Q74M98 (IF2B_NANEQ) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Translation initiation factor 2 subunit beta

Alternative name(s):
aIF2-beta
eIF-2-beta

Gene names

Name:	eif2b
Ordered Locus Names:	NEQ323

Organism

Nanoarchaeum equitans (strain Kin4-M) [Reference proteome] [HAMAP]

Taxonomic identifier

228908 [NCBI]

Taxonomic lineage

cellular organisms › Archaea › Nanoarchaeota › Nanoarchaeum › Nanoarchaeum equitans

Protein attributes

Sequence length	139 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA By similarity. HAMAP-Rule MF_00232
Subunit structure	Heterotrimer composed of an alpha, a beta and a gamma chain By similarity.
Sequence similarities	Belongs to the eIF-2-beta/eIF-5 family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Molecular function	Initiation factor
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular_function	translation initiation factor activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 139	139	Translation initiation factor 2 subunit beta HAMAP-Rule MF_00232		PRO_0000137426

Sequences

	Sequence		Length	Mass (Da)
	Q74M98 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: D00467EF62BA5582	FASTA	139	16,665
	10 20 30 40 50 60 MEYNYFELLE RAYQKLKDVI KQEQIRWNPP IPHIEYVKNR TIITNFKQIA NYLNRDPKII 70 80 90 100 110 120 AKFFSKELFV QTIIEGNSLI INKRVSYETI KKKLDEFINI FVICPVCKRP DTELIERGRK 130 IYYIKCHACG SESPVNYEL

References

[1]

"The genome of Nanoarchaeum equitans: insights into early archaeal evolution and derived parasitism." Waters E., Hohn M.J., Ahel I., Graham D.E., Adams M.D., Barnstead M., Beeson K.Y., Bibbs L., Bolanos R., Keller M., Kretz K., Lin X., Mathur E., Ni J., Podar M., Richardson T., Sutton G.G., Simon M. , Soell D., Stetter K.O., Short J.M., Noorderwier M. Proc. Natl. Acad. Sci. U.S.A. 100:12984-12988(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Kin4-M.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE017199 Genomic DNA. Translation: AAR39172.1.
RefSeq	NP_963611.1. NC_005213.1.
3D structure databases
ProteinModelPortal	Q74M98.
ModBase	Search...
Protein-protein interaction databases
STRING	228908.NEQ323.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAR39172; AAR39172; NEQ323.
GeneID	2654251.
KEGG	neq:NEQ323.
Phylogenomic databases
eggNOG	COG1601.
HOGENOM	HOG000107197.
KO	K03238.
ProtClustDB	PRK03988.
Enzyme and pathway databases
BioCyc	NEQU228908:GJB6-343-MONOMER.
Family and domain databases
Gene3D	3.30.30.50. 1 hit.
HAMAP	MF_00232. eIF-2-beta.
InterPro	IPR004458. TIF2_bsu_arc. IPR002735. Transl_init_fac_IF2/IF5. IPR016189. Transl_init_fac_IF2/IF5_N. IPR016190. Transl_init_fac_IF2/IF5_Zn-bd. [Graphical view]
Pfam	PF01873. eIF-5_eIF-2B. 1 hit. [Graphical view]
SUPFAM	SSF100966. Transl_init_fac_IF2/IF5_N. 1 hit. SSF75689. Transl_init_fac_IF2/IF5_Zn-bd. 1 hit.
ProtoNet	Search...

Entry information

Entry name

IF2B_NANEQ

Accession

Primary (citable) accession number: Q74M98

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 21, 2005
Last sequence update:	July 5, 2004
Last modified:	May 1, 2013
This is version 46 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program