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Q74K31

- G6PI_LACJO

UniProt

Q74K31 - G6PI_LACJO

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Protein
Glucose-6-phosphate isomerase
Gene
pgi, LJ_0924
Organism
Lactobacillus johnsonii (strain CNCM I-12250 / La1 / NCC 533)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei288 – 2881Proton donor By similarity
Active sitei309 – 3091 By similarity
Active sitei423 – 4231 By similarity

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciLJOH257314:GJN3-786-MONOMER.
UniPathwayiUPA00109; UER00181.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomerase (EC:5.3.1.9)
Short name:
GPI
Alternative name(s):
Phosphoglucose isomerase
Short name:
PGI
Phosphohexose isomerase
Short name:
PHI
Gene namesi
Name:pgi
Ordered Locus Names:LJ_0924
OrganismiLactobacillus johnsonii (strain CNCM I-12250 / La1 / NCC 533)
Taxonomic identifieri257314 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus
ProteomesiUP000000581: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 447447Glucose-6-phosphate isomeraseUniRule annotation
PRO_0000180658Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi257314.LJ0924.

Structurei

3D structure databases

ProteinModelPortaliQ74K31.
SMRiQ74K31. Positions 5-446.

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.

Phylogenomic databases

eggNOGiCOG0166.
KOiK01810.
OMAiGVESYKR.
OrthoDBiEOG64R61J.

Family and domain databases

HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q74K31-1 [UniParc]FASTAAdd to Basket

« Hide

MSKVVHFDAS KLTPFVHENE LKEMQAMVTA ADQELREGTG AGSDFRGWID    50
LPINYDKDEF DRIKKAAKKI QNDSEVLVGI GIGGSYLGAQ ASIEFLNSSF 100
YGREKEKYPT VVFCGNSLSG SYLYDLLEWL GDKDFSINII SKSGTTTEPS 150
IAFRVLKDKL IKKYGKEEAA KRIYATTDRA KGALKTEADA EGYEEFVVPD 200
DIGGRFSVLS AVGLLPIAVA GGDIDAMMKG AADARAAYTD PDVLKDSPYQ 250
YAAMRNILYR KGYTTELLEN YEPSLRMFGE WWKQLMGESE GKDQKGIYPS 300
SANFTTDLHS LGQYIQEGRR NLMETVIRVE HPTHDVTIPD DKENLDQLNF 350
LSGKTMNYVN DRAYEGVVLA HTDGGVPVMT VDIENQTAHT LGYLIYWFEL 400
AVGISGYLNG INPFNQPGVE SYKRNMFGLL NKPGYEDLHD DLTKRLK 447
Length:447
Mass (Da):49,910
Last modified:July 5, 2004 - v1
Checksum:i80AF7428EC3F69F5
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE017198 Genomic DNA. Translation: AAS08745.1.
RefSeqiNP_964779.1. NC_005362.1.

Genome annotation databases

EnsemblBacteriaiAAS08745; AAS08745; LJ_0924.
GeneIDi2742521.
KEGGiljo:LJ0924.
PATRICi22238202. VBILacJoh1832_0781.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE017198 Genomic DNA. Translation: AAS08745.1 .
RefSeqi NP_964779.1. NC_005362.1.

3D structure databases

ProteinModelPortali Q74K31.
SMRi Q74K31. Positions 5-446.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 257314.LJ0924.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAS08745 ; AAS08745 ; LJ_0924 .
GeneIDi 2742521.
KEGGi ljo:LJ0924.
PATRICi 22238202. VBILacJoh1832_0781.

Phylogenomic databases

eggNOGi COG0166.
KOi K01810.
OMAi GVESYKR.
OrthoDBi EOG64R61J.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00181 .
BioCyci LJOH257314:GJN3-786-MONOMER.

Family and domain databases

HAMAPi MF_00473. G6P_isomerase.
InterProi IPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view ]
PANTHERi PTHR11469. PTHR11469. 1 hit.
Pfami PF00342. PGI. 1 hit.
[Graphical view ]
PRINTSi PR00662. G6PISOMERASE.
PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CNCM I-1225 / La1 / NCC 533.

Entry informationi

Entry nameiG6PI_LACJO
AccessioniPrimary (citable) accession number: Q74K31
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 29, 2005
Last sequence update: July 5, 2004
Last modified: June 11, 2014
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi