Reviewed,
UniProtKB/Swiss-Prot Q74Z75 (BUD32_ASHGO)
Last modified
June 16, 2009.
Version 49.
History...
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50% identity |
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: Serine/threonine-protein kinase BUD32 EC=2.7.11.1 | ||||
| Gene names |
| ||||
| Organism | Ashbya gossypii (Yeast) (Eremothecium gossypii) [Complete proteome] | ||||
| Taxonomic identifier | 33169 [NCBI] | ||||
| Taxonomic lineage | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Eremothecium |
Protein attributes
| Sequence length | 260 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Function | Component of the EKC/KEOPS complex which promotes both telomere uncapping and telomere elongation By similarity. The complex is required for efficient recruitment of transcriptional coactivators. Important for bud site selection By similarity. |
| Catalytic activity | ATP + a protein = ADP + a phosphoprotein. |
| Subunit structure | Component of the EKC/KEOPS complex By similarity. |
| Subcellular location | Cytoplasm By similarity. Nucleus By similarity. Telomere By similarity. |
| Sequence similarities | Belongs to the protein kinase superfamily. Tyr protein kinase family. BUD32 subfamily. Contains 1 protein kinase domain. |
Ontologies
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 260 | 260 | Serine/threonine-protein kinase BUD32 | PRO_0000278904 | |||||
Regions | |||||||||
| Domain | 16 – 260 | 245 | Protein kinase | ||||||
| Nucleotide binding | 22 – 30 | 9 | ATP By similarity | ||||||
Sites | |||||||||
| Active site | 160 | 1 | Proton acceptor By similarity | ||||||
| Binding site | 51 | 1 | ATP By similarity | ||||||
Sequences
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References
| [1] | "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces cerevisiae genome." Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S., Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A., Gaffney T.D., Philippsen P. Science 304:304-307(2004) [PubMed: 15001715] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 10895 / NRRL Y-1056 / CBS 109.51. |
Cross-references
Sequence databases | |
|---|---|
| AE016820 Genomic DNA. Translation: AAS54821.1. | |
| RefSeq | NP_986997.1. |
3D structure databases | |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 4623300. |
| KEGG | ago:AGOS_AGR331C. |
| NMPDR | fig|33169.1.peg.4642. |
Organism-specific databases | |
| AGD | AGR331C. |
Phylogenomic databases | |
| HOGENOM | Q74Z75. |
| OMA | Q74Z75. VVYFVDY. |
Enzyme and pathway databases | |
| BRENDA | 2.7.11.1. 279361. |
Family and domain databases | |
| InterPro | IPR000719. Prot_kinase_core. IPR017441. Protein_kinase_ATP_BS. IPR008266. Tyr_pkinase_AS. [Graphical view] |
| ProDom | PD000001. Prot_kinase. 1 hit. [Graphical view] [Entries sharing at least one domain] |
| PROSITE | PS00107. PROTEIN_KINASE_ATP. False negative. PS50011. PROTEIN_KINASE_DOM. 1 hit. PS00109. PROTEIN_KINASE_TYR. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | BUD32_ASHGO | ||||||||
| Accession | Primary (citable) accession number: Q74Z75 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | FPAP (Fungal Proteome Annotation Project) | ||||||||

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