SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q74K70

- UNG_LACJO

UniProt

Q74K70 - UNG_LACJO

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Uracil-DNA glycosylase
Gene
ung, LJ_0883
Organism
Lactobacillus johnsonii (strain CNCM I-12250 / La1 / NCC 533)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine By similarity.UniRule annotation

Catalytic activityi

Hydrolyzes single-stranded DNA or mismatched double-stranded DNA and polynucleotides, releasing free uracil.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei65 – 651Proton acceptor By similarity

GO - Molecular functioni

  1. uracil DNA N-glycosylase activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. base-excision repair Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Glycosidase, Hydrolase

Keywords - Biological processi

DNA damage, DNA repair

Enzyme and pathway databases

BioCyciLJOH257314:GJN3-745-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uracil-DNA glycosylase (EC:3.2.2.27)
Short name:
UDG
Gene namesi
Name:ung
Ordered Locus Names:LJ_0883
OrganismiLactobacillus johnsonii (strain CNCM I-12250 / La1 / NCC 533)
Taxonomic identifieri257314 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus
ProteomesiUP000000581: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 231231Uracil-DNA glycosylaseUniRule annotation
PRO_0000176106Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi257314.LJ0883.

Structurei

3D structure databases

ProteinModelPortaliQ74K70.
SMRiQ74K70. Positions 1-226.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0692.
KOiK03648.
OMAiWARQGVM.
OrthoDBiEOG6MSS63.

Family and domain databases

Gene3Di3.40.470.10. 1 hit.
HAMAPiMF_00148. UDG.
InterProiIPR018085. Ura-DNA_Glyclase_AS.
IPR002043. Ura_DNA_glycsylse.
IPR005122. Uracil-DNA_glycosylase-like.
[Graphical view]
PANTHERiPTHR11264. PTHR11264. 1 hit.
PfamiPF03167. UDG. 1 hit.
[Graphical view]
SMARTiSM00986. UDG. 1 hit.
[Graphical view]
SUPFAMiSSF52141. SSF52141. 1 hit.
TIGRFAMsiTIGR00628. ung. 1 hit.
PROSITEiPS00130. U_DNA_GLYCOSYLASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q74K70-1 [UniParc]FASTAAdd to Basket

« Hide

MKKLIGNDWD EVLAPAFESE KYQELRDFLK EEYQTKQIFP DMYHIFTAFK    50
LTSFADTKVV ILGQDPYHNP GQATGMSFSV NPGVPLPPSL KNIYKELYDD 100
VGAVPVNHGY LKKWADQGVL LLNAVLTVPY GNANGHRGKG WELITDTAIK 150
ALSDRGKVVF ILWGKFAQNK IPLIDEGKNV IIKSPHPSPF SADRGFFGSR 200
PFSRCNDALI KFGESPIDWQ LPQEVNPADM A 231
Length:231
Mass (Da):25,886
Last modified:July 5, 2004 - v1
Checksum:i4795E80B14218D46
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE017198 Genomic DNA. Translation: AAS08704.1.
RefSeqiNP_964738.1. NC_005362.1.

Genome annotation databases

EnsemblBacteriaiAAS08704; AAS08704; LJ_0883.
GeneIDi2743712.
KEGGiljo:LJ0883.
PATRICi22238120. VBILacJoh1832_0740.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE017198 Genomic DNA. Translation: AAS08704.1 .
RefSeqi NP_964738.1. NC_005362.1.

3D structure databases

ProteinModelPortali Q74K70.
SMRi Q74K70. Positions 1-226.
ModBasei Search...

Protein-protein interaction databases

STRINGi 257314.LJ0883.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAS08704 ; AAS08704 ; LJ_0883 .
GeneIDi 2743712.
KEGGi ljo:LJ0883.
PATRICi 22238120. VBILacJoh1832_0740.

Phylogenomic databases

eggNOGi COG0692.
KOi K03648.
OMAi WARQGVM.
OrthoDBi EOG6MSS63.

Enzyme and pathway databases

BioCyci LJOH257314:GJN3-745-MONOMER.

Family and domain databases

Gene3Di 3.40.470.10. 1 hit.
HAMAPi MF_00148. UDG.
InterProi IPR018085. Ura-DNA_Glyclase_AS.
IPR002043. Ura_DNA_glycsylse.
IPR005122. Uracil-DNA_glycosylase-like.
[Graphical view ]
PANTHERi PTHR11264. PTHR11264. 1 hit.
Pfami PF03167. UDG. 1 hit.
[Graphical view ]
SMARTi SM00986. UDG. 1 hit.
[Graphical view ]
SUPFAMi SSF52141. SSF52141. 1 hit.
TIGRFAMsi TIGR00628. ung. 1 hit.
PROSITEi PS00130. U_DNA_GLYCOSYLASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CNCM I-1225 / La1 / NCC 533.

Entry informationi

Entry nameiUNG_LACJO
AccessioniPrimary (citable) accession number: Q74K70
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 30, 2005
Last sequence update: July 5, 2004
Last modified: May 14, 2014
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi