Q74MA7 (DCD_NANEQ) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable deoxycytidine triphosphate deaminase
Short name=dCTP deaminase
EC=3.5.4.13

Gene names

Name:	dcd
Ordered Locus Names:	NEQ316

Organism

Nanoarchaeum equitans (strain Kin4-M)

Taxonomic identifier

228908 [NCBI]

Taxonomic lineage

Archaea › Nanoarchaeota › Nanoarchaeum

Protein attributes

Sequence length	198 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	dCTP + H2O = dUTP + NH3. HAMAP MF_00146
Pathway	Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2. HAMAP MF_00146
Sequence similarities	Belongs to the dCTP deaminase family.

Ontologies

Keywords
Biological process	Nucleotide metabolism
Molecular function	Hydrolase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	dUTP biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	dCTP deaminase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 198	198	Probable deoxycytidine triphosphate deaminase HAMAP MF_00146		PRO_0000156033

Sequences

	Sequence		Length	Mass (Da)
	Q74MA7 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: 16516FB1DC6E0E7B	FASTA	198	23,245
	10 20 30 40 50 60 MLLNDREIKE LIDKKEIIIE PFSYEQIQPA SIDLRLGNRF RIFRKGEIEV IDPKDFKDEL 70 80 90 100 110 120 IKIEQDENKI IEKYKYTDVI ITENPFIIYP GDFVLASIYE YIKLPRYIAA QLHGKSSIAR 130 140 150 160 170 180 LGLIIHTSAG WIDPGYEGHL TLEIFNTNNV PIKLYPKMKI AQLQLFRINP VERDYKEKGG 190 KYYKEKGATS SEIWKDFI

References

[1]

"The genome of Nanoarchaeum equitans: insights into early archaeal evolution and derived parasitism." Waters E., Hohn M.J., Ahel I., Graham D.E., Adams M.D., Barnstead M., Beeson K.Y., Bibbs L., Bolanos R., Keller M., Kretz K., Lin X., Mathur E., Ni J., Podar M., Richardson T., Sutton G.G., Simon M. , Soell D., Stetter K.O., Short J.M., Noorderwier M. Proc. Natl. Acad. Sci. U.S.A. 100:12984-12988(2003) [PubMed: 14566062] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Kin4-M.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE017199 Genomic DNA. Translation: AAR39163.1.
RefSeq	NP_963602.1. NC_005213.1.
3D structure databases
ProteinModelPortal	Q74MA7.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	2654183.
GenomeReviews	Gene locus NEQ316 in contig AE017199_GR.
KEGG	neq:NEQ316.
Phylogenomic databases
HOGENOM	HBG553199.
OMA	MEYFRIP.
PhylomeDB	Q74MA7.
Family and domain databases
HAMAP	MF_00146. dCTP_deaminase. [Tree]
InterPro	IPR011962. dCTP_deam. IPR008180. dUTP_pyroPase. [Graphical view]
KO	K01494.
Pfam	PF00692. dUTPase. 1 hit. [Graphical view]
TIGRFAMs	TIGR02274. DCTP_deam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DCD_NANEQ

Accession

Primary (citable) accession number: Q74MA7

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 30, 2005
Last sequence update:	July 5, 2004
Last modified:	December 14, 2011
This is version 46 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program