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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Lactobacillus johnsonii (strain CNCM I-12250 / La1 / NCC 533)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciLJOH257314:G1G0M-545-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:LJ_0686
OrganismiLactobacillus johnsonii (strain CNCM I-12250 / La1 / NCC 533)
Taxonomic identifieri257314 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus
Proteomesi
  • UP000000581 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002420351 – 558Arginine--tRNA ligaseAdd BLAST558

Proteomic databases

PRIDEiQ74KR5

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi257314.LJ0686

Structurei

3D structure databases

ProteinModelPortaliQ74KR5
SMRiQ74KR5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi119 – 129"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C75 Bacteria
COG0018 LUCA
KOiK01887
OMAiNKPLHLG

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.701 hit
3.40.50.6201 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit

Sequencei

Sequence statusi: Complete.

Q74KR5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDFKQKVVDL VSEQVDLPKE KISMLIERPK NPKMGDYAFP AFALAKIEHK
60 70 80 90 100
NPALIAKDIA EKISDDNFTS IQAVGPYVNF AIDHAKLVNA TLNDVLTEKE
110 120 130 140 150
HFGDQKLGEG NVPIDMSSPN IAKPMSMGHL RSTVIGNSIA KTLEKVGYTP
160 170 180 190 200
IKINYLGDYG TQFGKLITAY RLWGNEGDVK KDPITNLFHY YVKFHEEAEK
210 220 230 240 250
DPKLEDEGRA AFKKLENGDE EEIKLWKWFR EVSLQEFNRI YKELGVTFDS
260 270 280 290 300
YNGEAFFNDK MQPVVDELRE KGLLEESRGA QVVNLGEDEN PALILKSDGS
310 320 330 340 350
SLYMTRDLAA ALYRKKEYDF VMSLYVAGGE QTGHFKQLKQ VLKKMGYDWS
360 370 380 390 400
DNIHHIPFGL ITQGGKKLST RKGNVVFLDQ VLKDAVSLAE QQIEEKNPNL
410 420 430 440 450
SNKKQVAHDV GVGAVVFHDL KNDRMDNFDF DLEEVVRFEG DTGPYVQYTN
460 470 480 490 500
ARAQSILRKA NKEISMDNLS LNDDWSFAVA KALADFPAIV EKASEKFEPS
510 520 530 540 550
IIAKYALDLS KKFNKYYANV RILDEDNQLN ARLALVQATS IVLTEALRLL

GVNAPKEM
Length:558
Mass (Da):63,028
Last modified:July 5, 2004 - v1
Checksum:iE780DC71AA356BE4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017198 Genomic DNA Translation: AAS08504.1
RefSeqiWP_011161634.1, NC_005362.1

Genome annotation databases

EnsemblBacteriaiAAS08504; AAS08504; LJ_0686
KEGGiljo:LJ_0686
PATRICifig|257314.6.peg.539

Similar proteinsi

Entry informationi

Entry nameiSYR_LACJO
AccessioniPrimary (citable) accession number: Q74KR5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: July 5, 2004
Last modified: February 28, 2018
This is version 91 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome