Q74Z75 (BUD32_ASHGO) Reviewed, UniProtKB/Swiss-Prot
Last modified
December 14, 2011.
Version 73.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Serine/threonine-protein kinase BUD32 EC=2.7.11.1 | ||||
| Gene names |
| ||||
| Organism | Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii) [Complete proteome] | ||||
| Taxonomic identifier | 284811 [NCBI] | ||||
| Taxonomic lineage | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Eremothecium |
Protein attributes
| Sequence length | 260 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Function | Component of the EKC/KEOPS complex which promotes both telomere uncapping and telomere elongation By similarity. The complex is required for efficient recruitment of transcriptional coactivators. Important for bud site selection By similarity. |
| Catalytic activity | ATP + a protein = ADP + a phosphoprotein. |
| Subunit structure | Component of the EKC/KEOPS complex By similarity. |
| Subcellular location | Cytoplasm By similarity. Nucleus By similarity. Chromosome › telomere By similarity. |
| Sequence similarities | Belongs to the protein kinase superfamily. Tyr protein kinase family. BUD32 subfamily. Contains 1 protein kinase domain. |
Ontologies
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 260 | 260 | Serine/threonine-protein kinase BUD32 | PRO_0000278904 | |||||
Regions | |||||||||
| Domain | 16 – 260 | 245 | Protein kinase | ||||||
| Nucleotide binding | 22 – 30 | 9 | ATP By similarity | ||||||
Sites | |||||||||
| Active site | 160 | 1 | Proton acceptor By similarity | ||||||
| Binding site | 51 | 1 | ATP By similarity | ||||||
Sequences
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References
| [1] | "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces cerevisiae genome." Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S., Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A., Gaffney T.D., Philippsen P. Science 304:304-307(2004) [PubMed: 15001715] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | AE016820 Genomic DNA. Translation: AAS54821.1. |
| RefSeq | NP_986997.1. NM_212059.1. |
3D structure databases | |
| ProteinModelPortal | Q74Z75. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | Q74Z75. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| GeneID | 4623300. |
| GenomeReviews | Gene locus AGR331C in contig AE016820_GR. |
| KEGG | ago:AGOS_AGR331C. |
| NMPDR | fig|33169.1.peg.4642. |
Organism-specific databases | |
| AGD | AGR331C. |
Phylogenomic databases | |
| eggNOG | fuNOG08130. |
| HOGENOM | HBG574115. |
| OMA | IGMERIE. |
| OrthoDB | EOG4R7ZKZ. |
| PhylomeDB | Q74Z75. |
Family and domain databases | |
| InterPro | IPR022495. Kinase-assoc_endopept-1. IPR011009. Kinase-like_dom. IPR010440. LipoPS_kinase. IPR000719. Prot_kinase_cat_dom. IPR008266. Tyr_kinase_AS. [Graphical view] |
| KO | K08851. |
| Pfam | PF06293. Kdo. 1 hit. [Graphical view] |
| SUPFAM | SSF56112. Kinase_like. 1 hit. |
| TIGRFAMs | TIGR03724. Arch_bud32. 1 hit. |
| PROSITE | PS00107. PROTEIN_KINASE_ATP. False negative. PS50011. PROTEIN_KINASE_DOM. 1 hit. PS00109. PROTEIN_KINASE_TYR. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | BUD32_ASHGO | ||||||||
| Accession | Primary (citable) accession number: Q74Z75 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Fungal Protein Annotation Program | ||||||||
Relevant documents
| SIMILARITY comments Index of protein domains and families |

Clusters with