

Subcellular locationi

GO - Cellular componenti

  1. cytoplasmic microtubule Source: EnsemblFungi
  2. kinesin complex Source: InterPro
Complete GO annotation...

Keywords - Cellular componenti

MicrotubuleUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi33169.AGOS_AGR253W.

Structurei

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3T0QX-ray2.35A363-709[»]
ProteinModelPortaliQ74ZE6.
SMRiQ74ZE6. Positions 365-703.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.UniRule annotation
Contains 1 kinesin motor domain.UniRule annotation
Contains kinesin motor domain.SAAS annotation

Phylogenomic databases

HOGENOMiHOG000116164.
InParanoidiQ74ZE6.
KOiK10405.
OMAiDVIYALN.
OrthoDBiEOG7RRFGF.

Family and domain databases

Gene3Di3.40.850.10. 1 hit.
InterProiIPR027640. Kinesin-like_fam.
IPR019821. Kinesin_motor_CS.
IPR001752. Kinesin_motor_dom.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR24115. PTHR24115. 1 hit.
PfamiPF00225. Kinesin. 1 hit.
[Graphical view]
PRINTSiPR00380. KINESINHEAVY.
SMARTiSM00129. KISc. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00411. KINESIN_MOTOR_DOMAIN1. 1 hit.
PS50067. KINESIN_MOTOR_DOMAIN2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q74ZE6-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSPPTTPKKQ RDCGYVPSSP SLIPSPRNTS QSPKYQPRAE DPEENRLRVL
60 70 80 90 100
NPVDTNQLIN HTKQHQHKEP QSHMTHFYRE NVRQLSYLQD TFMLKKQKLD
110 120 130 140 150
LVRDEMVSTR SKVDVLEQKL ERLKEERRSK EQQVLLKENE LRSLCDDSET
160 170 180 190 200
KKKFMLQGHD LQLQQVRAKK ESELNQLDSS YRTKWDKLKF MKIQKYEIEK
210 220 230 240 250
SSTLEKISNL RSNISDNEES LQKILQDSES KYRELREMWL RNFQDDWKRT
260 270 280 290 300
AGENESISKD IDALNKRIND DLEPNVVKEK TAVEELHATL SNLRQQLEAT
310 320 330 340 350
KAADVTLMAE TVALANELTK VQQTRKDLGE YISNSQIETK QIKEILVKEE
360 370 380 390 400
TMRRKLHNEL QELRGNIRVY CRVRPPLLNE PQDMSHILIE KFNEAKGAQS
410 420 430 440 450
LTINRNEGRI LSYNFQFDMI FEPSHTNKEI FEEIRQLVQS SLDGYNVCIF
460 470 480 490 500
AYGQTGSGKT YTMLNAGDGM IPMTLSHIFK WTANLKERGW NYEMECEYIE
510 520 530 540 550
IYNETILDLL RDFKSHDNID EILDSQKHDI RHDHEKQGTY ITNVTRMKMT
560 570 580 590 600
STSQVDTILK KASKMRSTAA TRSNERSSRS HSVFMVHING RNLHTGETSQ
610 620 630 640 650
GKLNLVDLAG SERINSSAVT GERLRETQNI NKSLSCLGDV IYALNTPDAG
660 670 680 690 700
KRYIPFRNSK LTYLLQYSLV GDSKTLMFVN IPPDPNHISE TLNSLRFASK

VNSTKIAKR
Length:709
Mass (Da):82,327
Last modified:July 5, 2004 - v1
Checksum:i2B51943FA47A0675
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE016820 Genomic DNA. Translation: AAS54743.1.
RefSeqiNP_986919.1. NM_211981.1.

Genome annotation databases

EnsemblFungiiAAS54743; AAS54743; AGOS_AGR253W.
GeneIDi4623221.
KEGGiago:AGOS_AGR253W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE016820 Genomic DNA. Translation: AAS54743.1 .
RefSeqi NP_986919.1. NM_211981.1.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
3T0Q X-ray 2.35 A 363-709 [» ]
ProteinModelPortali Q74ZE6.
SMRi Q74ZE6. Positions 365-703.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 33169.AGOS_AGR253W.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii AAS54743 ; AAS54743 ; AGOS_AGR253W .
GeneIDi 4623221.
KEGGi ago:AGOS_AGR253W.

Phylogenomic databases

HOGENOMi HOG000116164.
InParanoidi Q74ZE6.
KOi K10405.
OMAi DVIYALN.
OrthoDBi EOG7RRFGF.

Family and domain databases

Gene3Di 3.40.850.10. 1 hit.
InterProi IPR027640. Kinesin-like_fam.
IPR019821. Kinesin_motor_CS.
IPR001752. Kinesin_motor_dom.
IPR027417. P-loop_NTPase.
[Graphical view ]
PANTHERi PTHR24115. PTHR24115. 1 hit.
Pfami PF00225. Kinesin. 1 hit.
[Graphical view ]
PRINTSi PR00380. KINESINHEAVY.
SMARTi SM00129. KISc. 1 hit.
[Graphical view ]
SUPFAMi SSF52540. SSF52540. 1 hit.
PROSITEi PS00411. KINESIN_MOTOR_DOMAIN1. 1 hit.
PS50067. KINESIN_MOTOR_DOMAIN2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces cerevisiae genome."
    Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S., Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A., Gaffney T.D., Philippsen P.
    Science 304:304-307(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056Imported.
  2. "Crystal structure of the Kar3-like kinesin motor domain from the filamentous fungus Ashbya gossypii."
    Duan D., Hnatchuk D.J., Brenner J., Davis D., Allingham J.S.
    Proteins 80:1016-1027(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.35 ANGSTROMS) OF 363-709 IN COMPLEX WITH ADP.
  3. "Genomes of Ashbya fungi isolated from insects reveal four mating-type loci, numerous translocations, lack of transposons, and distinct gene duplications."
    Dietrich F.S., Voegeli S., Kuo S., Philippsen P.
    G3 (Bethesda) 3:1225-1239(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENOME REANNOTATION.
    Strain: ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056Imported.

Entry informationi

Entry nameiQ74ZE6_ASHGO
AccessioniPrimary (citable) accession number: Q74ZE6
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: October 29, 2014
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureImported, Complete proteome, Reference proteomeImported

External Data

Dasty 3