Q74LQ9 (NTD_LACJO) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Nucleoside deoxyribosyltransferase
Short name=N-deoxyribosyltransferase
EC=2.4.2.6

Gene names

Name:	ntd
Ordered Locus Names:	LJ_0124

Organism

Lactobacillus johnsonii (strain CNCM I-12250 / La1 / NCC 533) [Complete proteome] [HAMAP]

Taxonomic identifier

257314 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Lactobacillales › Lactobacillaceae › Lactobacillus › Lactobacillus johnsonii

Protein attributes

Sequence length	149 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the cleavage of the glycosidic bond of 2'-deoxyribonucleosides and the transfer of the deoxyribosyl moiety to an acceptor purine or pyrimidine base By similarity.
Catalytic activity	2-deoxy-D-ribosyl-base1 + base2 = 2-deoxy-D-ribosyl-base2 + base1.
Pathway	Nucleotide metabolism; nucleotide salvage pathway.
Sequence similarities	Belongs to the nucleoside deoxyribosyltransferase family.

Ontologies

Keywords
Biological process	Nucleotide metabolism
Molecular function	Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	deoxyribonucleoside monophosphate catabolic process Inferred from electronic annotation. Source: InterPro nucleotide salvage Inferred from electronic annotation. Source: UniProtKB-UniPathway
Molecular_function	deoxyribonucleoside 5'-monophosphate N-glycosidase activity Inferred from electronic annotation. Source: InterPro nucleoside deoxyribosyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 149	149	Nucleoside deoxyribosyltransferase		PRO_0000220066
Sites
	Active site	90	1	Nucleophile By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q74LQ9 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: 6CE8A86B0553152A	FASTA	149	16,941
	10 20 30 40 50 60 MAGWFTETQN KAYKDAMSAL NANPTIDLEN SYVPLQNQYK DIRVDEHPEY LHDKEWAQAT 70 80 90 100 110 120 YNGDLVGIKT SDVMLGVYVP KEEDVGLGME LGYAMSQGKY VLLVIPDELY GESINLMSWG 130 140 VADNVIKMSE LATFDFNRPR YNFYDGAVY

References

[1]

"The genome sequence of the probiotic intestinal bacterium Lactobacillus johnsonii NCC 533." Pridmore R.D., Berger B., Desiere F., Vilanova D., Barretto C., Pittet A.-C., Zwahlen M.-C., Rouvet M., Altermann E., Barrangou R., Mollet B., Mercenier A., Klaenhammer T., Arigoni F., Schell M.A. Proc. Natl. Acad. Sci. U.S.A. 101:2512-2517(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CNCM I-1225 / La1 / NCC 533.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE017198 Genomic DNA. Translation: AAS08106.1.
RefSeq	NP_964140.1. NC_005362.1.
3D structure databases
ProteinModelPortal	Q74LQ9.
SMR	Q74LQ9. Positions 2-149.
ModBase	Search...
Protein-protein interaction databases
STRING	257314.LJ0124.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAS08106; AAS08106; LJ_0124.
GeneID	2743002.
KEGG	ljo:LJ0124.
PATRIC	22236872. VBILacJoh1832_0133.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG3613.
KO	K08728.
OMA	FYDGAVY.
ProtClustDB	CLSK924961.
Enzyme and pathway databases
BioCyc	LJOH257314:GJN3-130-MONOMER.
UniPathway	UPA00312.
Family and domain databases
InterPro	IPR007710. Nucleoside_deoxyribTrfase. [Graphical view]
Pfam	PF05014. Nuc_deoxyrib_tr. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

NTD_LACJO

Accession

Primary (citable) accession number: Q74LQ9

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 13, 2004
Last sequence update:	July 5, 2004
Last modified:	May 1, 2013
This is version 55 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program