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Q74M98 (IF2B_NANEQ) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 49. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Translation initiation factor 2 subunit beta
Alternative name(s):
aIF2-beta
eIF-2-beta
Gene names
Name:eif2b
Ordered Locus Names:NEQ323
OrganismNanoarchaeum equitans (strain Kin4-M) [Reference proteome] [HAMAP]
Taxonomic identifier228908 [NCBI]
Taxonomic lineageArchaeaNanoarchaeotaNanoarchaeum

Protein attributes

Sequence length139 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA By similarity. HAMAP-Rule MF_00232

Subunit structure

Heterotrimer composed of an alpha, a beta and a gamma chain By similarity.

Sequence similarities

Belongs to the eIF-2-beta/eIF-5 family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Molecular functionInitiation factor
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Molecular_functiontranslation initiation factor activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 139139Translation initiation factor 2 subunit beta HAMAP-Rule MF_00232
PRO_0000137426

Sequences

Sequence LengthMass (Da)Tools
Q74M98 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: D00467EF62BA5582

FASTA13916,665
        10         20         30         40         50         60 
MEYNYFELLE RAYQKLKDVI KQEQIRWNPP IPHIEYVKNR TIITNFKQIA NYLNRDPKII 

        70         80         90        100        110        120 
AKFFSKELFV QTIIEGNSLI INKRVSYETI KKKLDEFINI FVICPVCKRP DTELIERGRK 

       130 
IYYIKCHACG SESPVNYEL 

« Hide

References

[1]"The genome of Nanoarchaeum equitans: insights into early archaeal evolution and derived parasitism."
Waters E., Hohn M.J., Ahel I., Graham D.E., Adams M.D., Barnstead M., Beeson K.Y., Bibbs L., Bolanos R., Keller M., Kretz K., Lin X., Mathur E., Ni J., Podar M., Richardson T., Sutton G.G., Simon M. expand/collapse author list , Soell D., Stetter K.O., Short J.M., Noorderwier M.
Proc. Natl. Acad. Sci. U.S.A. 100:12984-12988(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Kin4-M.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE017199 Genomic DNA. Translation: AAR39172.1.
RefSeqNP_963611.1. NC_005213.1.

3D structure databases

ProteinModelPortalQ74M98.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING228908.NEQ323.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAR39172; AAR39172; NEQ323.
GeneID2654251.
KEGGneq:NEQ323.

Phylogenomic databases

eggNOGCOG1601.
HOGENOMHOG000107197.
KOK03238.
OMAINIFVIC.
ProtClustDBPRK03988.

Enzyme and pathway databases

BioCycNEQU228908:GJB6-343-MONOMER.

Family and domain databases

Gene3D3.30.30.50. 1 hit.
HAMAPMF_00232. eIF_2_beta.
InterProIPR004458. TIF2_bsu_arc.
IPR002735. Transl_init_fac_IF2/IF5.
IPR016189. Transl_init_fac_IF2/IF5_N.
IPR016190. Transl_init_fac_IF2/IF5_Zn-bd.
[Graphical view]
PfamPF01873. eIF-5_eIF-2B. 1 hit.
[Graphical view]
SUPFAMSSF100966. SSF100966. 1 hit.
SSF75689. SSF75689. 1 hit.
ProtoNetSearch...

Entry information

Entry nameIF2B_NANEQ
AccessionPrimary (citable) accession number: Q74M98
Entry history
Integrated into UniProtKB/Swiss-Prot: June 21, 2005
Last sequence update: July 5, 2004
Last modified: February 19, 2014
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Translation initiation factors

List of translation initiation factor entries