Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q74K65

- POTA_LACJO

UniProt

Q74K65 - POTA_LACJO

Protein

Spermidine/putrescine import ATP-binding protein PotA

Gene

potA

Organism
Lactobacillus johnsonii (strain CNCM I-12250 / La1 / NCC 533)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 78 (01 Oct 2014)
      Sequence version 1 (05 Jul 2004)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.UniRule annotation

    Catalytic activityi

    ATP + H2O + polyamine(Out) = ADP + phosphate + polyamine(In).UniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi38 – 458ATPUniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-HAMAP
    2. putrescine-importing ATPase activity Source: InterPro
    3. spermidine-importing ATPase activity Source: InterPro

    Keywords - Molecular functioni

    Hydrolase

    Keywords - Biological processi

    Transport

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciLJOH257314:GJN3-750-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Spermidine/putrescine import ATP-binding protein PotAUniRule annotation (EC:3.6.3.31UniRule annotation)
    Gene namesi
    Name:potAUniRule annotation
    Ordered Locus Names:LJ_0888
    OrganismiLactobacillus johnsonii (strain CNCM I-12250 / La1 / NCC 533)
    Taxonomic identifieri257314 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus
    ProteomesiUP000000581: Chromosome

    Subcellular locationi

    Cell membrane UniRule annotation; Peripheral membrane protein UniRule annotation

    GO - Cellular componenti

    1. ATP-binding cassette (ABC) transporter complex Source: UniProtKB-HAMAP

    Keywords - Cellular componenti

    Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 363363Spermidine/putrescine import ATP-binding protein PotAPRO_0000286232Add
    BLAST

    Interactioni

    Subunit structurei

    The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).UniRule annotation

    Protein-protein interaction databases

    STRINGi257314.LJ0888.

    Structurei

    3D structure databases

    ProteinModelPortaliQ74K65.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini5 – 236232ABC transporterUniRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family. [View classification]UniRule annotation
    Contains 1 ABC transporter domain.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG3842.
    KOiK11072.
    OMAiYDEPVND.
    OrthoDBiEOG6T7N3V.

    Family and domain databases

    Gene3Di3.40.50.300. 1 hit.
    InterProiIPR003593. AAA+_ATPase.
    IPR017879. ABC_Sperm/Put_ATP-bd_PotA.
    IPR003439. ABC_transporter-like.
    IPR017871. ABC_transporter_CS.
    IPR008995. Mo/tungstate-bd_C_term_dom.
    IPR027417. P-loop_NTPase.
    IPR005893. Sp_pt_ABC_ATP-bd.
    IPR013611. Transp-assoc_OB_typ2.
    [Graphical view]
    PfamiPF00005. ABC_tran. 1 hit.
    PF08402. TOBE_2. 1 hit.
    [Graphical view]
    SMARTiSM00382. AAA. 1 hit.
    [Graphical view]
    SUPFAMiSSF50331. SSF50331. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR01187. potA. 1 hit.
    PROSITEiPS00211. ABC_TRANSPORTER_1. 1 hit.
    PS50893. ABC_TRANSPORTER_2. 1 hit.
    PS51305. POTA. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q74K65-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSDIIKLKHV RKEYDDGFVA LKDINLTIES GKFYSLLGPS GSGKTTILRI    50
    IAGFSEPTSG QVFFDGQDIT NLDAAKRKIN TVFQNYALFP HMNVFENVAF 100
    GLQIKKKDKQ EIKLAVKEAL HMVQLDGFAN REISELSGGQ QQRVAIARAI 150
    VNQPKVLLLD ESLSALDKRL RKDMQFELRE IQKKLGITFI FVTHDQEEAL 200
    AMSDEIFVLN EGKIQQSGSP VDIYDEPVND FVARFIGDSN ILSGRMIKDY 250
    EVEFGNHRFE CADAGIKPGE KVEVVLRPED LDITDIEHGK LRVVVESQLF 300
    LGDHFEIKAI DSDENEWLIH STNPTKIGKE VGVYFDPEDI HVMRFGESEA 350
    EFDKRLEAYE GEE 363
    Length:363
    Mass (Da):41,103
    Last modified:July 5, 2004 - v1
    Checksum:iB7B6DBDE6EB9B113
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE017198 Genomic DNA. Translation: AAS08709.1.
    RefSeqiNP_964743.1. NC_005362.1.
    WP_004897689.1. NC_005362.1.

    Genome annotation databases

    EnsemblBacteriaiAAS08709; AAS08709; LJ_0888.
    GeneIDi2742720.
    KEGGiljo:LJ0888.
    PATRICi22238130. VBILacJoh1832_0745.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE017198 Genomic DNA. Translation: AAS08709.1 .
    RefSeqi NP_964743.1. NC_005362.1.
    WP_004897689.1. NC_005362.1.

    3D structure databases

    ProteinModelPortali Q74K65.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 257314.LJ0888.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAS08709 ; AAS08709 ; LJ_0888 .
    GeneIDi 2742720.
    KEGGi ljo:LJ0888.
    PATRICi 22238130. VBILacJoh1832_0745.

    Phylogenomic databases

    eggNOGi COG3842.
    KOi K11072.
    OMAi YDEPVND.
    OrthoDBi EOG6T7N3V.

    Enzyme and pathway databases

    BioCyci LJOH257314:GJN3-750-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.300. 1 hit.
    InterProi IPR003593. AAA+_ATPase.
    IPR017879. ABC_Sperm/Put_ATP-bd_PotA.
    IPR003439. ABC_transporter-like.
    IPR017871. ABC_transporter_CS.
    IPR008995. Mo/tungstate-bd_C_term_dom.
    IPR027417. P-loop_NTPase.
    IPR005893. Sp_pt_ABC_ATP-bd.
    IPR013611. Transp-assoc_OB_typ2.
    [Graphical view ]
    Pfami PF00005. ABC_tran. 1 hit.
    PF08402. TOBE_2. 1 hit.
    [Graphical view ]
    SMARTi SM00382. AAA. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50331. SSF50331. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR01187. potA. 1 hit.
    PROSITEi PS00211. ABC_TRANSPORTER_1. 1 hit.
    PS50893. ABC_TRANSPORTER_2. 1 hit.
    PS51305. POTA. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: CNCM I-1225 / La1 / NCC 533.

    Entry informationi

    Entry nameiPOTA_LACJO
    AccessioniPrimary (citable) accession number: Q74K65
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 1, 2007
    Last sequence update: July 5, 2004
    Last modified: October 1, 2014
    This is version 78 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3